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Texten fokuserar några valsituationer efter besked om obotlig cancer. Sådant som: Vem ska vi berätta för? Acceptera behandling som kemoterapi eller ej? Ta livet av sig eller ta kampen? Döva sina känslor med medicin eller sträva på med hjälpmedel som syrgas och rullator?
To improve the accuracy and transferability of molecular mechanics force fields, one needs a simple physical description of intermolecular polarization based on quantum chemistry. Ideally, in the quantum-chemical description, each molecule is treated separately and the interactions with other molecules are included as a perturbation. We propose a simple formulation of this perturbation, viz. to mo
HLA DR4-DQ8 and DR3-DQ2 haplotypes account for 89% of newly diagnosed cases of type 1 diabetes (T1D) in Sweden. The presence of a single copy of DQ6 confers protection. The aim of the present study is to evaluate whether the risk conferred by high risk HLA DR and DQ to T1D is similar in all regions of Sweden and see whether there are any significant regional differences. The subjects comprised 799
Kollektivt författad skrivelse, "För ett bättre Lunds universitet nu", om villkoren för unga forskare vid LU, publicerad i LUM nr 7/2015, s. 34 under rubriken "Ta vara på unga forskares kapacitet!".
Filmen Four Lions väckte stor uppmärksamhet och lockade storpublik i Storbritannien trot, eller tack vare, att den behandlade frågan om islamistisk terrorism med humorn som vapen-
Arthritides are musculoskeletal diseases, which predominantly affect the joints e.g. osteoarthritis (OA) and rheumatoid arthritis (RA). Modern treatment strategies include early detection and careful monitoring of the disease course. Close monitoring is also the basis for individualized treatment. Monitoring should be done using methods reflecting different aspects of the disease to get a broad pe
This paper reports on a case study, which investigated energy management and environmental management at a large-scale research facility. The author used the perspective of the managed personnel rather than the management, the entity or the management system. The focus of the research was on interpretation of work, particularly how employees' perceptions of priorities were affected by management i
Leuprolide is a gonadotropin-releasing hormone (GnRH) analog which has been shown to reduce symptoms in patients with irritable bowel syndrome (IBS) and chronic intestinal pseudo-obstruction (CIPO). The mechanism is not known, but one hypothesis is through down-modulation of luteinizing hormone (LH) secretion, a hormone whith antagonistic effect on gastrointestinal motility. However, presence of L
Six glycoside hydrolase (GH) family 13 members, classified under the polyspecific neopullulanase subfamily GH13_20 (also termed cyclomaltodextrinase) were analysed. They originate from thermophilic bacterial strains (Anoxybacillus flavithermus, Laceyella sacchari, and Geobacillus thermoleovorans) or from environmental DNA, collected after in situ enrichments in Icelandic hot springs. The genes wer
Background: To estimate cardiovascular disease (CVD) mortality in relation to obesity and gender. Methods: Data from 11 prospective cohorts from four European countries including 23 629 men and 21 965 women, aged 24 to 99 years, with a median follow-up of 7.9 years were analyzed. Hazards ratios (HR) for CVD mortality in relation to baseline body mass index (BMI), waist circumference (WC), waist-to
Two splice sites on the human papillomavirus type 16 (HPV-16) genome are used exclusively by the late capsid protein L1 mRNAs: SD3632 and SA5639. These splice sites are suppressed in mitotic cells. This study showed that serine/arginine-rich protein 30c (SRp30c), also named SFRS9, activated both SD3632 and SA5639 and induced production of L1 mRNA. Activation of HPV-16 L1 mRNA splicing by SRp30c re
Objective. The information concerning the morbidity and mortality of hereditary hemochromatosis is based primarily on clinical cohorts of symptomatic patients. The major aim of this study was to analyze the long-term prognosis for Swedish patients with this condition, with respect to both clinical features and survival, in relation to the route by which the disease was detected. Patients and metho
We assessed how zooplankton (copepods) handle the simultaneous threats of predators and ultraviolet (UV) radiation and whether they respond with changes in pigmentation, vertical migration, or both. We found weak vertical migration among copepods in response to UV stress, and this response was not apparently influenced by predation risk. Exposure to high levels of UV radiation caused copepods to r
We investigate the potential of using previewed wind speed measurements for damping wind turbine fore-aft tower oscillations. Using recent results on continuous-time H2 preview control, we develop a numerically efficient framework for the feedforward controller synthesis. One of the major benefits of the proposed framework is that it allows us to account for measurement distortion. This results in
Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable presentations, course and prognosis. We sought to develop evidence-based recommendations addressing the major issues in the management of SLE. Methods: The EULAR Task Force on SLE comprised 19 specialists and a clinical epidemiologist. Key questions for the management of SLE were compiled using the Delphi technique. A
The quality of powder is determined by its functionality such as dissolution, encapsulation and flowability. The functionality of powder is in turn determined by their primary properties such as morphology and composition which need to be studied. Hence morphology and surface composition has been largely investigated in spray dried powders and individually dried particles. On the contrary, there i
