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The revitalization of existing neighborhoods has been a frequent topic of public and academic debate in post–industrial times. Yet, little is known about the potential of individual, commercial real estate development projects to revitalize neighborhoods. Adaptive reuse of existing buildings, especially when combined with collaborative spaces, have been linked to positive social impacts beyond cul
PurposeThis study aims to determine whether employees are satisfied with their connection to colleagues when working from home (WFH), whether their satisfaction is influenced by sociodemographic factors and home-based work settings and whether cross-country differences exist.Design/methodology/approachUsing survey data from 137,487 knowledge workers across 88 countries, collected during a real-wor
Marine ecosystems are consisted with variety of life, accounting for over 80% of the Earth's biodiversity. This rich biodiversity in marine environment includes more than 30,000 species of fish. Additionally, marine biological resources are reservoirs of numerous bioactive compounds with various physiological functions such as antioxidant, anti-inflammatory, anticancer, antiaging, antibacterial, a
In this chapter I trace a series of central and well-connected urban squares in Malmö and Lund, Sweden from the 1960s until today. It investigates how the squares have developed in relation to the practice of shopping and other activities during these decades and concludes with the discussion of a few more recent trends. Starting with the deterioration of the open urban markets, followed by the in
The role of the architect seems to be constantly renegotiated, due to social change, and technological development. In spite of the proliferation of architectural research, however, architectural knowledge may still be grounded in design experience and cultural values transmitted during the early years of an architect’s training. Furthermore, most scholarly studies on architectural practice and ed
Intraventricular hemorrhage (IVH) in preterm infants disrupts neurogenesis in the subventricular zone (SVZ), a key neurogenic niche, yet no effective treatments exist. This work develops a human SVZ-on-a-chip model to investigate the inflammatory response in IVH and its impact on neurogenesis. Using this platform, this work examines the effects of red blood cell lysate (RBCL) and hemorrhagic cereb
Objective To compare neurodevelopmental outcomes in extremely preterm (EPT) children born across two epochs in Sweden. Design and setting Nationwide population-based cohorts of infants born at 22–26 weeks’ gestation in 2004–2007 (Cohort 1) and 2014–2016 (Cohort 2), comprising 1606 live births. Survivors were assessed at 2–2.5 years’ corrected age using the same protocol design. Main outcome The pr
Eight compounds were isolated from the water-soluble fraction of Wikstroemia indica (L.) C.A. Mey., including two new neolignans (isonitidanin-4-O-β-D-glucoside (3) and threo-citrusin B (6)), four known neolignans (1, 2, 4, and 5), along with two previously reported lignans (7 and 8). Spectral analysis (1D, 2D NMR, and HR-ESI-MS/MS) was used to identify their chemical structures. Except for compou
Road traffic pollution is one of the most important factors among other environmental factors that influence the roadside vegetation. The present research examines the impact of motorway flyovers and at-grade roads on air pollution (PM10, SOx, NOx, and air quality index (AQI)) and roadside vegetation in Dehradun by considering the important biochemical parameters such as chlorophyll, ascorbic acid
Avoiding exceeding planetary boundaries, while still achieving a decent standard of living for all is a global challenge represented in the so-called doughnut model. Policies for local mobility in line with the doughnut model, will lead to less and slower mobility for many people. This paper contributes to doughnut literature with insights regarding people’s visions of life with doughnut-inspired
The “Warburg effect”, a metabolic adaptation observed in dividing cells, involves a shift from mitochondrial oxidative phosphorylation to cytoplasmic glucose metabolism. This metabolic process is characterized by increased cellular uptake of glucose and glutamine, elevated intracellular pH and sodium levels, enhanced protection against oxidative stress, altered autophagy, and increased lactate pro
Background and aim: The MY PD-CARE digital tool is intended to empower people with Parkinson’s disease (PD) and care partners to actively identify and track changes in key symptoms of advancing PD and to facilitate discussions with healthcare professionals (HCPs). MY PD-CARE was adapted from MANAGE-PD, a validated, web-based tool that helps HCPs identify patients with inadequate symptom control. T
We present the time-resolved luminescence end station developed at the FemtoMAX beamline at the MAX IV Laboratory for the studies of ultrafast energy relaxation and emission properties. The instrument consists of a temperature-controlled vacuum chamber sample environment, in which the UV–visible luminescence is collected from the point of interaction of ultrashort x-ray pulses with luminescent mat
Human hands can perform far more gestures than the number of muscles controlling them, as most gestures result from coordinated combinations of muscle activations and relaxations. This complexity poses a key challenge for human-machine interfaces performing gesture classification based on electromyography (EMG). Rather than identifying all conceivable gestures, it may be simpler to instead identif
Digitalization of the downstream process for monoclonal antibodies can be used as a tool towards more efficient and sustainable processing. One part of digitalization are digital twins, which can help provide insights into a process and be used for process optimization, reducing production costs and accelerating drug discovery. However, creating a useful digital twin is often difficult and time-co
Spermine, a pivotal player in biomolecular condensation and diverse cellular processes, has emerged as a focus of investigation in aging, neurodegeneration, and other diseases. Despite its significance, the mechanistic details of spermine remain incompletely understood. Here, we describe the distinct modulation by spermine on Alzheimer’s Tau and Parkinson’s α-synuclein, elucidating their condensat
A piece that deals with: A. Where does the real Ecumenical debate stand today - between the confessions or rather between conservative and liberal streams of the church? B: What is the relationship between Ecumenical conversation and inter-religious conversation?
Background: Self-rated health (SRH) is an international measure and indicator of mortality and morbidity that can be used as a mortality predictor in adulthood. This study aimed to examine the status of SRH among adults in Qazvin Province and its relationship with physical activity levels and demographic factors in primary care centers. Methods: This is a cross-sectional study. We included data fr
