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Currently, little is known about the spatial distribution of white matter hyperintensities (WMH) in the brain of patients with Systemic Lupus erythematosus (SLE). Previous lesion markers, such as number and volume, ignore the strategic location of WMH. The goal of this work was to develop a fully-automated method to identify predominant patterns of WMH across WM tracts based on cluster analysis. A
Det övergripande syftet med denna avhandling är att främja den konceptuella förståelsen av transformativ innovationspolitik genom empirisk forskning med fokus på omställningen till en cirkulär ekonomi i den danska avfallssektorn. Under detta breda syfte handlar avhandlingen mer specifikt om att utforska frågor relaterade till geografi i transformativ innovationspolitik samt såkallad övergångsdynamThe overall aim of this thesis is to advance the conceptual understanding of transformative innovation policy through empirical research focusing on the transition towards a circular economy in the Danish waste sector. Under this broad aim, the thesis is more specifically concerned with exploring issues relating to the geography of transformative innovation policy as well as transition dynamics an
Global megacities are rapidly transforming through slum redevelopment and alternative resettlements of evicted poor. Resettlement is broadly seen as enabling, a basis of improved housing and even a pathway towards urban citizenship. This article offers an alternative perspective on urban resettlement, whereby the urban poor are subjected to life-threatening housing interventions. It builds on Mbem
Background: Evidence is increasing for the use of faecal immunochemical tests (FITs) for occult blood as diagnostic tools when colorectal cancer can be suspected. FITs have been used for this purpose in Swedish primary care since around 2005 despite absence of supporting guidelines. To our knowledge, the extent of this use has not been studied. Objective: To investigate the use of FITs as diagnost
The labor market is strongly gender segregated with few women working in the tech sector (e.g. IT) and few men working in the care sector (e.g. nursing). We tested the hypothesis that middle school students strongly associate technology with men and caregiving with women, and that this relates to girls’ lower interest in tech-focused educations. We measured technology/caregiving gender stereotypes
För att se om antalet D-interaktioner kunde minskas skickades information om interaktioner på individnivå till vårdcentraler.Allmänläkarna ombads att utifrån medföljande rekommendationer ompröva behandlingen och besvara en enkät.Mindre än hälften av D-interaktionerna berodde på medvetna ordinationsval.Mer än hälften av interaktionerna hade uppkommit det senaste året, trots tydlig varning vid ordinDuring 2012, one Swedish national goal for better health for elderly was to decrease drug-drug interactions. We performed an intervention, where the physicians in primary health care were alerted to which of their patients had a drug-drug interaction. The physicians received a letter with patient information and recommendations on how to act. They were requested to review if the interactions still
Background: A consistent imaging biomarker to standardize the evaluation of change in bone scan is an unmet need for patients (pts) with bone metastasis. BSI is quantitative interpretation of bone scan in pts with metastatic prostate cancer (mPCa). Here we have performed analytical and clinical studies to evaluate the change in computer automated BSI as a consistent imaging biomarker in pts with m
Background: Enzalutamide (ENZ), an androgen receptor antagonist therapy, was approved for patients (pts) with mCRPC. However, in standard of care for mCRPC pts, change in prostate specific antigen (PSA) is not accepted as an efficacy response measurement and the radiological change is inadequately measured in an interpreter-dependent subjective analysis of bone scan. Therefore, an objective effica
This report on detailed aerosol characterization of fire smoke emissions is part of the Fire-Induced Radiological Integrated Assessment (FIRIA; CERN, Switzerland). In this study, carried out at Lund University, a number of materials were combusted in a cone calorimeter at varied heat fluxes. In a few experiments, the effect of reduced O2 content of supply air was investigated (vitiated conditions)
Purpose/Objective(s): To report the efficacy and utility of PSMA-based molecular targeted imaging in localized prostate cancer using 111In-J591 SPECT and 89Zr-J591 immuno-PET.Materials/Methods: Initiated in 2010, two sequential phase 0 prospective studies were performed on a total of 19 patients evaluating the roles of 111In-J591 SPECT and 89Zr-J591 immuno-PET. All patients had a baseline MRI foll
Introduction and Objectives: To compare pilot cohorts of men scheduled for radical prostatectomy imaged with novel antibody conjugates: Cohort 1 (111In-J591) single photon emission tomography (SPECT) or Cohort 2 (89Zr-J591) positron emission tomorgraphy (PET).Methods: 1) Cohort 1: Eight patients with abnormal digital rectal exam and biopsy proven prostate cancer were injected intravenously with tw
Andfåddhet är en subjektiv upplevelse och utgör ett ospecifikt, vanligt och potentiellt allvarligt symtom som tidigt bör utredas strukturerat tills orsaken är klarlagd, med fokus på att utesluta allvarliga differentialdiagnoser.Ökad medvetenhet om allvarlighetsgraden av andfåddhet kan minska fördröjning till diagnos samt förbättra prognosen, inte minst vid sällsynta sjukdomar såsom PAH (pulmonell Dyspnea is a common distressing symptom which may be a sign of a critically threatening condition and has been linked with increased hospitalizations, reduced exercise tolerance and increased mortality. The current neuropsychological model suggests that dyspnea arises due to an imbalance between respiratory drive and achieved ventilation. Pulmonary arterial hypertension (PAH) and chronic thromboem
This study aimed to conduct a systematic literature review (SLR) of the research performed in the plant-based meat analogues area. Historical, current, and future tendencies are discussed. The paper offers a comprehensive SLR coupled with a bibliometric analysis of the publication from 1972 to January 2022. The articles were obtained using a research string and precise inclusion and exclusion crit
The parents’ attitude toward vaccinating children and adolescents against coronavirus disease 2019 (COVID-19) remains inconsistent and needs further elucidation. The high rates of COVID-19 vaccine hesitancy in the Middle East and North Africa (MENA) region require intensive research to understand the determinants of this phenomenon. This study aimed to validate a version of the Parent Attitudes ab
Cervical cancer is one of the most recurrent and dangerous female cancers in Algeria and worldwide. It is mainly caused by human papillomaviruses (HPV), which can induce other cancers as well. Although it can be fatal, cervical cancer is one of the most preventable and manageable cancers. While HPV vaccination is the key weapon to win the battle against this pathology, it is still not approved in
We consider a nonlinear vertex-reinforced jump process (VRJP(w)) on Z with an increasing measurable weight function w : [1, ∞) → [1, ∞) and initial weights equal to one. Our main goal is to study the asymptotic behaviour of VRJP(w) depending on the integrability of the reciprocal of w. In particular, we prove that if (Equation presented). then the process is recurrent, that is, it visits each vert
In this work, we perform a detailed study of transition form factors for axial- vector meson production via the two-photon fusion process γ*γ* → 1++, with space-like virtual photons in the initial state and a P-wave axial-vector quarkonium in the final state. In this analysis, we employ the formalism of light-front quarkonium wave functions obtained from a solution of the Schrödinger equation for
(1) Background: Villous atrophy is an indication for small bowel capsule endoscopy (SBCE). However, SBCE findings are not described uniformly and atrophic features are sometimes not recognized; (2) Methods: The Delphi technique was employed to reach agreement among a panel of SBCE experts. The nomenclature and definitions of SBCE lesions suggesting the presence of atrophy were decided in a core gr
An expert panel convened by the European Alliance for Personalized Medicine (EAPM) reflected on achievements and outstanding challenges in Europe in mantle cell lymphoma (MCL). Through the prism of member state experience, the panel noted advances in outcomes over the last decade, but highlighted issues constituting barriers to better care. The list notably included availability of newer treatment
