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Portrait of a Villain: Laban the Aramean in Rabbinic Literature

Popular Abstract in Swedish Syftet med denna studie är att försöka förklara varför araméen Laban, vilken i Bibeln (Genesis) framstår som en ganska harmlös bifigur, i rabbinsk litteratur i allmänhet betraktas som en av Jakobs och därmed Israels stora fiender. Avhandlingen hävdar att bilden av Laban som en skurk utvecklats som ett resultat av rabbinsk hermeneutik och att de egenskaper som tillskrivsThis study attempts to answer the question of why Laban the Aramean, a rather harmless character as presented in the biblical text, is generally portrayed in rabbinic literature as a major enemy of Jacob and Israel. It is argued that the portrait of Laban as a villain developed as a result of rabbinic hermeneutics, and that the characteristics which are attributed to him in rabbinic literature wer

Structure of the Cyanobacterial Magnesium Chelatase H Subunit Determined by Single Particle Reconstruction and Small-angle X-ray Scattering

The biosynthesis of chlorophyll, an essential cofactor for photosynthesis, requires the ATP-dependent insertion of Mg2+ into protoporphyrin IX catalyzed by the multisubunit enzyme magnesium chelatase. This enzyme complex consists of the I subunit, an ATPase that forms a complex with the D subunit, and an H subunit that binds both the protoporphyrin substrate and the magnesium protoporphyrin produc

Biomarkers of rapid chronic kidney disease progression in type 2 diabetes.

Here we evaluated the performance of a large set of serum biomarkers for the prediction of rapid progression of chronic kidney disease (CKD) in patients with type 2 diabetes. We used a case-control design nested within a prospective cohort of patients with baseline eGFR 30-60 ml/min per 1.73 m(2). Within a 3.5-year period of Go-DARTS study patients, 154 had over a 40% eGFR decline and 153 controls

Altered CSF Orexin and α-Synuclein Levels in Dementia Patients.

Neurodegenerative dementia, most frequently represented by Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), is often accompanied by altered sleeping patterns and excessive daytime sleepiness. Studies showing an association between the neuropeptide orexin and AD/DLB-related processes such as amyloid-β (Aβ)1-42 plaque formation, α-synuclein accumulation, and inflammation indicate that o

Enzyme Hydrolysis of Cellulose Derivatives. Active Site Studies and Polymer Characterisation.

Popular Abstract in Swedish Cellulosa är ett av de vanligast förekommande biologiska ämnena på jorden och en mycket viktig råvara. Cellulosa är en polymer, uppbyggd av glukosmolekyler som är bundna till varandra i kedjor. Kedjorna kan bli mycket långa och består ofta av flera tusen glukosmolekyler. Eftersom cellulosakedjor är lineära kan de packa sig parallellt med varandra och bilda styva fibrer Soluble derivatives of cellulose have become increasingly important in industrial products e.g. in pharmaceutical applications and in technical dispersions. The polymer characteristics of modified celluloses are to a high degree determined by the substituent distribution along the polymeric backbone. The distribution will be more or less heterogeneous both due to the fact that polymers from renewa

Homopolysaccharide metabolism in Lactobacillus reuteri and Pediococcus parvulus

Popular Abstract in Swedish Denna avhandling beskriver den centrala metabolismen och produktionen av exopolysackarider (EPS) hos två olika mjölksyrabakterier: Lactobacillus reuteri och Pediococcus parvulus. Mjölksyrabakterier används inom livsmedelsindustrin som startkulturer i olika mjölkbaserade produkter. Generellt utnyttjas en specifik metabol väg för nerbrytningen av sockerkällan till mjölksyThis thesis deals with the central carbohydrate metabolism and exopolysaccharide (EPS) formation in two different lactic acid bacteria (LAB): Lactobacillus reuteri and Pediococcus parvulus. LAB are traditionally used as starter cultures in the food industry. In general, LAB harbours one glycolytic pathway converting carbohydrates into lactic acid. However, L. reuteri ATCC 55730 was proven to use t

Buoyancy Effects on Developing Laminar Gas Flow and Heat Transfer in a Rectangular Fuel Cell Duct

Using a general 3-D finite-volume code, the development of buoyancy force driven secondary flow and its effects on developing laminar flow and heat transfer have been numerically simulated for a horizontal fuel cell duct with a rectangular cross section. The constant thermal-properties assumption except for linear density variation with temperature in the body force term is applied, and a constant

Altered endothelial/pericyte ratio in Goto-Kakizaki rat retina

The Goto-Kakizaki (GK) rat represents a model of hereditary non-insulin-dependent diabetes mellitus (NIDDM), characterized by nonobesity, mild hyperglycemia from early life, impaired glucose tolerance test results, and a markedly defective insulin response to glucose. The rats develop signs of both nephropathy and neuropathy, but, to our knowledge, retinal changes have not been reported so far in

