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Expression of prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in ileum and other extraprostatic tissues

Prostate-specific antigen (PSA) is a widely used marker for prostate cancer. In the literature, there are reports of nonprostatic expression of PSA that potentially can affect early diagnosis. However, the results are scattered and inconclusive, which motivated us to conduct a more comprehensive study of the tissue distribution of PSA and the closely related protein human glandular kallikrein 2 (h

Prior information in fluorescence molecular tomography based on multispectral fluorescence emission

Fluorescence molecular tomography (FMT) suffers from inherent ill-posedness due to the vast number of possible solutions to the reconstruction problem. To increase the robustness of such a problem one need prior information. We present here a method for rendering a priori information of the position of a fluorescent inclusion inside turbid media. The method utilizes solely two spectral bands withi

Impact of chronic heart failure on elderly persons' daily life: A validation study.

Background Knowledge about how elderly persons perceive the impact of chronic heart failure (CHF) on daily life is important when planning nursing care. For this purpose, disease specific instruments are needed. However, few instruments have been developed or tested specifically on elderly persons. Aim To validate a Swedish version of the Minnesota Living with Heart Failure Questionnaire (LHFQ)

Assessment of volume of fluid and immersed boundary methods for droplet computations

The volume of fluid (VOF) and immersed boundary (IB) methods are two popular computational techniques for multi-fluid dynamics. To help shed light on the performance of both techniques, we present accuracy assessment, which includes interfacial geometry, detailed and global fluid flow characteristics, and computational robustness. The investigation includes the simulations of a droplet under stati

From Green Image to Green Practice : Normative action and self-regulation

Ever since environmental issues appeared on the agenda of modern industrial society, through the work of whistle blowers such as Rachel Carson, Georg Borgström, Björn Gillberg and Hans Palmstierna, the Swedish state has exerted itself to project a green image. In practice this image has merely functioned as a defence for the legitimacy of industrial development. The state has created environmental

Lack of Reactive Oxygen Species Breaks T Cell Tolerance to Collagen Type II and Allows Development of Arthritis in Mice.

The view on reactive oxygen species (ROS) in inflammation is currently shifting from being considered damaging toward having a more complex role in regulating inflammatory reactions. We recently demonstrated a role of ROS in regulation of animal models for the autoimmune disease rheumatoid arthritis. Low levels of ROS production, due to a mutation in the Ncf1 gene coding for the Ncf1 (alias p47pho

Development of multi-disciplinary team I-ADL assessment in community health care: an interrater reliability study of the measure of instrumental daily activity

This paper describes a development process concerning the active involvement of staff of different professions in developing and implementing methods for assessment of activities of daily living (ADL) in home-based geriatric rehabilitation. Although a variety of established ADL instruments exist, at the time for this study no I-ADL (Instrumental Activities of Daily Living) instrument suitable for

Value Dimensions, Meaning, and Complexity in Human Occupation – A Tentative Structure for Analysis.

In occupational therapy and occupational science, it is important to clarify the perspective from which the analysis of occupation is addressed. The purpose of this paper is to present a tentative structure for describing occupation, allowing for analysis in a lifelong panorama as well as for the immediate experience a person acquires from performing a single occupation. The concept of occupationa

Housing matters in very old age - yet differently due to ADL dependence level differences.

In order to support the development of optimal housing options for older people, we need to increase our understanding of relations between aspects of housing and aspects of health in old and very old age. The objective of this cross-sectional study was to explore whether and how aspects of housing are related to life satisfaction and perceived health among very old, single-living Swedish people.

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Popular Abstract in DanishLivsbaner gennem et felt viser hvorledes eliteidrætsudøvere klarer sig i samfundet efter livet i sporten. Spørgsmålet er om erhvervelse af fysisk sportskapital i sportsfeltet, medieret gennem berømmelse, medvirker til at opnå et arbejde eller en bestemt placering i samfundet. Sportskapital bidrager måske til social mobilitet. Dette er belyst gennem konkrete undersøgelser The thesis deals with a theoretical outline of the theory of reconversions in the light of the social space, with an analysis of top level athletes' mobility and strategies of reconversions in their trajectories through the relative autonomous field of sports. Some disciplines in this field have much autonomy, others less, and are positioned according to a state of distribution of the specific cap

Infection of BALB/c A mice by spiral and coccoid forms of Helicobacter pylori

Helicobacter pylori exists in two different morphological forms, spiral and coccoid. This study demonstrated that both forms can infect BALB/c A mice. The animals were inoculated orally three times at 2-day intervals with 10(8) cfu of both spiral and coccoid forms of strain CCUG 17874 (NCTC 11637), strain 25 and strain 553/93. Infection was followed over a 30-week period by histological scoring of

Enolase of Streptococcus pneumoniae Binds Human Complement Inhibitor C4b-Binding Protein and Contributes to Complement Evasion.

