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The aim of this study was to design a clinical vocal loading task (VLT) and to track vocal loading and recovery in voice-healthy subjects.

Background: Possible synergism between female sex hormones and vitamin D on periodontitis pathology has not been assessed. Here, we investigate effects of estrogen, progesterone and vitamin D on periodontitis in a population-based sample and use cell studies to explore mechanistic explanations of the population-based findings. Methods: The epidemiological analysis utilizes cross-sectional data fro

The preparation and characterization of mixed-mode adsorbents for a typical separation purpose are of great importance in bioseparation areas. In this work, we prepared a new monolithic cryogel with a combination of ion-exchange and hydrophobic functions by employing benzyl-quaternary amine groups. The fundamental cryogel properties, protein equilibrium adsorption isotherm and chromatographic adso

The prevalence of hippocampal lesions such as hippocampal infarcts have not been studied in detail even though hippocampal alterations are known to be associated with various clinical conditions such as age-related degenerative disorders and epilepsy. Methods: Here we defined the hippocampal infarcts and assessed the prevalence of this lesion in large unselected population of 1,245 subjects age ra

The rs738409 C > G single-nucleotide polymorphism in PNPLA3 leads to a missense mutation (I148M) which increases liver fat but does not cause insulin resistance. We hypothesised that patients with non-alcoholic fatty liver disease (NAFLD) due to the PNPLA3 variant ('PNPLA3 NAFLD'aEuro parts per thousand= PNPLA3-148MM) do not have adipose tissue (AT) inflammation in contrast with those with NAFLD d

One billion vulnerable subsistence farmers across the global south depend on risky livelihoods in need of adaptation to climate change impacts. Simultaneously, their aggregated emission of greenhouse gases from land use and fuelwood consumption is substantial. Synergies between adaptation to climate change and mitigation should therefore be actively promoted. In the context of poverty, such synerg

Drawing from ethnographic data from 48 households in four villages in rural Anhui, this study explores how two practices known for upholding son preference are affected by rural–urban out-migration, with a particular focus on the division of labour in agricultural work and patrilocality. The study deploys the concepts of an intergenerational contract and the “unsubstitutability” of sons and finds

Psychiatric symptoms such as depression and anxiety are important clinical features of Huntingtons disease (HD). However, the underlying neurobiological substrate for the psychiatric features is not fully understood. In order to explore the biological origin of depression and anxiety in HD, we used a mouse model that expresses the human full-length mutant huntingtin, the BACHD mouse. We found that

The present study investigates the dental work in terms of time distribution and mechanical exposure in value-adding work (VAW) and non-VAW. Further rationalisation of dental work would typically involve an increase in the proportion of VAW. Information on mechanical exposure within the classes of VAW and non-VAW may be used to predict possible implications of rationalisation. Sixteen dentists wer

To study differences in body mass index (BMI), waist-hip ratio (WHR), waist circumference (WC), sagittal abdominal diameter (SAD), waist-hip-height ratio (WHHR) and percent body fat in immigrants and Swedish-born men and women in two large population-based samples.

BACKGROUND: Muscle weakness in one or both upper limbs is common in persons with previous polio, but there is very limited knowledge how it influences daily life. OBJECTIVE: To assess muscle weakness and self-perceived disability of the upper limbs in persons with late effects of polio and evaluate their association. DESIGN: Cross-sectional study. SETTINGS: University hospital outpatient clini

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a devastating inherited disorder characterized by episodic syncope and/or sudden cardiac arrest during exercise or acute emotion in individuals without structural cardiac abnormalities. Although rare, CPVT is suspected to cause a substantial part of sudden cardiac deaths in young individuals. Mutations in RYR2, encoding the cardiac sa

The massive amount of genomic sequence data that is now available for analyzing evolutionary relationships among 31 placental mammals reduces the stochastic error in phylogenetic analyses to virtually zero. One would expect that this would make it possible to finally resolve controversial branches in the placental mammalian tree. We analyzed a 2,863,797 nucleotide-long alignment (3,364 genes) from

Resolving the spatial and temporal dynamics of gross primary productivity (GPP) of terrestrial ecosystems across different scales remains a challenge. Remote sensing is regarded as the solution to upscale point observations conducted at the ecosystem level, using the eddy covariance (EC) technique, to the landscape and global levels. In addition to traditional vegetation indices, the photochemical

PHENIX measurements are presented for the cross section and double-helicity asymmetry (A(LL)) in inclusive pi(0) production at midrapidity from p + p collisions at root s = 510 GeV from data taken in 2012 and 2013 at the Relativistic Heavy Ion Collider. The next-to-leading-order perturbative-quantum-chromodynamics theory calculation is in excellent agreement with the presented cross section result

Current European Association of Urology guidelines state that a PSA≥100 ng/ml at diagnosis indicates metastatic disease. The aim of the present study was to examine the association between PSA values ≥100 ng/ml at diagnosis, distant metastasis and prostate cancer-specific survival.

To improve the fatigue resistance of stainless steel sheet, it is a common practice to induce compressive residual stress in the surface through shot-peening or tumbling. Stress depth profiles obtained by tumbling of thin stainless steel tensile rods were analysed using laboratory and synchrotron X-Ray Diffraction (XRD). Both the non-destructive synchrotron and the laboratory XRD etch-depth profil

Upper lower Cambrian (provisional Cambrian Series 2) trilobites are described from three sections through the Shuangyingshan Formation in the Beishan area, northwestern Gansu Province, China. The trilobite fauna is dominated by eodiscoid and 'corynexochid' trilobites, together representing at least ten genera: Serrodiscus, Tannudiscus, Calodiscus, Pagetides, Kootenia, Edelsteinaspis, Ptarmiganoide

Large eddy simulation is performed to investigate air entrainment and mixing in diesel sprays with and without combustion. The Spray A case of the Engine Combustion Network (ECN) is considered in the study, in which liquid n-Dodecane is injected at 1500 bar through a nozzle of 90 mu m into a constant volume vessel with an ambient density of 22.8 kg/m(3) and an ambient temperature of 900 K. Primary