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Introduction

Introduction Printed from: Hommage à Wlodek. Philosophical Papers Dedicated to Wlodek Rabinowicz. Ed. T. Rønnow-Rasmussen, B. Petersson, J. Josefsson & D. Egonsson, 2007. www.fil.lu.se/hommageawlodek 1 Requirements John Broome Corpus Christi College, University of Oxford john.broome@philosophy.ox.ac.uk ABSTRACT: Expressions such as ‘morality requires’, ‘prudence requires’ and ‘rationality requires

https://www.fil.lu.se/hommageawlodek/site/papper/BroomeJohn.pdf - 2026-05-24

Extraction of sugarcane bagasse arabinoxylan, integrated with enzymatic production of xylo-oligosaccharides and separation of cellulose

Sugarcane processing roughly generates 54 million tonnes sugarcane bagasse (SCB)/year, making SCB an important material for upgrading to value-added molecules. In this study, an integrated scheme was developed for separating xylan, lignin and cellulose, followed by production of xylo-oligosaccharides (XOS) from SCB. Xylan extraction conditions were screened in: (1) single extractions in NaOH (0.25

Experience of pain and lifestyle risk factors.

Background Patients with acute and chronic pain have a significantly reduced quality of life, and it is a clinical impression thatunhealthy lifestyle influences the experience of pain. To evaluate this, surgery can be seen as a controlled trauma and acutepain model with standardised guidelines. The aim was to investigate the association between lifestyle risk factors and experience of heavy postop

En flexibel regel för en sprintande värld - En studie av 36 § AvtL i ljuset av social acceleration

Denna uppsats syftar till att belysa hur social acceleration kan förstås påverka lagstiftningsprocessen och lagstiftningsprodukten. Med utgångspunkt i 36 § AvtL, undersöks hur social acceleration speglas i lagstiftningsarbetet. Detta görs särskilt i förhållande till den problembild lagstiftaren beskriver, lagens syfte och slutligen hur detta tar sig uttryck i dess utformning. För att uppnå detta sThis paper aims to shed light on the impact of social acceleration on the legislative process and the legislative product. § 36 of the Swedish Contracts Act (henceforth referred to as the Contracts Act) forms the basis for an examination of how social acceleration is reflected in the legislative process. This is in relation to the problem described by the legislator, the purpose of the law and fin

Motiv med mening? : Att tolka Pompejis ingångsmosaiker

The ancient city of Pompeii presents a wide range of mosaic-floors that drew inspiration from both the Hellenistic tradition and its Roman successor. By the time the city was buried by the eruption of Vesuvius in A.D. 79, a number of atrium-houses were decorated with mosaic-floors, although this floor type never surpassed the more popular version of the cement floors. A certain group of mosaics, f

Cytotoxic lymphocytes in COPD airways : Increased NK cells associated with disease, iNKT and NKT-like cells with current smoking

Background: Cytotoxic lymphocytes are increased in the airways of COPD patients. Whether this increase is driven primarily by the disease or by smoking is not clear, nor whether it correlates with the rate of decline in lung function. Methods: Bronchoscopy with BAL was performed in 52 subjects recruited from the longitudinal OLIN COPD study according to pre-determined criteria; 12 with COPD and a

TRIPS 2.0 : Toward more comprehensive modeling of radiocaesium cycling in forest

Because internal transfers can play a key role in radiocaesium persistence in trees, a reliable representation of radiocaesium recycling between tree organs in forest models is important for long-term simulations after radioactive fallout in Chernobyl and Fukushima. We developed an upgraded 2.0 version of the initial TRIPS (“Transfer of Radionuclides In Perennial vegetation System”) model involvin

In silico analysis and experimental validation shows negative correlation between miR-1183 and cell cycle progression gene 1 expression in colorectal cancer

MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression by binding to the 3' untranslated regions (UTR) of target genes. Aberrant expression of miRNAs can lead to disease, including cancer. Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Among several factors, differential expression of miRNA can have serious consequ

Generation of (synthetic) influent data for performing wastewater treatment modelling studies

The success of many modelling studies strongly depends on the availability of sufficiently long influent time series - the main disturbance of a typical wastewater treatment plant (WWTP) - representing the inherent natural variability at the plant inlet as accurately as possible. This is an important point since most modelling projects suffer from a lack of realistic data representing the infl

Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands.

