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Montelukast in the treatment of asthma and beyond

Asthma is a chronic inflammatory disease affecting over 300 million people worldwide. The common association with allergic rhinitis and the presence of proinflammatory cells and mediators in the circulation of patients qualify asthma as a systemic disease. This characteristic and the fact that the gold-standard therapy for persistent asthma, inhaled corticosteroids, cannot suppress all components

Vilnius full of space

Today, one of the main economic engines is construction field. A few periods of history showed that in Lithuania, the main goal for the companies were to build fast, cheap dwellings on the empty lots. The capital of Lithuania, Vilnius city is not an exception. City is built ineffectively. Functions, neighbourhoods are far apart from each other and the transportation ineffectiveness leads to the lo

Shit Matters! Assessing sociocultural barriers and opportunities for upscaling adoption of human faeces derived fertilizers in central Uganda

Nutrient recovered faecal sludge is a novel alternative fertilizer product, and is proposed to be promoted in places where improvement in sanitation management is needed, for example in Uganda’s capital Kampala. However, Uganda and most of Africa is perceived as a faecofobic area, i.e. where faeces are stigmatized and guarded by taboos, and there is lacking information regarding Ugandan farmers’ p

To plough or not to plough? : an investigation into what influences farmer decision making regarding the adoption of conservation agriculture

Agriculture is necessary for providing nutrition to a growing global population. However, many unsustainable agricultural practices contribute to climate change, cause local pollution and disrupt natural biological and nutrient cycles. Conservation agriculture (CA) is one of the many practices that have been proposed to meet the challenge of sustainable agricultural production. CA aims to restore

Decoding of individuated finger movements using surface EMG and input optimization applying a genetic algorithm.

In this paper we present surface electromyographic (EMG) data collected from 16 channels on five unimpaired subjects and one transradial amputee performing 12 individual finger movements and a rest class. EMG were processed using a traditional Time Domain feature-set and classifiers: a Linear Discriminant Analysis (LDA) a k-Nearest Neighbors (k-NN) and Support Vector Machine (SVM). Using continuou

Perception of Control Over Eating After Bariatric Surgery for Super-Obesity-a 2-Year Follow-Up Study

Physiological and psychosocial factors might contribute to differences in weight loss, eating behaviour and health-related quality of life (HRQoL) after bariatric surgery. The aim of this study was to investigate how perceived control over eating changes after bariatric surgery and whether it affects outcome in super-obese patients. In a retrospective analysis of a prospective study (n = 60), 49 p

Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer

Popular Abstract in Swedish Cancer är ett laddat ord, och för de flesta av oss är cancern inte längre bort än hos en nära släkting eller vän. Trots den gemensamma benämningen, är cancer är inte bara en sjukdom, utan ca 200 olika som alla har gemensamt att cellerna börjar dela sig okontrollerat. Cancer är väldigt vanligt och uppskattningsvis kommer var tredje person att drabbas av cancer under sin Early diagnosis and reliable prognosis and treatment prediction of breast cancer will ultimately lead to a decreased mortality rate. This can be achieved by identification of prognostic and treatment predictive biomarkers, and by understanding the mechanisms behind early changes in the breast. The cell cycle is a closely controlled process, involving multiple components with regulation on several

"Det blir nog bättre för barnen..." Slutrapport i utvärderingen av nationell försöksverksamhet med barnahus 2006-2007

Rättssociologiska enheten har haft uppdraget att utvärdera försöksverksamheten med barnahus för barn som utsatts för brott. Socialtjänst, sjukvård och rättsvårdande myndigheter ska samverka under ett tak, med målsättningen att barnanpassa utredningar och undvika att barn i onödan utsätts för upprepade kontakter med olika myndigheter. Utredningarnas kvalitet ska höjas för att ge bättre underlag för

No title

There are several characters with a brief appearance in the history of the drama, thus having an apparent minor significance in designing the play. They seem to be mere “working tools” for the playwright. However when relating them to the major issues of the literary product and if integrating them in a larger vision of the whole creation of the author their significance and role can be outlined i

A web-based interactive virtual environment for mobile phone customization

With globalization, more and more companies are becoming multisited. Efficient and timely collaboration and communication among the development team members become critical for product success. This paper proposes a web-based virtual environment for mobile phone customization, named VMPDS (Virtual Mobile Phone Design Space). The features of this system include the combination of web technology and

Nonequilibrium Green's Function Model for Simulation of Quantum Cascade Laser Devices Under Operating Conditions

A simulation scheme based on nonequilibrium Green's functions for biased periodic semiconductor heterostructure devices is presented in detail. The implementation can determine current and optical gain both for small and large optical fields. Specific results for superlattices, quantum cascade lasers, and quantum cascade detectors are shown which demonstrate the capabilities of the approach.

Adaptive immune responses in atherosclerosis - or how to prolong the use of your yellow socks

Popular Abstract in Swedish Drygt en tiondel av Sveriges befolkning lider av hjärt-kärlsjukdom som också är den vanligaste dödsorsaken. Många av de akuta sjukdomstillstånden orsakas av att en bit inflammerad blodkärlsvävnad bryts loss från sitt fäste i något av de stora blodkärlen, färdas med blodet och täpper till blodflödet i mindre blodkärl. Detta leder till syrebrist och celldöd nedströms om dAbstract Atherosclerosis is a multifactorial disease, but an unbalanced immune system plays a critical role in the disease development. A common theory states that a continuous stress to the vascular vessel wall initiates a repair process that however is insufficient to completely heal the tissue. This imbalance is associated with accumulation of cholesterol, which is an essential component of ce

Metaphors and Norms - Understanding Copyright Law in a Digital Society

Popular Abstract in Swedish Vad är det med upphovsrätten som inte fungerar i det digitala samhället? Vad är det som gör att miljoner människor just i fallet med fildelning tycker att det är okej att bryta mot lagen? Och, sett från det omvända perspektivet, vad är det som gör att lagen inte klarar av att anpassa sig efter de nya digitala praktikerna? Varför denna inlåsning och detta tillbakablickanThis is a compilation thesis in the sociology of law, which analyses copyright law in three steps; the legal norms, the social norms and the underlying conceptions in their metaphorical representation. These three steps assist in answering the overarching question: "How do legal and social norms relate to each other in terms of the conceptions from which they emanate or by which they are construct

The complementary use of IS technologies to support flexibility and integration needs in budgeting

In business controllers’ work on budgeting, considered as a classic decision-making process in organisations, it is consistently indicated that enterprise resource planning (ERP) systems, business intelligence (BI) and spreadsheets are commonly applied to assist the process. An academic research contribution on this topic is few. Most available research concentrates on ERP systems but it mentions

Sialoadhesin-Positive Macrophages Bind Regulatory T Cells, Negatively Controlling Their Expansion and Autoimmune Disease Progression

An important regulatory suppressive function in autoimmune and other inflammatory processes has been ascribed to CD4(+) Foxp3(+) regulatory T cells (Tregs), which requires direct cell-cell communication between Tregs, effector T cells, and APCs. However, the molecular basis for these interactions has not yet been clarified. We show here that sialoadhesin (Sn), the prototype of the siglec family of