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The aim of this study was to evaluate whether biomarkers of environmental tobacco smoke exposure [i.e, 4-aminobiphenyl-hemoglobin (4-ABP-Hb) adducts] were predictive of the risk of tobacco-related cancers and diseases. We did a case control study nested within the European Prospective Investigation into Cancer and Nutrition, involving 190 controls and 149 cases (incident cancer of the lung, bladde
Popular Abstract in Swedish Okontrollerad proliferation och invasion är två viktiga egenskaper i tumörutveckling och tumörprogression. Tidigare studier har visat att invaderande tumörceller i kolorektalcancer har låg proliferation parallellt med en uppreglering av tumörsuppressorn p16. Vi undersökte p16-uttrycket och proliferation i basalcellscancer och skivepitelcancer i huden, tumörer som är lokUncontrolled proliferation and invasion are two characteristics in tumour development and progression. Previous studies have shown that invading tumour cells in colorectal cancer have low proliferation in parallel to upregulation of the tumour suppressor p16. We set out to detail the p16 expression and proliferation in basal cell carcinoma and squamous cell carcinoma of the skin, tumours that are
Intravenous infusions of 750 and 1000 ml 2.2% sodium citrate were given over a 60 min period to 17 pigs to study its effect on aortic pressure, electrocardiogram, ionised calcium, and citrate clearance. In group 1 (seven pigs) the animals did not receive calcium and the median survival time was 30 min (range 20-70 min). In groups 2 and 3 (five in each group) the pigs were treated with calcium chlo
Filmrecension av Jean-Jacques Annauds Enemy at the Gates.
Anaerobic digestion would enable the energy potential of agricultural crop residues such as ley crops and sugar beet tops to be harnessed in Sweden. In the present study, the financial prospects of single-stage fed-batch high-solids digestion on three different scales, 51, 67, and 201 kW, were calculated on the basis of experimental results and observations. In addition to scale, the effects of me
Epitopes found on Mucin-1 are differentially expressed on tumour versus normal tissue. Such epitopes have also been shown to have a potential in immunotherapy and tumour detection. The major epitope explored in this context is located within the variable number of tandem repeats. It has however recently been demonstrated that this epitope exists in several sequence variants. The standard sequence
A classical linear programming approach to optimization of flow or transportation in a discrete graph is extended to hybrid systems. The problem is finite-dimensional if the state space is discrete and finite, but becomes infinite-dimensional for a continuous or hybrid state space. It is shown how strict lower bounds on the optimal loss function can be computed by gridding the continuous state spa
We investigated the potential use of Al2O3:C for medical proton dosimetry. Detector crystals coupled to fiber-optic cables were irradiated in proton beams with energies from 10 to 60 MeV. The key finding is that the initial intensity of the optically stimulated luminescence (OSL) signal is energy independent for small detectors (<0.5mm) and relatively small doses (<0.3Gy). This feature is related
The mixed-valence dinuclear ruthenium complex [Ru2(bpmp)(-OAc)2]2+ (where bpmp is the phenolate anion of 2,6-bis[bis(2-pyridylmethyl) aminomethyl]-4-methylphenol, H-bpmp) has been studied by UV-Vis-NIR, IR, and EPR spectroscopic and electrochemical techniques. The Ru2II,III complex undergoes reversible one-electron reduction (E1/2 = -0.61 V vs Fc+/0) and oxidation (E1/2 = 0.09 V vs Fc+/0), resulti
I denna bok redovisas ett projekt i Lund (kv. Bollen) vars syfte var att visa att det med tillgänglig teknik och till rimliga kostnader går att bygga bostäder som uppfyller högt ställda krav på ljudkomfort. De uppställda kraven, problembeskrivningar, valda lösningar, kostnadsförändringar samt de utförandetekniska konsekvenserna redovisas detaljerat.
