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Polycrystalline cubic boron nitride (pcBN) is a very promising tool material for turning martensitic stainless steels at high cutting speeds (vc > 200 m/min). The competitive advantage of pcBN over cemented carbide increases as the cutting speed is increased. Changing the speed might lead to a shift in the wear balance and hence the knowledge about tool wear below vc = 200 m/min might not be appli

The Adverse Outcome Pathways (AOPs) framework is pivotal in toxicology, but the, terminology describing Key Event Relationships (KERs) varies within AOP guidelines.This study examined the usage of causal, observational and predictive terms in AOP, documentation and their adaptation in AOP development. A literature search and text, analysis of key AOP guidance documents revealed nuanced usage of th

Dopaminergic (DA) neurons exhibit significant diversity characterized by differences in morphology, anatomical location, axonal projection pattern, and selective vulnerability to disease. More recently, scRNAseq has been used to map DA neuron diversity at the level of gene expression. These studies have revealed a higher than expected molecular diversity in both mouse and human DA neurons. However

Stem cell therapies for Parkinson's disease are at an exciting time of development, and several clinical trials have recently been initiated. Human pluripotent stem cells are differentiated into transplantable dopamine (DA) progenitors which are proliferative at the time of grafting and undergo terminal differentiation and maturation in vivo. While the progenitors are homogeneous at the time of tr

This thesis concerns control of capacity-constrained networks. These systems involve many agents interconnected by a resource distribution network. The capacity to generate and distribute this resource is constrained. This applies, for instance, to power grids, communication networks, smart surveillance camera networks, and district heating networks. District heating networks in particular are the

Climate change is causing an intensification of soil drying and rewetting events, altering microbial functioning and potentially destabilizing soil organic carbon. After rewetting, changes in microbial community carbon use efficiency (CUE), investment in life history strategies, and fungal to bacterial dominance co-occur. Still, we have yet to generalize what drives these dynamic responses. Here,

Performance designed around a harbour tour in the Copenhagen harbour. The concept, idea and staging was done by Erik Pold and Adelaide Bentzon, the artistic directors of Public Performance. 5 performers where the main characters in the boat or along the harbour, together with 20 extras, and live electronic music. The performance takes a critical view on how the contemporary harbour area has develo

Introduction:Knowledge about long-time residual symptoms, disabilities, and psychological health in complex regional pain syndrome (CRPS) is limited.Objectives:The aim was to evaluate outcome, focusing on physical symptoms, disability, and psychological health, in individuals with CRPS through a cross-sectional survey study.Methods:Individuals with a confirmed diagnosis of CRPS were identified thr

Monoclinic β-Ga2O3 films grown on c-plane sapphire have been shown to exhibit six (2¯01)-oriented domains, which are equally spaced by rotation around the surface normal and equally sized by volume that render the film optical response effectively uniaxial. We derive and discuss an optical model suitable for ellipsometry data analysis of such films. We model mid- and far-infrared ellipsometry data

Hemslöjdspionjären Lilli Zickerman (1858–1949), som tog initiativ till bildandet av Föreningen för svensk hemslöjd, var under nära fyra decennier bosatt i Vittsjö. Det var därifrån som hon tillsammans med flera familjemedlemmar, som också flyttat dit, arbetade med en stor inventering av svensk folklig textilkonst. Inventeringsmaterialet, som bär namnet ”Föreningen för svensk hemslöjds samlingsverk

The accumulation of amyloid fibrils from the protein 𝛼-synuclein is a pathological hallmark of Parkinson´s disease. 𝛼-synuclein is a highly polar protein with a remarkable primary structure that can be divided into three regions: the slightly basic N-terminal region, a central hydrophobic region, and a highly acidic C-terminal tail. The C-terminal tail is of specific focus in this thesis. A chan