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Background: There is variation in the care provided to men with metastatic prostate cancer (mPCa). There has been no previous set of quality indicators (QIs) regarding the management of men with mPCa. The objective of this study is to develop a set of international mPCa-specific QIs, which will enable global benchmarking of quality of care. Materials and methods: Potential QIs were identified thro
Objective: Long-term automatic detection of focal seizures remains one of the major challenges in epilepsy due to the unacceptably high number of false alarms from state-of-the-art methods. Our aim was to investigate to what extent a new patient-specific approach based on similarly occurring morphological electroencephalographic (EEG) signal patterns could be used to distinguish seizures from nons
Importance: The US Food and Drug Administration (FDA) authorized SARS-CoV-2 rapid at-home self-test kits for individuals with and without symptoms. How appropriately users interpret and act on the results of at-home COVID-19 self-tests is unknown. Objective: To assess how users of at-home COVID-19 self-test kits interpret and act on results when given instructions authorized by the FDA, instructio
The aim of these guidelines is to provide evidence‑based guidance for temperature control in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying cardiac rhythm. These guidelines replace the recommendations on temperature management after cardiac arrest included in the 2021 post-resuscitation care guidelines co-issued b
Purpose: This paper explores the quality and flow of facade product information and the capabilities for avoiding the risk of facade fires early in the design process. Design/methodology/approach: A qualitative case study using the process tracing method is conducted in two stages. First, a thematic analysis of reports and literature identified two categories for the problems that caused fast fire
Background: The pathological response to preoperative chemotherapy of colorectal liver metastases (CRLMs) is predictive of long-term prognosis after liver resection. Accurate preoperative assessment of chemotherapy response could enable treatment optimization. Purpose: To investigate whether changes in lesion-apparent diffusion coefficient (ADC) measured with diffusion-weighted magnetic resonance
Background: The base of tongue squamous cell carcinoma (BOTSCC) is mainly an HPV-related tumor. Radiotherapy (EBRT) ± concomitant chemotherapy (CT) is the backbone of the curatively intended treatment, with brachytherapy (BT) boost as an option. With four different treatment strategies in Sweden, a retrospective study based on the population-based Swedish Head and Neck Cancer Register (SweHNCR) wa
Basis pursuit (BP), basis pursuit deNoising (BPDN), and least absolute shrinkage and selection operator (LASSO) are popular methods for identifying important predictors in the high-dimensional linear regression model (Formula presented.). By definition, when (Formula presented.), BP uniquely recovers (Formula presented.) when (Formula presented.) and (Formula presented.) implies (Formula presented
In optic neuritis (ON), transient thickening of the macular retinal nerve fibre layer (RNFL) can be observed. This optical coherence tomography-based observation is not understood. The axonal diameter correlates with the neurofilament (Nf) protein content, but there are no data on the retinal tissue concentration of Nfs. The myelin-oligodendrocyte-glycoprotein (MOG) induced experimental autoimmune
This article aims to understand the prevalent leadership models in seven prominent leadership development programmes targeting emerging and aspiring civil society leaders in Sweden and the United Kingdom (UK), which have two different civil society regimes. An analytical framework based on ideal-typical leadership models (transactional, transformational and collaborative) helps us distil how progr
Background: The impact of obesity on patient-reported outcome (PRO) after total knee arthroplasty (TKA) surgery has demonstrated varying results. We evaluated knee pain, Activity in Daily Life function (ADL), and satisfaction after TKA surgery in patients with and without prior bariatric surgery (BS). Methods: Scandinavian Obesity Surgery Registry (SOReg) and the Swedish Knee Arthroplasty Register
Various studies have claimed that the sense of agency is based on a comparison between an internal estimate of an action’s outcome and sensory feedback. With respect to speech, this presumes that speakers have a stable prearticulatory representation of their own speech. However, recent research suggests that the sense of agency is flexible and thus in some contexts we may feel like we produced spe
Hematopoietic stem cells (HSC) give rise to all types of blood lineages, including red blood cells (RBC). Hematopoietic stem/progenitor cells (HSPC) are known to be functionally diverse in terms of their self-renewal potential and lineage output. Consequently, investigation of molecular heterogeneity in the differentiation potential of HSPC is vital to identify novel regulators that affect generat
This chapter contains an overview of general policies regarding student housing in Sweden, a desription of market conditions for students renting a room or an apartment, and the legal framework regulating student housing in Sweden, including the rental contract.
BACKGROUND/AIM: Inflammation is a hallmark of cancer, and the role of neutrophils and neutrophil extracellular traps (NETs) in cancer and cancer-associated thrombosis has attracted a lot of interest. The NET-specific marker H3Cit has been found to be elevated in the plasma of patients with malignancies, suggesting NETs markers as novel cancer biomarkers. This study aimed to determine the levels of
Sb-based semiconductors are critical p-channel materials for III-V complementary metal oxide semiconductor (CMOS) technology, while the performance of Sb-based metal-oxide-semiconductor field-effect transistors (MOSFETs) is typically inhibited by the low quality of the channel to gate dielectric interface, which leads to poor gate modulation. In this study, we achieve improved electrostatics of ve
BACKGROUND AND PURPOSE: In total knee arthroplasty (TKA), metal-backed (MBT) and all-polyethylene (APT) designs have shown comparable implant migration up to 2 years postoperatively using radiostereometric analysis (RSA). However, studies comparing mid-term migration of both designs are lacking. Furthermore, continuously migrating TKAs up to 2 years may continue to migrate or stabilize thereafter
Virtual Reality has long been proposed to combine the reliability of controlled laboratory settings with the ecological validity of real life. While the technological development steadily pushes towards even more realistic renderings of the real world— the elusiveness of social and emotional elements gradually becomes more evident. This is not the least true for behavioral studies in rich sociocul
While the current research mainly deals with the Palestinian youth in the Middle East, reports from various organisations, whose most accounts are descriptive, hardly provide a sustained and critical evaluation of their nature and impact. With an urgent need to understand better youth engagement in exile under adverse conditions in a conflict-ridden society such as the Palestinian one, this paper
