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The growing vulnerability of cities to extreme heat underscores the urgency of effective urban adaptation policies. Despite the progress in developing urban climate policies and strategies, there remains a significant disparity between intended goals and actual outcomes. This could entrench social and climate vulnerabilities that are costly and challenging to address, potentially resulting in rein
We report the discovery of two warm exoplanets orbiting the cool binary system TOI-2267, composed of the M5 (TOI-2267A) and M6 (TOI-2267B) stars, whose angular separation is 0.384 arcsec, corresponding to a projected distance of only about 8 au at 22 pc from the Solar System. To confirm the planetary nature of these objects, we combined photometry from the Transiting Exoplanet Survey Satellite (TE
Through digital imaging, microscopy has evolved from primarily being a means for visual observation of life at the micro- and nano-scale, to a quantitative tool with ever-increasing resolution and throughput. Artificial intelligence, deep neural networks, and machine learning (ML) are all niche terms describing computational methods that have gained a pivotal role in microscopy-based research over
In this chapter, the author synthesises insights from across the book to demonstrate how myths about sustainable consumption persist and hinder systemic change. The chapter identifies five mechanisms that explain their persistence: cultural reinforcement, anchoring in daily practices, institutional embedding, psychological appeal and political function. These mechanisms reveal why myths remain inf
Mood, an individual’s emotional state, fundamentally shapes how the brain interprets sensory input by providing a continuous affective context for prediction and evaluation. In language processing, mood may bias the interpretation of emotionally valenced words, amplifying or dampening their perceived affect. Yet, the temporal dynamics of these mood-valence interactions remain poorly understood. To
Mood is a pervasive affective state that influences cognition, including language processing, where it functions as part of the pragmatic context. When linguistic expressions carry emotional valence, mood may amplify or attenuate their perceived emotional nature. Motivated by inconsistent findings on the timing and nature of mood and valence interactions, we conducted an EEG study to investigate w
Background: Asthma with low levels of type 2 (T2) biomarkers is poorly understood. Objective: To characterize severe asthma phenotypes and compare changes in asthma outcomes from pre- to postbiologic treatment along a gradient of T2 involvement. Methods: This was a registry-based cohort study including data from 24 countries. Biomarker distribution (blood eosinophil count, fractional exhaled nitri
Allergy, characterised by antibody responses of the IgE isotype, is a major health concern. The set of monoclonal human IgE used for studying the molecular mechanisms of allergies is limited. Single-cell sequencing offers opportunities to establish novel antibodies for researching, diagnosis, and treatment of allergies. We describe and exploit a pipeline for generating recombinant IgE directly fro
The Perseverance rover landed in Jezero crater on Mars, which once contained a lake of liquid water. We report the rock properties encountered by Perseverance during a 10-kilometer traverse extending over 400 meters in elevation, from beneath Jezero's western sedimentary fan to the upper crater rim. These rocks consist of coarse-grained olivine, magnesium and iron carbonates, silica, and phyllosil
Age of Information (AoI) is a widely used metric to quantify the freshness of updates in communication systems. Existing AoI analyses implicitly assume a shared or synchronized notion of time between transmitter and receiver, thereby neglecting distortions arising from relative motion and gravitational effects. In this paper, we investigate the impact of relativistic time dilation on information f
Objective: In the present study, we investigated the role of the gut–liver crosstalk in the pathogenesis of steatotic liver disease (SLD) induced by the compounding and deleterious effects of alcohol and metabolic risk factors, and explored the potential translational aspects of microbiome-based interventions. Design: The effects of combined exposure to alcohol and a high-fat, high-cholesterol die
The link between regional tau load and clinical manifestation of Alzheimer's disease (AD) highlights the importance of characterizing spatial tau distribution across disease variants. In typical (memory-predominant) AD, the spatial progression of tau pathology mirrors the functional connections from temporal lobe epicentres. However, given the limited spatial heterogeneity of tau in typical AD, at
Objective To compare longitudinal speech outcomes at ages 5 and 10 years in foreign-born and Swedish-born children with cleft palate with or without cleft lip (CP ± L), and assess impact of cleft type, additional diagnosed conditions, sex, and age at completed primary palatal surgery.DesignLongitudinal, registry-based cohort study.SettingRegional public care university hospitals in Sweden.Particip
