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Carbon monoxide (CO) poisoning is a leading cause of environmental poisoning in the United States and can impair cellular metabolism through both hypoxia and direct mitochondrial toxicity, particularly via inhibition of cytochrome c oxidase (Complex IV, CIV). In this study, we performed a comprehensive assessment of the cerebral metabolic response to CO exposure in a swine model. Twenty-nine swine
Heavy-duty trucks, especially those used in urban areas, are responsible for a disproportionally large share of the external costs of the transportation sector. Policy instruments that target these trucks could thus be efficient measures to reduce negative impact from the traffic sector. This paper presents how heavy-duty trucks operated in Sweden’s two largest cities, Gothenburg and Stockholm, in
Childhood cancer aetiology is poorly understood and is considered to originate in utero and early postnatal life. In this study, we investigated perinatal characteristics as potential risk factors by performing a population-based case-control study, including 1340 cancer cases diagnosed < 19y and born between 1989–2021 in southern Sweden, and 13400 controls matched by sex, year, and municipality o
Rapporten analyserar finansieringen av den offentliga välfärden i Skåne inom ramen för ett decentraliserat system där kommuner och regioner har ett omfattande ansvar för många välfärdstjänster. Finansieringen baseras huvudsakligen på beskattning av förvärvsinkomster, vilket innebär att systemets stabilitet är nära kopplad till utvecklingen av arbetsmarknaden samt skattebasens storlek och fördelnin
Protein-losing enteropathy (PLE) is an uncommon and often underrecognized manifestation of lymphoproliferative disorders and may be difficult to diagnose when conventional gastrointestinal investigations are unrevealing. We present an 82-year-old woman with recurrent hospital admissions initially spanning six months for diarrhea, weight loss, peripheral edema, and persistent hypoalbuminemia. Initi
Background – Air–liquid interface (ALI) cell culture systems have improved the study of host-pathogen interactions in respiratory infections. However, most ALI models lack immune components, limiting their ability to capture epithelial–immune crosstalk. To address this, we developed a dual-cell ALI model incorporating human peripheral blood monocyte-derived macrophages beneath differentiated airwa
We consider the balayage of a measure μ defined on a domain Ω onto its boundary ∂Ω. Assuming that Ω has a corner of opening πα at a point z₀ ∈ ∂Ω for some 0 < α ≤ 2 and that dμ(z) ≅ |z - z₀|²ᵇ⁻² dz² as z → z₀ for some b > 0, we obtain the precise rate of vanishing of the balayage of μ near z₀. The rate of vanishing is universal in the sense that it only depends on α and b. We also treat the case w
Symbioses can be vital on islands, where low species diversity leaves few alternative partners and the failure of associations can cascade into broader community collapse. Key to the functioning of many island ecosystems is the rainforest tree, Pisonia grandis (pisonia). Pisonia attracts nesting seabirds whose guano delivers intense nutrient pulses that fuel coral reef ecosystems. Symbiotic mycorr
The scale of the 21st-century urban housing challenge has prompted state actors in both the Global North and South to adopt increasingly interventionist approaches to ‘affordable’ housing production. This article draws on research in six cities (Shanghai, Nairobi, Paris, Casablanca, Salford and Rome) to discuss the changing relationship between housing, finance and the state through a global compa
The next generation wireless systems will face stringent new requirements, including ultra-low latency, high data rates and enhanced reliability. Large Intelligent Surfaces, is one proposed solution that has the potential to solve these high demands. The real-life deployment of such systems involves different design considerations with non-trivial trade-offs. This paper investigates the trade-off
Strategies that enable ignition of the low cetane alcohol fuels (methanol and ethanol) include intake heating (direct or via hot residual trapping), increased compression ratio (CR), multi-injection strategies, ignition enhancers, and active prechambers. The literature consistently shows alcohol compression ignition (CI) is more efficient than diesel at high loads irrespective of ignition strategy
Single-stranded RNA viruses co-assemble their capsid with the genome, and variations in capsid structures can have significant functional relevance. In particular, viruses need to respond to a dehydrating environment to prevent genomic degradation and remain active upon rehydration. Theoretical work has predicted low-energy buckling transitions in icosahedral capsids, which could protect the virus
The fourth United Nations High-Level Meeting on the Prevention and Control of Noncommunicable Diseases (NCDs) and Promotion of Mental Health and Well-Being developed a timely Political Declaration intended to accelerate progress among Member States towards the targets of Sustainable Development Goal 3.4. The Declaration emphasises appropriate cross-cutting actions for prevention and control of NCD
In a context where scientific communication is caught be-tween the for-profit motives of large publishers and the need for democratized knowledge, the journal Ecosistemas reaffirms its commitment to a publication model that is, above all, by the scientific community and for the scientific community. We are not only consolidating our vision, but also taking firm steps toward a new stage of mod
Background: Climate change poses an escalating threat to global brain health and is increasingly linked to stroke incidence, outcomes, and inequities in prevention and treatment. This World Stroke Organization scientific statement summarizes current evidence on the associations between stroke and the environmental variables exacerbated by climate change, with a focus on risk and outcomes. Methods:
Machine learning algorithms for myoelectric pattern recognition require substantial user-specific training data, limiting broader applications of electromyography (EMG) in human–computer interfacing. Here, we present a framework for EMG-mediated motor intent decoding designed to function for new users without collecting user-specific training data. We introduce a Transformer-based architecture, te
Most forensic psychiatric patients are diagnosed with schizophrenia or schizoaffective disorder. Psychotherapy is recognized as an important part of treatment for this patient population, yet no clinical guidelines exist. This mixed-method systematic review aimed to evaluate the scope, quality, and findings of psychotherapy research involving this population. Following the Joanna Briggs Institute
Introduction: Oxidating fat as an energy substrate requires more oxygen than utilizing carbohydrates and can be acutely increased by hyperoxia. Therefore, substrate utilization may affect endurance performance and gas consumption in divers, but previous research is limited. This study aimed to evaluate changes in maximal fat oxidation (MFO) in navy divers during training. Methods: Seven explosive
