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Increased incidence of prostate cancer has been reported in men exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD acts through the aryl hydrocarbon receptor (AhR), which interacts with the androgen receptor (AR). The AR gene contains a polymorphic CAG repeat that influences its transcriptional activity. We investigated the influence of TCDD on prostate cancer cells (PC-3) and non-tumor p
Objective. To examine psychiatric patients' experience of mechanical restraints and to describe the care the patients received. Background. All around the world, threats and violence perpetrated by patients in psychiatric emergency inpatient units are quite common and are a prevalent factor concerning the application of mechanical restraints, although psychiatric patients' experiences of mechanica
Cyclic nucleotide phosphodiesterases (PDEs) are important regulators of signal transduction processes mediated by cAMP and cGMP. One PDE family member, PDE3B, plays an important role in the regulation of a variety of metabolic processes such as lipolysis and insulin secretion. In this study, the cellular localization and the role of PDE3B in the regulation of triglyceride, cholesterol and glucose
The paper deals with the Cauchy problem for the linear constant-coefficient strongly hyperbolic system $u_t+Au_x=({1}/{delta})B$. The critical case where $B$ has a nontrivial nullspace is investigated. Under suitable assumptions on the matrices $A$ and $B$ the convergence in $L_2$ as $delta o 0$ of the solution $u(·,t,delta)$ of the Cauchy problem is proved. Then the evolution of the limit funct
Air quality standards are set to protect public health. The values of the standards are often based on health effect studies, without any statistical considerations. In order to judge if a standard is met measurements of ambient air quality are taken at monitoring stations, and these measured values are used to decide whether or not the standard has been violated. In this paper we examine the stat
Popular Abstract in Swedish De flesta av Sveriges cirka 15000 större broar är byggda i betong. Ett problem som kan uppkomma i betongbroar är sprickor, vilka kan bidra till att minska broarnas beständighet och säkerhet. I en del broar har fler sprickor uppkommit på sydsidan än på nordsidan vilket antyder att solen har stor påverkan på dessa broar, eftersom det är den enda faktor som skiljer sig väsWhen the temperature changes in the environment the temperature will also change in a structure. Complex interactions of climate factors affect the temperature changes. When the temperature is varied in a material it will expand or contract, and movements will be produced. If the movements are prevented, stresses may be induced which can contribute to cracks in the structure. Severe cracks have be
Inpatient withdrawal treatment (detoxification) is common in opioid dependence, although dropout against medical advice often limits its outcome. This study aimed to assess baseline predictors of dropout from inpatient opioid detoxification with buprenorphine, including age, gender, current substance use, and type of postdetoxification planning. A retrospective hospital chart review was carried ou
Using delayed-coincidence techniques we have measured the natural radiative lifetimes of several S and D states in Rb and Cs. The states were excited by a pulsed dye laser from the first P state, populated using an rf discharge lamp.
Between knowledge and nonsense – the mysterious churches of Bornholm: A critical discussion of two books by Erling Haagensen, where he postulate a sacred geometry on Bornholm and a treasure hidden by the Templars in the round church of Österlars – or somewhere else.
Abstract in UndeterminedComplex stimuli and tasks elicit particular eye movement sequences. Previous research has focused on comparing between these scanpaths, particularly in memory and imagery research where it has been proposed that observers reproduce their eye movements when recognizing or imagining a stimulus. However, it is not clear whether scanpath similarity is related to memory performa
Risk of human papillomavirus (HPV) transmission during laser vaporisation of genital warts or loop electrode excision procedure is controversial. An oral rinse, a nasal swabs, history of HPV-related diseases and data on HPV exposure were collected from 287 employees at departments of dermato-venerology and gynaecology in Denmark. A mucosal HPV type was found among 5.8% of employees with experience
BACKGROUND: The importance of voltage-dependent conductances in sensory information processing is well-established in insect photoreceptors. Here we present the characterization of electrical properties in photoreceptors of the cockroach (Periplaneta americana), a nocturnal insect with a visual system adapted for dim light. RESULTS: Whole-cell patch-clamped photoreceptors had high capacitances and