BACKGROUND. Hypoxia induces increased tumor growth by promoting angiogenic and glycolytic pathways. Tumors expressing hypoxia-inducible factor-la (HIF-1 alpha), an important transcriptional activator of oxygen-regulated genes, are resistant to chemotherapy and radiotherapy. The major challenge in prostate cancer therapy today is to gain a better understanding of the development of hormone-refracto

Bjurkärr – en småländsk bokskog med unika lavar och svampar.

The old beech forest (250–300 yr) at Bjurkärr (core area 30 ha) in the province of Småland, S Sweden, was surveyed for epiphytic lichens of conservation concern in 1993–94. Several rare red-listed lichens were recorded, many with large populations. In 2011 the most endangered lichens were resurveyed due to the incorporation of Bjurkärr in the forthcoming national park of Lake Åsnen. Most species o

Nature and significance of endoleaks and endotension: summary of opinions expressed at an international conference

OBJECTIVE: Endoleaks and endotension are critically important complications of some endovascular aortic aneurysm repairs (EVARs). For the resolution of controversial issues and the determination of areas of uncertainty relating to these complications, a conference of 27 interested leaders was held on November 20, 2000. METHODS: These 27 participants (21 vascular surgeons, five interventional radio

Targeting T cell migration in inflammatory bowel disease.

Crohn's disease and ulcerative colitis are chronic inflammatory disorders of the gastrointestinal tract, and are collectively referred to as inflammatory bowel disease (IBD). IBD is a major cause of lifetime morbidity, has a severe impact on quality of life of patients (equivalent to that of rheumatoid arthritis, asthma, migraine, or diabetes) and constitutes a substantial economic burden to the h

Pollinator attraction to volatiles from virgin and pollinated host flowers in a yucca/moth obligate mutualism

The classic obligate pollination–seed consumption mutualism between yuccas and yucca moths has been thought to be mediated by chemical cues, but empirical data on pollinator attraction to host floral volatiles in this association have been lacking. Here we show that the scent from virgin flowers of the host Yucca glauca is sufficient to attract its obligate pollinator Tegeticula yuccasella in Y-tu

Hyaluronan reflects the pre-fibrotic inflammation in irradiated rat lung: concomitant analysis of parenchymal tissues and bronchoalveolar lavage

The pathogenesis of pulmonary fibrosis is a complicated chain of interactions between cells and molecules. During recent years bronchoalveolar lavage (BAL) in patients with various interstitial lung disorders has increased our knowledge of the fibrosis process and focused on new interesting interactions. Here we present an animal model which makes it possible to apply both morphological and immuno

ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation.

ApoA-I, the main protein component of high-density lipoprotein (HDL), is suggested to be involved in metabolic homeostasis. We examined the effects of Milano, a naturally occurring ApoA-I variant, about which little mechanistic information is available. Remarkably, high fat-fed mice treated with Milano displayed a rapid weight loss greater than ApoA-I WT treated mice, and a significantly reduced a

High resolution scanning gate microscopy measurements on InAs/GaSb nanowire Esaki diode devices

Gated transport measurements are the backbone of electrical characterization of nanoscale electronic devices. Scanning gate microscopy (SGM) is one such gating technique that adds crucial spatial information, accessing the localized properties of semiconductor devices. Nanowires represent a central device concept due to the potential to combine very different materials. However, SGM on semiconduct

A generalized birthday approach for efficiently finding linear relations in l-sequences

Feedback with carry shift registers (FCSRs) have previously been available in two configurations, the Fibonacci and Galois architectures. Recently, a generalized and unifying FCSR structure and theory was presented. The new ring FCSR model repairs some weaknesses of the older architectures. Most notably, the carry cell bias property that was exploited for an attack on the eSTREAM final portfolio c

Benchmark simulation model no 2: general protocol and exploratory case studies

Over a decade ago, the concept of objectively evaluating the performance of control strategies by simulating them using a standard model implementation was introduced for activated sludge wastewater treatment plants. The resulting Benchmark Simulation Model No 1 (BSM1) has been the basis for a significant new development that is reported on here: Rather than only evaluating control strategies at t

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional candidate tumour suppressor genes. In a previous study, functional evidence for a neuroblastoma suppressor gene on chromosome 11 was obtained through m