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Through Arctic amplification, global climate change is projected to disproportionally affect high-latitude environments. Additionally, the geographical heterogeneity and complex terrain of mountains promote climate-driven ecological change on fine spatial scales. We used a high-resolution convection-permitting regional climate model (HCLIM) and a state-of-the-art dynamic vegetation model (LPJ-GUES
Public debate is central to most theories of democracy, yet few cross-national studies have examined its association with democratic satisfaction. This article identifies three features of national public spheres – pluralism, information, and respect – and presents annual measures of these features for 175 countries from 2000 to 2020. Among electoral democracies, pluralism remained stable, but the
The Telychian Age (Llandovery, Silurian) is marked by significant radiation among marine organisms, a faunal turnover, and palaeoenvironmental changes, collectively known as the Valgu Bioevent (Valgu BE), Valgu Carbon Isotope Excursion (Valgu CIE), and the Valgu Oxygen Isotope Excursion (Valgu OIE). However, the environmental drivers of these changes remain debated. Here we investigate the middle
The Self-Concordance Model posits that autonomously motivated goal pursuit is a primary driver of well-being, yet standard measurement practices often conflate the presence of autonomy with the absence of external pressure via relative difference scores. Using a high-powered dataset (N = 429), this study tested a Balance Model against an Autonomous-Primary Model. Using Bayesian structural equation
Background: Individuals with diabetes have an increased risk of cardiovascular disease, infection, hospitalization, and premature mortality. However, less is known about how diabetes shapes the broader pattern of emergency department (ED) presentations, acute care use, clinical complexity, and short-term mortality in an unselected ED population. We aimed to describe ED presentation patterns and ou
DNA methylation deregulation is an essential feature of tumor biology, influencing cancer formation and pathogenesis. Analyses of DNA methylation in bulk cancer specimens are challenging due to the high data dimensionality, noise, and mixture of different cell types. Here, we characterized methylation dynamics in cancer by investigating the variance structure of bulk tumor DNA methylation data thr
BACKGROUND: Pheochromocytomas and paragangliomas (PPGLs) are rare and mostly non-metastatic tumors originating from adrenal medulla and paraganglia. Metastatic PGLs have a worse prognosis, but currently, there are no established criteria to determine PPGL metastatic potential.AIM: The aim of this study was to investigate whether SDHB and CDK1 expression is associated with metastatic capacity in PP
This doctoral research develops Ancestral Dramaturgies, a decolonial, practice-based methodology for investigating how personal, collective, and more-than-human histories can be activated, encountered, and transformed through dramaturgical and performative practice. The research emerges from my situated trajectory as a diasporic, Queer, non-binary artist and researcher of colour engaging with migr
Recent research suggests that long-term economic prosperity depends less on rapid growth than on reducing the frequency of economic shrinking. This paper investigates why episodes of economic shrinking declined in 33 Latin American and Caribbean countries between 1970 and 2016; a region that has received comparatively little attention in the emerging literature on economic shrinking. Using a theor
Background: Uterine sarcomas are rare and high-quality evidence regarding optimal treatment is limited and difficult to produce. Methods: A total of 618 patients with uterine sarcoma were identified in the Swedish Quality Registry for Gynecologic Cancer (SQRGC) from 2010 to 2020. Survival was analyzed according to stage, histology and treatment modality. Results: The incidence of uterine sarcoma w
Obesity-related type 2 diabetes (T2D) is currently defined by insulin resistance and impaired insulin secretion. Sulfonylureas, thiazolinediones, and insulin are effective at lowering glycemia yet have not consistently translated into improved long-term outcomes. In contrast, recent interventions often produce metabolic benefits that exceed expectations based on glucose lowering alone. These contr
This article examines the role of private defence investment as part of the efforts to define the scope and meaning of EU social sustainability, at a time of increased EU investment interest in the aerospace and defence industry (A&D). One of the central questions posed by private investors, civil society and international legal scholars alike is, in fact, whether investment in the production
This paper investigates collaborative mobile edge computing (MEC) servers for large language model (LLM) inference under soft deadline constraints. In this system, to improve the quality of service, computations are expected to be completed within their deadlines. However, due to dependencies among tasks or subtasks, any missed deadline can lead to catastrophic consequences for the entire request.
In this thesis machine learning applications to modern particle accelerators are developed and tested at a number of facilities. The focus is on improving and advancing longitudinal diagnostics, with a major project focusing on non-destructive predictions of beam distributions in longitudinal phase space. Applications are developed using data collected from MAX IV, FERMI, SwissFEL and FLASH. Beyon
ABSTRACT The efficacy of cryosurgery for skin cancers is believed to depend on thaw time, which may be influenced by the presence of adrenaline in local anaesthetics due to its vasoconstrictive effects. This is the first study to perform detailed, non-invasive temperature measurements using infrared (IR) thermography during cryosurgery for basal cell carcinomas (BCCs), evaluating the impact of adr
Africa's historical borderlands are persistently associated with low levels of economic development. This paper examines how these regions respond to development interventions, analysing whether the long-run development advantage associated with colonial Christian missions persists near historical homeland borders. Combining georeferenced data on 3,365 pioneering mission stations with high-resolut
BACKGROUND: Current diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) require history of orthostatic intolerance and heart rate elevation of ≥30 bpm in adults or ≥40 bpm in adolescents during a 10-minute standing or a tilt table test. Many patients with orthostatic intolerance experience autonomic dysfunction and functional impairment despite not meeting the required heart r
Despite the prevalence of slavery in world history, our understanding of its persistence remains limited. Most previous studies focus primarily on slavery as a labour contract, indistinguishable from other coercive arrangements such as serfdom. More recent literature on slavery in the United States shows that enslaved people also played an important role as financial instruments. In this article,
The economic history of British colonialism in Southern Africa is defined by three interrelated dynamics: the initial expansion driven by chartered companies, a substantial influx of European settlers, and the establishment of racially segregated, unequal Neo-European societies. In this chapter, we show how the discovery of minerals in the nineteenth century radically reshaped the economic and soc
Understanding the determinants that influence parents’ decisions to participate with their infants in primary prevention trials is essential for achieving representative study samples and ensuring the generalizability of outcomes. We analyzed quantitative and qualitative data collected from infants eligible for the Primary Oral Insulin Trial (N= 2,750) or the Supplementation with B. INfantis for M
