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Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) potently augment insulin response to glucose. It is less known what their effects are insulin clearance, which also contributes to peripheral hyperinsulinemia observed after administration of incretins together with glucose. The aims of this study were the quantification of C-peptide secretion and the evaluation
Lead has negative effect on cognitive functions in children. However, individuals differ in susceptibility. One possible explanation is a genetic predisposition. Polymorphisms in the B-aminolevulinic acid dehydratase (ALAD) and the vitamin D receptor (VDR) genes may modify lead metabolism and neurotoxicity, but information regarding the central nervous system is very limited. The aim of the study
Based on high-resolution spectra obtained during gravitational microlensing events we present a detailed elemental abundance analysis of 32 dwarf and subgiant stars in the Galactic bulge. Combined with the sample of 26 stars from the previous papers in this series, we now have 58 microlensed bulge dwarfs and subgiants that have been homogeneously analysed. The main characteristics of the sample an
The politics of European collaborative Big Science are inherently uncertain. The European Spallation Source (ESS) for materials science, planned to be built in Sweden with a collaborative European funding solution that was recently finalized is the most recent example. Sweden has so far invested around one billion SEK (&E110 million), taking a significant risk given these uncertainties and giv
Managing risk using an “all-hazards” and “whole of society”-approach involves extensive communication of risk descriptions among many stakeholders. In the present study we investigate how professionals working with disaster risk management in such contexts perceive the usefulness of different descriptions of risk. Empirical data from the Swedish disaster risk management system were used in an atte
Background: Pediatric intestinal biopsy procedures including considerable transpharyngeal manipulation of a wire-guided metal capsule require adequate sedation or anesthesia. This retrospective cohort study was designed to evaluate intravenous sedation with ketamine and low-dose midazolam in young children undergoing these procedures before and also after discharge from the hospital. Methods: A t
This article investigates whether public funds should support R&D and if so, how such support should be designed in order to be efficient and to comply with the legal requirements stated in EU law and in domestic budget law. The article puts the emphasis on tax expenditure and, in particular, on tax incentives. The findings show that Member States should only subsidize projects where the socia
Urban water management policy in Japan, with examples from Fukuoka city, is described and the potential for sustainability of Fukuoka's urban water system is discussed. A framework of the qualitative characteristics of a sustainable system (including social, environmental and economic factors) is developed and used in the analyses presented here. The Fukuoka example shows that technically advanced
Cement hydration needs water to proceed and if water is lost by drying, the hydration rate will decrease This can be of importance in cases when concrete surfaces are exposed to drying so that their strength development will be retarded We describe a method based on isothermal calorimetry to assess how the rate of cement hydration is influenced by removal of water (drying) at different times up to
Customers are important stakeholders for any company; yet, they seem not to be widely discussed in merger and acquisition research. This chapter synthesizes the current body of research on customers in mergers and acquisitions through presenting a systematic literature review. The chapter is based on a systematic literature review resulting from a search in EBSCO Host for any research item that re
Popular Abstract in Swedish Partiella differentialekvationerna} är kraftfulla verktyg som kan användas för att beskriva fysikaliska fenomen inom bland annat naturvetenskap, teknik, ekonomi och medicin. Listan med tillämpningar kan göras hur lång som helst: Partiella differentialekvationer kan beskriva hur en snöflinga bildas, hur strukturer deformeras när de utsätts för mekaniska krafter, hur blodSplitting methods are widely used as temporal discretizations of evolution equations. Such methods usually constitute competitive choices whenever a vector field can be split into a sum of two or more parts that each generates a flow easier to compute or approximate than the flow of the sum. In the research presented in this Licentiate thesis we consider dissipative evolution equations with vector
Purpose - The paper aims to explore the potential effects on logistic operations of implementing the Electronic Product Code Information Service (EPCIS) standard and radio frequency identification (RFID) technology to enable food traceability. A conceptual model for analysing supply chains according to EPCIS standard is also presented. Design/methodology/approach - A literature review was conducte
Insights into how exactly a fly powers and controls flight have been hindered by the need to unpick the dynamic complexity of the muscles involved. The wingbeats of insects are driven by two antagonistic groups of power muscles and the force is funneled to the wing via a very complex hinge mechanism. The hinge consists of several hardened and articulated cuticle elements called sclerites. This art
Perophoramidine, dehaloperophoramidine, and communesin F are structurally related alkaloids having intriguing polycyclic structures. A strategy for the synthesis of dehaloperophoramidine has been developed. In this synthesis all skeletal atoms and all functional groups required to reach the target molecule are incorporated early in the sequence. This approach led to the discovery of two novel subs
Let L be a proper differentiation invariant subspace of C-infinity (a, b) such that the restriction operator d/dx vertical bar L has a discrete spectrum Lambda (counting with multiplicities). We prove that L is spanned by functions vanishing outside some closed interval I subset of (a, b) and monomial exponentials x(k)e(lambda x) corresponding to Lambda if its density is strictly less than the cri