High prevalence of Hepatozoon spp. (Apicomplexa, hepatozoidae) infection in water pythons (Liasis fuscus) from tropical Australia

Molecular methods were used to identify blood parasites frequently observed in blood smears of water pythons (Liasis fuscus) captured in our study area in the Northern Territory of Australia. A nested polymerase chain reaction (PCR) using primers amplifying the 18s ribosomal RNA (IRNA) nuclear gene resulted in a short PCR product (180 bp) matching this region in the genus Hepatozoon. However, beca

Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation

Uniquely amongst vitamin K-dependent coagulation proteins, protein C interacts via its Gla domain both with a receptor, the endothelial cell protein C receptor (EPCR), and with phospholipids. We have studied naturally occurring and recombinant protein C Gla domain variants for soluble (s)EPCR binding, cell surface activation to activated protein C (APC) by the thrombin-thrombomodulin complex, and

Validation of the Lund-Malmö, Chronic Kidney Disease Epidemiology (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) equations to estimate glomerular filtration rate in a large Swedish clinical population.

Abstract Objective. The aim of this study was to validate externally the Swedish Lund-Malmö revised creatinine-based glomerular filtration rate (GFR) equations (LM Revised) in a Swedish cohort in comparison with the North American Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology (CKD-EPI) equations. Material and methods. The study included 1397 examinations [med

The Role of CSR in Sustainable Swedish Startups - Beyond Sustainability as an Exclusive Selling Poin

Research Problem: Existent literature has predominantly focused on applying the concept of CSR on large corporations, disregarding the role of CSR in startups despite the fact that CSR related aspects especially in relation to sustainability provide a fruitful avenue for new ventures to base their competitive advantage on. Investigation of the link between CSR and startups is needed since emerging

Adaptive Control of Arm Movement based on Cerebellar Model

This study is an attempt to take advantage of a cerebellar model to control a biomimetic arm. Aware that a variety of cerebellar models with different levels of details has been developed, we focused on a high-level model called MOSAIC. This model is thought to be able to describe the cerebellar functionality without getting into the details of the neural circuitry. To understand where this model

An XML Representation of DAE Systems Obtained from Continuous-Time Modelica Models

This contribution outlines an XML format for representation of differential-algebraic equations (DAE) models obtained from continuous time Modelica models and possibly also from other equation-based modeling languages. The purpose is to offer a standardized model exchange format which is based on the DAE formalism and which is neutral with respect to model usage. Many usages of models go beyond wh

Maximizing Positive User Experience at a career-coaching program – A focus on the perspective of Universal Design

Universal Design is a design principle that has been in recent years gaining growing prevalence in the design of physical and social environments and product innovation. Universal Design is referred to as the process of creating products, services, and environments for people with a wide range of (dis)abilities and other characteristics, without special adaptation ‘to the greatest extent possible.

Considering future precipitation in delineation locations for water storage systems - Case study Sri Lanka

Demand for the usable water is accumulating globally in parallel with the population growth and the industrial revolution. Nevertheless, availability and accessibility of the usable water is progressively subsiding due to many environmental and socio-economic reasons. This discrepancy can lead the world to a water crisis unless it takes necessary actions to enhance the sustainable use of existing

Geolocating Alfa Laval's products using supervised machine learning

Geografisk lokalisering av Alfa Lavals produkter med hjälp av maskininlärning. Datakvalitet är en nödvändighet för att ett företag ska kunna bli datadrivna. Detta arbete använder maskinintelligens för att förbättra Alfa Lavals datakvalitet, genom att prediktera den geografiska positionen av deras sålda produkter. Majoriteten av världens företag har data som, på ett eller annat sätt, kan användas fA lot of companies have data that can be used to develop a more successful business. To become more data-driven, it is important to extract valuable information from the raw data. One of the largest challenges for companies, while trying to make this transition, is to ensure a data quality at a high level. In this thesis, we worked with Alfa Laval’s database of previously sold products. The main i

Marknadsundersökningar som bevismedel i marknadsföringsmål

Marknadsundersökningar används som bevismedel, både i marknadsrättsliga och i varumärkesrättsliga tvister. I denna uppsats behandlas marknadsundersökningar inom marknadsföringsrätten i mål som rör vilseledande efterbildningar enligt 14 § MFL. En vilseledande efterbildning innebär att en näringsidkare i sin marknadsföring använder efterbildningar som är vilseledande genom att de lätt kan förväxlas Market surveys are used as evidence both in cases relating to marketing law and trademark law. This essay will discuss market surveys used as evidence within marketing law, and specifically in cases concerning misleading imitations according to 14 § MFL (The Swedish Marketing Act). A misleading imitation means that a trader in its marketing uses imitations that are misleading, as they can easily b