Streptococcus pneumoniae (pneumococcus) is a pathogen that causes severe local and life-threatening invasive diseases, which are associated with high mortality rates. Pneumococci have evolved several strategies to evade the host immune system, including complement to disseminate and to survive in various host niches. Thus, pneumococci bind complement inhibitors such as C4b-binding protein (C4BP) a

Double Helix Relationships in Use and Design of Informing Systems: Lessons to Learn from Phenomenology and Hermeneutics

The theme of this monograph of Informing Science is a dialectic we perceive to exist between meaningful use and reflection upon use. This dialectic between use and reflection on use (or thinking, and thinking about thinking) may be considered in the following way. Each of these elements is subject to change. As reflection triggers change in use, and such change triggers further reflection, a spira

Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix.

Components derived from cartilage have been suggested to maintain the inflammation in joints in arthritis. Small leucine-rich repeat proteins (SLRPs) are structural components of cartilage important in organizing the meshwork of extracellular matrix components. It has recently been shown that the SLRP fibromodulin interacts with complement initiator C1q, leading to complement activation. The compl

Gene-ID Using Simultaneous DNA Barcoding and Enzymatic Labeling

Plasmider är korta cirkulära DNA-molekyler, som kan hittas i de flesta bakterier. Detta projekt handlar om att skapa och testa ett nytt sätt att identifiera plasmider, samt specifika gener på dessa. Principen bygger på att kombinera en tidigare metod kallad “Competitive binding-based optical DNA mapping”, och infärgning av en längre DNA-sekvens med fluoroscerande (självlysande) molekyler, för att Antibiotic resistance is an ever growing problem, and is considered one of the major challenges of modern medicine. In order to avoid further development and spread of multiresistance among bacteria, the use of antibiotics should be more restrictive, and more tailored to individual cases of infection. To facilitate more directed treatments, it is crucial to be able to quickly and reliably identify

Svensk miljöpolitik ut ett ekomarxistiskt perspektiv: En jämförelse mellan Miljöpartiet, Feministiskt initiativ och Vänsterpartiet

Emma Holmberg Svensk miljöpolitik ur ett ekomarxistiskt perspektiv En jämförelse mellan Miljöpartiet, Feministiskt initiativ och Vänsterpartiet Syftet med denna uppsats är att utreda hur Miljöpartiet (MP), Feministiskt initiativ (Fi) och Vänsterpartiet (V), i intervjuer samt genom formuleringar i partiprogram, förhåller sig till miljöproblem relaterade till de tre ekomarxistiska fokusområdena ”This study aims to evaluate whether or not the Swedish Left Party, the Green Party and the Feminist initiative find it possible to operate a sustainable environmental policy within a capitalist system. The methods used for this study have been a literature review of ecomarxist theories as well as a qualitative text analysis of the party programmes of the three parties. The empirical data the study

Imaging stellar surfaces with intensity interferometry

Stjärnorna på himlen syns vara små eftersom de är avlägsna objekt, solar på enorma avstånd. Den närmaste stjärnan är Alfa Centauri på ett avstånd av 4,4 ljusår, cirka 41 miljon miljoner kilometer. Solen är den enda stjärna vars yta vi kan se i detalj medan andra stjärnor är så avlägsna att de inte ens i de största teleskopen syns som mer än små ljusa prickar. De skarpaste bilder som i dag erhållContext. Intensity interferometry was invented and used by R.Hanbury Brown and R.Q.Twiss in the 1960's to measure stellar angular diameters. Its main advantage over conventional interferometry is that it enables very long baselines and is insensitive to poor seeing. However, because it requires very large light collectors, it was never pursued further. The Cherenkov Telescope Array (CTA) is a

A literature review of FASERν - An emulsion detector for collider neutrinos

480 meter bortom Standardmodellen - FASER letar där ingen letat förut Under 2020 har ett nytt experiment börjat ta form vid Large Hadron Collider, LHC, på CERN. Projektet ska försöka fånga upp lätta, extremt svagt växelverkande partiklar som (de flesta av) dagens partikeldetektorer missar. Syftet är att hitta fysik bortom Standardmodellen samt att vidare kartlägga svårfångade neutriner. När partIn 2021, the ForwArd Search ExpeRiment (FASER) will start searching for light and weakly coupled particles 480m from the proton-proton collision point of ATLAS at the Large Hadron Collider (LHC). The FASER main detector will have a sub-detector, FASERν, sensitive to high-energy collider neutrinos of all flavours. This literature review of FASERν focuses on the neutrino program of FASER and apart f