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AbstractImmune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by low platelet counts. First-line treatment includes intravenous immunoglobulin (IVIg), however, its working mechanism remains incompletely understood. We investigated splenic and thymic dendritic cell (DC) subsets upon IVIg treatment in a well-characterized active murine model of ITP. During active disease, th

Denna promemoria bygger på resultat från en kvalitativ studie av folkbibliotek i fem skånska kommuner som 2018 publicerats i rapporten Styrdokumenten i vardagen: en undersökning av kulturpolitiska styrdokuments strategiska och praktiska betydelse för folkbibliotek i fem skånska kommuner. Studien genomfördes under 2016 och 2017 av Johanna Rivano Eckerdal och Hanna Carlsson. Fokus för studien var de

Many ships today rely on Global Navigation Satellite System (GNSS), for their navigation, where GPS (Global Positioning System) is the most well known. Unfortunately, the GNSS systems make the ships dependent on external systems, which can be malfunctioning, be jammed or be spoofed. There are today some proposed techniques where, e.g. bottom depth measurements are compared with known maps using Ba

In magnetomotive ultrasound (MMUS), solenoids have been extensively used to generate varying magnetic fields, that act to move nanoparticles and their surrounding tissue. Here we show, compare and contrast two magnetic devices, one based on a solenoid, another containing a rotating permanent magnet. Suitable field characteristics for this application include high flux density and gradient, and uni

An unmanned ship can be designed without considering humancomfort, and can thus be constructed lighter, smaller and less expensive.It can carry out missions in rough terrain or be in areaswhere it would be dangerous for a human to operate. By not havingto support a crew, lengthy missions can be accepted, enabling, e.g.reconnaissance missions, or reducing emissions by lowering thespeed.Breakthrough

The standard Godunov type method used in computational fluid dynamics shows accuracy problems for low Mach number flows and for the kinetic energy at the highest wave numbers resolvable on a given grid. Both drawbacks become visible when simulating the decay of isotropic turbulence at the low Mach numbers typical for the respective experimental investigations. A modification to cure both problems

We considered nonlinear solvers inside implicit time integration schemes for the time dependent compressible Navier-Stokes equations. The existing solvers turn out to be adequate, but amenable to significant improvements. Regarding multigrid schemes, we demonstrated that reoptimizing a multigrid scheme for the case of a time dependent equation leads to significant improvements in convergence speed

We consider thermal fluid structure interaction to model industrial gas quenching in steel forging, where hot steel Is cooled using cold high pressured gas. This allows to define properties of the finished steel part, as for example yield strength, locally at low cost and without environmental problems. For the numerical simulation, a partitioned approach via a Dirichlet-Neumann coupling and a fix

We consider the coupling of the compressible Navier-Stokes equations with the heat equation as a model for cooling processes in steel forming. The semidiscrete coupled system is solved using stiffly stable SDIRK methods of higher order, where on each stage, a fluid-structure interaction problem is solved. textcopyright 2009 American Institute of Physics.

This paper presents a scalable and high-Throughput hybrid computing platform for the real-Time multi-particle based Linac (Linear accelerator) simulation model to be used at the European Spallation Source (ESS). The multi-particle simulation model with non-linear modeling is needed to provide a realistic behavior of the particle beam for reducing the losses at the superconducting structures. The c

This paper presents a cryptographic processor compliant with the security algorithms specified by the 3rd Generation Partnership Project (3GPP) specifications for Long Term Evolution (LTE). The proposed processor has been adapted to the needs of the low end portfolio technologies that compose the Internet of Things (IoT) market, which addresses low-Area, low-cost and low-data rate applications. Th

Type 1 (T1D) and type 2 (T2D) diabetes are triggered by a combination of environmental and/or genetic factors. Maf transcription factors regulate pancreatic beta (β)-cell function, and have also been implicated in the regulation of immunomodulatory cytokines like interferon-β (IFNβ1). In this study, we assessed MAFA and MAFB co-expression with pro-inflammatory cytokine signaling genes in RNA-seq d

The production of Z bosons in association with a high-energy photon (Zγ production) is studied in the neutrino decay channel of the Z boson using pp collisions at s√=13 TeV. The analysis uses a data sample with an integrated luminosity of 36.1fb−1 collected by the ATLAS detector at the LHC in 2015 and 2016. Candidate Zγ events with invisible decays of the Z boson are selected by requiring signific