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Background and purpose: Neuroblastoma is the most common extracranial solid tumour in children. Radiotherapy is commonly part of the multimodal treatment for high-risk patients. The aim of this study is to analyse doses to organs at risk (OAR) in comparative proton and photon treatment plans for children treated for neuroblastoma and report side effects. Patient/material and methods: All children
Background Labels for neck pain after a motor vehicle crash (MVC) influenced recovery expectations and management preferences. Research is needed to understand why these expectations and preferences varied based on the label given. Aim To explore how people perceive different labels for neck pain after an MVC. Methods We performed a content analysis of qualitative data from a randomised controlled
Climate warming, nutrient loading, and pesticide pollution are major anthropogenic stressors affecting community dynamics and trophic interactions in aquatic ecosystems. However, the complex interplay among these stressors remains poorly understood as most studies focus on a single stressor and overlook the effects of temporal variations. To address this knowledge gap, we first conducted a long-te
Indigenous archaeology and archaeology of Indigeneity are paramount in the contemporary world. We certainly need more of it across the archaeological scale and across the archaeological globe. Archaeology’s unhealthy attachment to colonialism, colonial administration and imperialism keeps on affecting our discipline on all levels. It is therefore encouraging to read Felix Acuto’s call for an engag
Gold mining is widespread in the Colombian Amazon and negatively impacts biodiversity, climate, and social equity. While some claim that sustainable gold mining can address these issues, we have analyzed different narratives of sustainable gold mining, focusing on equity and power dimensions. Our research, conducted through participatory observation and interviews across scales between 2022 and 20
Analyzing kinetic experiments on protein aggregation using integrated rate laws has led to numerous advances in our understanding of the fundamental chemical mechanisms behind amyloidogenic disorders such as Alzheimer's and Parkinson's diseases. However, the description of biologically relevant processes may require rate equations that are too complex to solve using existing methods, hindering mec
The twin transition, which combines green and digital innovation in economic activities, is increasingly central to policy agendas and is also receiving growing attention in regional research. However, accurately mapping green, digital and twin (both green and digital) economic activities across regions remains challenging, particularly due to data constraints. In this study, we advance this resea
Objective: Severe obesity poses a major public health concern due to its links with cardiometabolic complications and mortality. Visceral adipose tissue (VAT) plays a key role in these processes through distinct molecular features. This study aimed to characterize the VAT proteome of individuals with severe obesity and investigate its association with serum metabolic biomarkers. Methods: A cross-s
Background: Fine-needle aspiration biopsy (FNAB) of lymph nodes is a widely used method for evaluating lymphadenopathy. FNAB offers general advantages of rapid turnaround time, low cost and minimal morbidity, and more specific advantages in various clinical situations, such as deeply located lymph nodes or patients with significant comorbidities. The FNAB sample can be utilized for a wide range of
Background: Low lung function has been consistently associated with increased cardiovascular disease (CVD) risk, with emerging evidence suggesting a potential causal relationship. However, underlying biological mechanisms remain unclear. Aim: To investigate relationships between CVD-associated plasma proteins and lung function. Methods: We analysed plasma protein profiles in two Swedish population
The meeting between public life in the city and our private bodily needs creates sensitive and complex architectural challenges, and public toilets are a clear example. They are often seen as merely practical and technical spaces, but they also reveal how a city thinks about accessibility, safety, and equality. How can these places meet basic needs while still feeling safe, clean, and welcoming? A
In response to the environmental crisis and growing consumer awareness, increasing attention has been directed towards sustainable production models centred on circularity, resource efficiency, and reduced environmental impact. Against this background, practices such as upcycling, which aim to extend product lifespans and reduce waste, have gained increased attention. The European Union has artic
Den 1 juli 2025 infördes DNA-baserad släktforskning som ett polisiärt utredningsverktyg i Sverige. Metoden kallas även utredande genetisk genealogi och har hyllats som en ”kriminalteknisk revolution” och beskrivits i termer som ”genombrott”. Att inga uppklarade brott offentliggjorts och inga fällande domar meddelats sedan ikraftträdandet väcker däremot frågor om dess egentliga straffprocessuella bOn July 1, 2025, genetic genealogy was introduced as a tool for police investigations in Sweden. The method is also called investigative genetic genealogy and has been praised as a “forensic revolution” and described in terms such as “breakthrough”. However, the fact that no solved crimes have been made public and no convictions have been issued since its commencement raises questions regarding it
Denna uppsats undersöker huruvida nuvarande kontrollåtgärder gällande efterlevnaden av kollektivavtal är tillräckligt effektiva, samt hur eventuella ytterligare kontrollåtgärder skulle påverka den bristande efterlevnaden av kollektivavtal samt den svenska modellen. Syftet med uppsatsen är att undersöka möjligheter och begränsningar knutna till befintliga och föreslagna kontrollåtgärder gällande eThis thesis examines whether current control measures regarding compliance with collective agreements are sufficiently effective, and how any additional control measures would affect the lack of compliance with collective agree ments and the Swedish model. The purpose of the thesis is to examine the possibilities and limitations associated with existing and proposed control measures regarding comp
The continued reliance on cars presents a challenge for sustainable mobility policy. A wide range of approaches exists to address this issue, from promoting more sustainable vehicle options to replacing cars altogether. However, national sustainable mobility policies related to car use often suffer from spatial blindness–which implies a limited contextual differentiation based on the specific char
Chemical vapour deposition enables large-domain growth of ideal graphene, yet many applications of graphene require the controlled inclusion of specific defects. We present a one-step chemical vapour deposition procedure aimed at retaining the precursor topology when incorporated into the grown carbonaceous film. When azupyrene, the molecular analogue of the Stone-Wales defect in graphene, is used
IMPORTANCE COVID-19 can lead to long-term cardiopulmonary symptoms and is associated with coronary microvascular dysfunction (CMD). However, long-term data on CMD after severe COVID-19 are lacking. OBJECTIVE To investigate long-term left ventricular function and the presence of CMD after severe COVID-19. DESIGN, SETTING, AND PARTICIPANTS This case-control study was conducted among patients at a si
Background Although the role of smoking as a risk factor for emphysema in α1-antitrypsin deficiency (AATD) is well known, never-smokers with severe AATD may also develop lung disease, ranging from mild asymptomatic disease to severe emphysema. Methods We performed a cross-sectional and observational study to analyse the characteristics of the population of never-smoker severe AATD (genotype) indiv
Background: Despite recommendations by EU, surveillance of Lyme neuroborreliosis (LNB) is still not fully implemented in all member states, Sweden being one of them. Laboratory-based notifications on positive Borrelia antibody index (AI) in paired cerebrospinal fluid-serum samples alone have been suggested for surveillance of LNB. Objectives: We aim to describe the epidemiology of Lyme borreliosis
