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Patch-clamp recordings and glucagon release measurements were combined to determine the role of plasma membrane ATP-sensitive K+ channels (K-ATP channels) in the control of glucagon secretion from mouse pancreatic alpha-cells. In wild-type mouse islets, glucose produced a concentration-dependent (half-maximal inhibitory concentration [IC50] = 2.5 mmol/l) reduction of glucagon release. Maximum inhi
This thesis concerns economic aspects of ageing and investigates incentives and outcomes related to this process. The thesis is a collection of five essays. An introductory chapter provides an overall economic perspective of ageing. Essay 1 (ch 2) examines mortality risks via duration analysis of widowed individuals in Scania, Sweden during the 19th century. The findings are qualitatively in line
Popular Abstract in Swedish Inom många olika fält hyllas dialogen. Det finns en stark och utbredd tro, främst i det västerländska samhället, att lyckas man bara upprätta en dialog kan man planera i samförstånd och lösa problem. Människor talar med varandra för att förstå, hjälpa varandra och för att skapa gemensamma värden och målsättningar. I studiet av samtal upptäcker man emellertid snabbt att In the spring of 1997 a group of parents of deaf and hearing-impaired children and representatives of a special school in the south of Sweden began to hold formally arranged meetings in order to start a “dialogue”. This particular form of collaboration became the focus of this study. The meetings lasted two to three hours and I attended seventeen of them. The transcriptions of those meetings form
On contemporary rock'n roll movies as pastische.
According to the so-called Substituted Judgment Standard, a surrogate decision maker, acting on behalf of an incompetent patient, ought to make that health care decision which the patient would have made, had the latter been competent. The most common way of justifying the Substituted Judgment Standard is to maintain that this standard extends patients’ opportunities for self-determination to situ
Why, how, and with what consequences do national governments delegate political authority to supranational institutions? Contrary to the static conceptions of delegation that dominate the existing literature, this article adopts a dynamic approach, where the stages of the delegation process are integrated into a coherent rational institutionalist framework. With demonstrations from the case of the
ATP is released as a cotransmitter together with catecholamines from sympathetic nerves. In the heart ATP has been shown to cause a pronounced positive inotropic effect and may also act in synergy with β-adrenergic agonists to augment cardiomyocyte contractility. The aim of the present study was to investigate the inotropic effects mediated by purinergic P2 receptors using isolated mouse cardiomyo
We have previously described a new and simple method for nerve repair in which continuous longitudinal polyglactin sutures alone are used to bridge limited nerve defects in rats. Here we examined whether such sutures could be used to deliver a growth-promoting substance, triiodothyronine (T3), and enhance regeneration of the rat sciatic nerve. Sutures were pretreated in highly concentrated solutio
In this paper, the IWA anaerobic digestion model No. 1 (ADM1) is applied to two case studies from contract work on industrial treatment plants. The first was the assessment of acid addition for pH decrease and avoidance of calcium carbonate (CaCO3) precipitation in a paper mill fed UASB. The simulation work found, with a high degree of confidence, that acid dosing was neither economical for pH con
A summary of a study covering both modelling and control of a drum boiler is presented. A systematic approach to the modelling problem - numerical modelbuilding - is introduced. This technique was applied to the modelling of the drum of the boiler. The dynamics of different order models were compared. The load disturbances were modelled from measurements as a stationary stochastic process with rat
The effects of intravenously infused CGRP on regional blood flows and vascular resistance in the upper respiratory tract, the middle ear, and the inner ear were studied in cats. CGRP caused a pronounced vasodilation and an increase in blood flow of the respiratory mucosa and structures of the middle ear. The substance did not affect the blood flows of the cochlea and the vestibular organ in the in
