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In recent years, nonhuman ancient DNA studies have begun to focus on larger sample sizes and whole genomes, offering the potential to reveal exciting and hitherto unknown answers to ongoing biological and archaeological questions. However, one major limitation to such studies is the substantial financial and time investments still required during sample screening, due to uncertainty regarding succ
Objectives: This study determined: 1) the interobserver agreement; 2) valvular flow variation; and 3) which variables independently predicted the variation of valvular flow quantification from 4-dimensional (4D) flow cardiac magnetic resonance (CMR) with automated retrospective valve tracking at multiple sites. Background: Automated retrospective valve tracking in 4D flow CMR allows consistent ass
PURPOSE Antiangiogenic therapy using bevacizumab has proven effective for a number of cancers; however, in breast cancer (BC), there is an unmet need to identify patients who benefit from such treatment. PATIENTS AND METHODS In the NeoAva phase II clinical trial, patients (N = 132) with large (= 25 mm) human epidermal growth factor receptor 2 (HER2)-negative primary tumors were randomly assigned 1
In this chapter, we argue that to understand the interdisciplinary and transdisciplinary dialectics in sustainability science, it is useful to see sustainability science as a kind of management science, and then to highlight the hard–soft distinction in systems thinking. First, we argue that the commonly made natural–social science dichotomy is relatively unimportant and unhelpful. We then outline
Resilience is a concept that is both foundational and, at the same time, relentlessly controversial in sustainability science. It is supposed to both provide a fundamental insight into how complex adaptive systems behave—an insight with substantial normative consequences—and serve as an interdisciplinary bridge linking the disparate worlds of the natural and the social sciences. Yet the concept of
Sustainability science is fundamentally an interdisciplinary venture, but what does this interdisciplinarity imply in practice? And how can, and should, we think about interdisciplinarity more generally? These are important philosophical and methodological questions for sustainability science, the answers to which remain at least partially out of sight for a variety of reasons. This chapter has th
In the seventeenth Century, Swedish aristocratic women successfully acted as managers of landed estates, mills and iron works, and exerted agency in politics. Making qualified decisions and overseeing complex enterprises, their actions in many ways contradicted the prevailing patriarchal ideology. While explanations for this agency have stressed several intersecting factors, the role of learning a
School refusal (SR) can have several negative consequences, but effective treatments are available. When chronic, school absence requires comprehensive treatment. This study evaluates an intervention for SR based on a Cognitive Behavioral Therapy (CBT) model, Hemmasittarprogrammet (HSP). Attendance, anxiety, depression, quality of life, and emotional and behavioral symptoms were measured at pre-tr
This paper presents a structured optimization framework for reducing the computational complexity of LDPC decoders. Subject to specified performance constraints and adaptive to environment conditions, the proposed framework leverages the adjustable performance-complexity tradeoffs of the decoder to deliver satisfying performance with minimum computational complexity. More specifically, two constra
Weber's notion of value spheres is famous but underdeveloped as a theory framework. Prominent sociologists have shown that it can be used as a unifying force in functionalist differentiation theory, and as a tool in the analysis of modernity. One of the theorists in this tradition is Hans L. Zetterberg, who throughout his varied career remained attached to the idea of society as composed of six va
Översiktlig analys av hur tidningen Lundagård under 100 år tecknat sin historia genom särskilda jubileumsutgåvor vart femte år sedan 1925.
Background: Visual exploration of gene product behavior across multiple omic datasets can pinpoint technical limitations in data and reveal biological trends. Still, such exploration is challenging as there is a need for visualizations that are tailored for the purpose. Results: The OmicLoupe software was developed to facilitate visual data exploration and provides more than 15 interactive cross-d
Up to 10% of pediatric cancer patients harbor pathogenic germline variants in one or more cancer susceptibility genes. A recent study from the US reported pathogenic variants in 22 out of 60 analyzed autosomal dominant cancer susceptibility genes, implicating 8.5% of pediatric cancer patients. Here we aimed to assess the prevalence of germline pathogenic variants in these 22 genes in a population-
This paper presents a robust and low-complexity non-linearity suppression scheme for radio frequency (RF) transceiver building blocks to efficiently mitigate intermodulation distortion. The scheme consists of tunable RF components assisted by an auxiliary path equipped with an adaptive digital signal processing algorithm to provide the tuning control. This proposed concept of digitally-assisted tu
