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PURPOSE: Radionuclide imaging of insulin-like growth factor type 1 receptor (IGF-1R) expression in tumours might be used for selection of patients who would benefit from IGF-1R-targeted therapy. We have previously shown the feasibility of IGF-1R imaging using the Affibody molecule (111)In-DOTA-His(6)-Z(IGF1R:4551). The use of (99m)Tc instead of (111)In should improve sensitivity and resolution of

Affibody molecules are a class of affinity proteins. Their small size (7 kDa) in combination with the high (subnanomolar) affinity for a number of cancer-associated molecular targets makes them suitable for molecular imaging. Earlier studies demonstrated that the selection of radionuclide and chelator may substantially influence the tumor-targeting properties of affibody molecules. Moreover, the p

Chemicals is the industrial sector with the highest energy demand, using a substantial share of global fossil energy and emitting increasing amounts of greenhouse gasses following rapid growth over the past 25 years. Emissions associated with energy use have increased with growth in coal-dependent regions but are also commonly underestimated in regions with higher shares of renewable energy. Renew

In 2016, the Norwegian government initiated an extensive reform of the regional scale, eventually reducing the number of political-administrative counties from nineteen to eleven through mergers. The territorial and institutional changes that followed can be understood as a partial regional (de/re)institutionalisation process, in which the political and administrative boundaries of the merged coun

Abstract på spanskaUna de las fuentes más sólidas de nuevo conocimiento sobre las categorías tipológicas proviene de nuestro creciente entendimiento de las lenguas indígenas de América del Sur, una región que hasta hace poco ha estado significativamente subrepresentada en los estudios tipológicos. Este artículo ofrece un ejemplo a través de la investigación del número en nadëb, un miembro de la peOne of the most robust sources of fresh insights into typological categories comes from our growing knowledge of the indigenous languages of South America, a region that until recently has been significantly under-represented in typological studies. This paper offers a case in point through the investigation of number in Nadëb, a member of the small Naduhup family of the northwest Amazon, which re

Nominal classification is a robust feature in many Amazonian languages, and aspects of these systems offer significant challenges to our broader conception of the phenomenon. Yet a clear characterization of Amazonian classification systems must be firmly grounded in detailed descriptive analysis on one hand, and in a principled definition of classification as a typological category on the other –

Not all spatial adjuncts behave alike. In some languages, certain spatial adjuncts display different marking or different combinatorial possibilities than others. Recent functional-typological studies make two claims about this differential place marking phenomenon: (1) it is primarily motivated by noun semantics, opposing place names and other nouns; and (2) it is primarily realized as a contrast

Levinson (2003) provides evidence that distinct cultures display distinct spatial references that, as a consequence, impacts the linguistic encoding of spatial notions. This linguistic variation has fostered the interest of understanding the spatial domains responsible for the linguistic encoding of spatial information. According to Levinson and Wilkins (2006, p. 2), these domains consist in: the

Abstract in Portuguese:Referências a paisagens e lugares são elementos centrais nas narrativas tradicionais de falantes da língua Dâw (Naduhup,Amazônia brasileira). Essa ênfase na referência espacial é estabelecida principalmente por meio de orações adverbiaislocativas que são frequentemente repetidas ao longo do discurso. Sua função é relacionar um evento a um lugar, estabelecerreferência à inforReferences to landscape and places are central in traditional narratives by speakers of Dâw (Naduhup, Brazilian Amazon). This emphasis on spatial reference is primarily established through locative adverbial clauses that are often repeated throughout the discourse. Their function is to relate an event to a place, establish reference to locative information mentioned earlier in discourse, and provi

Non-β-hemolytic streptococci (NBHS) cause infective endocarditis (IE) and a short blood culture time to positivity (TTP) is associated with risk of IE in bacteremia with other pathogens. In this retrospective population-based cohort study, we investigate if TTP is associated to IE or mortality. Of 263 episodes with NBHS bacteremia, 28 represented IE and the median TTP did not differ significantly

SyfteMålsättningen med denna studie var dels att säkerställa att tågpersonalen inte utsätts för höga halter av partiklar i sitt arbete på X60B fordon som trafikerar Arlanda. Syftet var även att ta fram ett förhållande mellan partikelnivåerna i tunnelmiljö och ombord på pendeltågsfordon av typ X60B i förarhytterna för att avgöra ventilationsfiltrets kapacitet. Kunskapen om filtreringseffektiviteten

PM10 from the wear of disc brakes could contribute up to 50 % of the total non-exhaust emissions from road transport in EU. The wear originates from the contact surfaces of the friction material and the disc. One possible way of decreasing the PM10 emissions is to change the materials of the contact pair in terms of composition and coatings. Therefore the particle emissions of three novel friction

Recycling of brake pads is a tough but promising work considering the current end of lifecycle. This study assesses the environmental performance of brake pads made up of recycled friction materials in terms of energy use, CO2 footprint and airborne particle number. Energy use and CO2 footprint are calculated with the data from CES Edupack and airborne emission particle number is measured on a pin

Om vi vill rädda hotade insekts­arter är det miljöer med traditionella ängs­växter som vi behöver mer av, inte frö­blandningar av oklart ursprung från handeln. Det skriver flera debattörer.

We have combined high-energy surface X-ray diffraction (HESXRD) with 2D surface optical reflectance (2D-SOR) to perform in situ electrochemical measurements of a Au(111) electrode in 0.1 M HClO4 electrolyte. We show that electrochemically induced changes to Au(111) surface during cyclic voltammetry can be simultaneously observed with 2D-SOR and HESXRD. We discuss how small one atom high 1x1 island

Background: In many high-income countries, life expectancy (LE) has increased, with women outliving men. This gender gap in LE (GGLE) has been explained with biological factors, healthy behaviours, health status, and sociodemographic characteristics, but little attention has been paid to the role of public health policies that include/affect these factors. This study aimed to assess the contributi