Filetype
This prospective study was initiated in 1993 with the aim to study late effects and responses to antiviral therapy in a cohort of hepatitis C virus (HCV)-infected patients. A total of 195 patients were included from 12 centers. In all, 134 patients had undergone allogeneic and 61 autologous hematopoietic SCT (HSCT). The median follow-up from HSCT is currently 16.8 years and the maximum 27.2 years.
Pancrustacea (Hexapoda plus Crustacea) display an enormous diversity of eye designs, including multiple types of compound eyes and single-chambered eyes, often with color vision and/or polarization vision. Although the eyes of some pancrustaceans are well-studied, there is still much to learn about the evolutionary paths to this amazing visual diversity. Here, we examine the evolutionary history o
Typically a donor-acceptor (D-A) design strategy is used for engineering the bandgap of polymers for solar cells. However, in this work, a series of alternating D-A(1-)D-A(2) copolymers PnTQTI(F) were synthesized and characterized with oligothiophenes (nT, n = 1, 2, 3) as the donor and two electron-deficient moieties, quinoxaline and isoindigo, as the acceptors in the repeating unit. We have studi
Methods to generate spin-polarized electronic states in nonmagnetic solids are strongly desired to enable all-electrical manipulation of electron spins for new quantum devices(1). This is generally accepted to require breaking global structural inversion symmetry(1-5). In contrast, here we report the observation from spin- and angle-resolved photoemission spectroscopy of spin-polarized bulk states
A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7 TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb(-1) to 4.8 fb(-1). Higgs boson decays into oppositely-ch
Background and purpose - A shortened tibial stem could influence the early prosthetic fixation. We therefore compared the short stem to the standard-length stem using radiostereometric analysis (RSA) as primary outcome measure. Patients and methods - 60 patients were randomized to receive a cemented Triathlon total knee arthroplasty (TKA) with a tibial tray of either standard or short stem length.
In this paper, the problem of detecting target in system-dependent clutter (SDC) background with a single observation from the test cell is researched. Classical detectors, such as the generalized likelihood ratio detectors (GLRDs) and the adaptive matched filters (AMFs), etc., usually deal with the clutter and the noise as a whole. The low rank detectors (LRDs) make use of the low rank property o
In spring 1986, Lindsay Anderson appeared in a television programme on British cinema. This was part of a series of three under the heading British Cinema: Personal View, produced by Thames Television. Anderson’s contribution, Free Cinema 1956–? An Essay on Film by Lindsay Anderson, was written and directed by him. He was also the star of the programme, providing a lecture on the history of Britis
Protein conformational dynamics can be critical for ligand binding in two ways that relate to kinetics and thermodynamics respectively. First, conformational transitions between different substates can control access to the binding site (kinetics). Secondly, differences between free and ligand-bound states in their conformational fluctuations contribute to the entropy of ligand binding (thermodyna
Streptococcus pyogenes is an important human pathogen that causes a variety of diseases including life-threatening invasive diseases, such as toxic shock and deep tissue infections. Although S. pyogenes are classically considered extracellular pathogens, a clinical significance of an intracellular source has been emphasized. In patients with deep tissue infections, an intracellular reservoir of S.
This study investigated how visitors and staff in community-based activity centers in Sweden perceived the psychosocial atmosphere and whether this could be explained by the centers' orientation (work-oriented versus meeting place-oriented centers). Eighty-eight visitors and 37 staff members at three work-oriented and three meeting place-oriented centers participated. The Community-oriented Progra
Background: Only about half the studies that have collected information on the relevance of women's height and body mass index to their risk of developing ovarian cancer have published their results, and findings are inconsistent. Here, we bring together the worldwide evidence, published and unpublished, and describe these relationships. Methods and Findings: Individual data on 25,157 women with o
Genome editing via CRISPR/Cas9 has rapidly become the tool of choice by virtue of its efficacy and ease of use. However, CRISPR/Cas9-mediated genome editing in clinically relevant human somatic cells remains untested. Here, we report CRISPR/Cas9 targeting of two clinically relevant genes, B2M and CCR5, in primary human CD4(+) T cells and CD34(+) hematopoietic stem and progenitor cells (HSPCs). Use
Between 2008 and 2010, Lund University took part in three international benchmarking projects, E-xcellence+, the eLearning Benchmarking Exercise 2009, and the First Dual-Mode Distance Learning Benchmarking Club. A comparison of these models revealed a rather high level of correspondence. From this finding and from desktop studies of the current discourse regarding e-learning, a conceptual framewor
Angiomatoid fibrous histiocytoma (AFH) is an uncommon and mostly indolent soft tissue neoplasm, which usually occurs in the subcutaneous tissue of the extremities in children and young adults. Although the histologic features of AFH are well established, reports of its cytomorphology are very limited. This report characterizes the cytomorphologic features of five cases of AFH, with correlation to
To obtain better fluid mixing and higher heat transfer in the low Reynolds number regime, various wavy fins are employed in heat sinks (heat exchangers) for electronic cooling applications. However, it was reported in previous works that in the low Reynolds number regime there are no remarkable differences in the thermal performance of a straight-plate and a wavy-wall channel. In this study, the c
