Filetype
Understanding uncertainties and sensitivities of projected ecosystem dynamics under environmental change is of immense value for research and climate change policy. Here, we analyze sensitivities (change in model outputs per unit change in inputs) and uncertainties (changes in model outputs scaled to uncertainty in inputs) of vegetation dynamics under climate change, projected by a state-of-the-ar
Aquaporins (AQPs) are a family of transmembrane water channels expressed in all living organisms. AQPs facilitate osmotically driven water flux across biological membranes and, in some cases, the movement of small molecules (such as glycerol, urea, CO2, NH3, H2O2). Protein–protein interactions play essential roles in protein regulation and function. This review provides a comprehensive overview of
There has been a public debate among academics and politicians of whether Hungary should be required to join the European Public Prosecutor’s Office as a condition to receive EU funds according to the different milestones. As the EPPO is tasked with investigating fraud and mismanagement of EU funds, it is well-placed to address the allegations of serious corruption that the Hungarian Government is
PURPOSE: Evaluate patient-reported knee function after arthroscopic partial meniscectomy (APM) and meniscus suture repair in two different age cohorts compared with a normal population.METHOD: Arthroscopic meniscus surgery was performed on 421 patients at Skåne University Hospital from 2010 to 2014, with a mean (SD) follow-up of 4.2 (1.4) years. Patients and controls were divided into two age coho
The impacts of adverse weather conditions on railway systems can lead to large delays and cancellationsacross the entire network. In this paper, we aim to understand the relationship between weather andtrain disruptions (i.e. cancellations and large delays) across the entire Swedish railway network for theyears 2011-2019. Using railway operations data and snow depth, temperature, precipitation, an
Background Chromium (Cr) contact allergy is frequent in many industrialized countries. The knowledge of the factors that can influence percutaneous penetration is very important assessing the risk of human exposure. Objective The aim of the study was to compare the concentration of Cr in various skin layers using 2 different vehicles. Methods Full-thickness (approximately 1 mm) porcine ear skin wa
High-quality simulated data is crucial for particle physics discoveries. Therefore, parton shower algorithms are a major building block of the data synthesis in event generator programs. However, the core algorithms used to generate parton showers have barely changed since the 1980s. With quantum computers’ rapid and continuous development, dedicated algorithms are required to exploit the potentia
ATP7B is a human copper-transporting P1B-type ATPase that is involved in copper homeostasis and resistance to platinum drugs in cancer cells. ATP7B consists of a copper-transporting core and a regulatory N-terminal tail that contains six metal-binding domains (MBD1-6) connected by linker regions. The MBDs can bind copper, which changes the dynamics of the regulatory domain and activates the protei
Akvifären Alnarpsdalen är 6 - 10 km bred och sträcker sig från Skivarp i sydost till Löddeköpinge i nordväst och vidare ut i Öresund. Trots att flertalet kommuner i Skåne numera försörjs med vatten från Vombsjön eller Bolmen finns det kommuner, industrier och jordbrukare som använder vatten från Alnarpsdalen.Det finns ett antal frågor som kan ställas gällande Alnarpsdalen, till exempel hur mycket
Background: There is growing attention and policy debate about the sharing of personal information that the modernization of electricity grids requires. This is particularly important for big data management in smart grids that needs access to data generated and sent through devices such as smart meters. Using the Nordic Countries as a case study, this study investigates the willingness of people
Tensions between migration enforcement and migrants’ health and rights have gained renewed urgency during the COVID-19 pandemic. This article critically analyses how the pandemic has affected detained and deportable people in Sweden. Building on an activist methodological approach and collaboration, based on a survey conducted inside Swedish detention centres during the pandemic and the authors’ r
The multi-electrode electrical resistivity method has become one of the most efficient geophysical methods used in a wide range of applications, which is also suitable when disturbances in the ground are to be avoided. The selection of the right electrode configuration can provide better effectiveness, depending on the target being investigated. In this work a case of the use of three electrode arThe multi-electrode electrical resistivity method has become one of the most efficient geophysical methods used in a wide range of applications, which is also suitable when disturbances in the ground are to be avoided. The selection of the right electrode configuration can provide better effectiveness, depending on the target being investigated. In this work a case of the use of three electrode ar
Background Indications with poor T-cell infiltration or deficiencies in T-cell priming and associated unresponsiveness to established immunotherapies represent an unmet medical need in oncology. CD40-targeting therapies designed to enhance antigen presentation, generate new tumor-specific T cells, and activate tumor-infiltrating myeloid cells to remodel the tumor microenvironment, represent a prom
Background: An understudied variant of Alzheimer's disease (AD), the behavioral/dysexecutive variant of AD (bvAD), is associated with progressive personality, behavior, and/or executive dysfunction and frontal atrophy. Objective: This study characterizes the neuropsychological and neuroanatomical features associated with bvAD by comparing it to behavioral variant frontotemporal dementia (bvFTD), a
Increasing tree growth and mortality rates in Europe are still poorly understood and have been attributed to a variety of drivers. This study explored the role of climate drivers, management and age structure in driving changes in tree mortality rates in six Central European countries from 1985 to 2010, using the process-based vegetation model LPJ-GUESS. Simulations show a strong positive trend in
A substantial portion of molecules in an organism are involved in regulation of a wide spectrum of biological processes. Several models have been presented for various forms of biological regulation, including gene expression regulation and physiological regulation; however, a generic model is missing. Recently a new unifying theory in biology, poikilosis, was presented. Poikilosis indicates that
Denmark is currently undertaking extensive groundwater mapping surveys in designated water interest areas. The mapping objectives include vulnerability assessments, delineation of existing aquifers, and localization of new deeper lying aquifers. Airborne electromagnetics are employed for regional mapping to depths of hundreds of meters. Resistivity profiling and pulled-array geo-electrics are utilDenmark is currently undertaking extensive groundwater mapping surveys in designated water interest areas. The mapping objectives include vulnerability assessments, delineation of existing aquifers, and localization of new deeper lying aquifers. Airborne electromagnetics are employed for regional mapping to depths of hundreds of meters. Resistivity profiling and pulled-array geo-electrics are util
Knee pain is an early sign of knee osteoarthritis (KOA) and a risk factor for chronic widespread pain (CWP). Early prevention is vital, and more research is needed to understand health-promoting activities for individuals with knee pain from a patient perspective. This study aimed to explore how individuals with knee pain experienced health-promoting activities. Explorative qualitative design with
