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New publication from Lund University New publication in BMC Psychiatry.Read more here.
National joint registries are gaining more and more importance in the fields of implant monitoring/outlier detection and quality of care. New publication in Bone & Joint.Read more here.
https://www.lupop.lu.se/article/orthopaedic-registries-german-experience - 2025-12-20
Most data on the epidemiology of cardiogenic shock (CS) have come from patients with acute myocardial infarction admitted to intensive cardiac care units (ICCUs). However, CS can have other aetiologies, and could be managed in intensive care units (ICUs), especially the most severe forms of CS. New publication in Archives of Cardiovascular Diseases.Read more here.
Hip fracture registries have helped improve quality of care and reduce variability, and several audits exist worldwide. The results of the Spanish National Hip Fracture Registry are presented and compared with 13 other national registries, highlighting similarities and differences to define areas of improvement, particularly surgical delay and early mobilization. New publication in Osteoporosis In
Clinical registries are health information systems, which have the mission to collect multidimensional real-world data over the long term, and to generate relevant information and actionable knowledge to address current serious healthcare problems. New publication in Bone & Joint.Read more here.
https://www.lupop.lu.se/article/registry-stakeholders - 2025-12-20
The Nordic Arthroplasty Register Association (NARA) was established in 2007 by arthroplasty register representatives from Sweden, Norway and Denmark with the overall aim to improve the quality of research and thereby enhance the possibility for quality improvement with arthroplasty surgery. Finland joined the NARA collaboration in 2010. New publication in Bone& Joint.Read more here.
https://www.lupop.lu.se/article/benefits-collaboration-nordic-arthroplasty-register-association - 2025-12-20
A major challenge in clinical research today is the difficulty that studies have in meeting recruitment goals. Up to 48% of studies do not meet accrual goals within the specified timeframe, significantly delaying the progress of projects and the dissemination of findings. This pervasive problem is a recruitment crisis. We developed a representative, ethnically and racially diverse research partici
https://www.lupop.lu.se/article/developing-and-launching-research-participant-registry - 2025-12-20
The National Spinal Cord Injury Registry of Iran (NSCIR-IR) is a not-for-profit, hospital-based, and prospective observational registry that appraises the quality of care, long-term outcomes and the personal and psychological burden of traumatic spinal cord injury in Iran. Benchmarking validity in every registry includes rigorous attention to data quality. New publication in Chinese Journal of Tra
Vascunet has previously published an international comparison of registry data within vascular surgery. Data validity and completeness in participating registries is essential for a meaningful interpretation of differences between countries. The Vascunet collaboration has therefore developed a methodology for validation of international vascular registry data, previously used for validation of two
https://www.lupop.lu.se/article/international-validation-danish-vascular-registry-karbase-vascunet-report - 2025-12-20
The use of clinical autopsy has been in decline for many years throughout healthcare systems of developed countries despite studies showing substantial discrepancies between autopsy results and pre-mortal clinical diagnoses. We conducted a study to evaluate over time the use and results of clinical autopsies in Sweden. We reviewed the autopsy reports and autopsy referrals of 2410 adult (age > 17)
https://www.lupop.lu.se/article/cause-death-and-significant-disease-found-autopsy - 2025-12-20
Inflammatory bowel disease (IBD) is a chronic, inflammatory relapsing disease with increasing incidence. IBD research and long-term follow-up of patients have, however, been hampered by lack of detailed data on disease phenotype, patient-reported outcome measures, Physician Global Assessment, disease activity, and hospital-administered drugs. New publication in Scandinavian Journal of Gastroentero
https://www.lupop.lu.se/article/swedish-inflammatory-bowel-disease-register-swibreg-nationwide-quality-register - 2025-12-20
The World Cancer Research Fund International has concluded strong evidence for that high intake of dairy products and foods containing dietary fiber and low intake of processed meat are associated with decreased risk of colorectal cancer (CRC). As food items are consumed together, it is important to study dietary patterns. New publication in European Journal of Cancer Prevention
Orphan drugs are medicines intended to treat, prevent, or diagnose a rare and serious condition. The collection of pre-marketing safety and efficacy data for orphan drugs is very challenging for several reasons related to the rarity of the diseases. This highlights the need for robust post-marketing evidence generation. Real-world data sources, such as claims databases, electronic healthcare recor
Patient registries are routinely used in dermatology and psoriasis registries offer pertinent long-term safety information regarding conventional systemic therapies and biologic agents for psoriasis. New publication in Journal of Dermatological Treatment
https://www.lupop.lu.se/article/review-european-registries-psoriasis - 2025-12-20
Oestrogen receptor-positive (ER+) and human epidermal receptor 2-negative (HER2–) breast cancers are classified as Luminal A or B based on gene expression, but immunohistochemical markers are used for surrogate subtyping. The aims of this study were to examine the agreement between molecular subtyping (MS) and surrogate subtyping and to identify subgroups consisting mainly of Luminal A or B tumour
Patient registries, ‘organised systems that use observational methods to collect uniform data on a population defined by a particular disease, condition, or exposure, and that is followed over time’, are potentially valuable sources of data for supporting regulatory decision-making, especially for products to treat rare diseases. Nevertheless, patient registries are greatly underused in regulatory
https://www.lupop.lu.se/article/patient-registries-underused-resource-medicines-evaluation - 2025-12-20
To assess the impact on exposure time and outcome misclassifications, and consequent impact on exposure-outcome associations from treatment episode construction. We investigated the dosage assumptions of 1 unit per day, and 1 DDD per day, versus actual prescribed dosage under different handling of gaps and overlaps of prescriptions. New publication in European Journal of Clinical Pharmacology
https://www.lupop.lu.se/article/methods-constructing-treatment-episodes-and-impact-exposure-outcome-associations - 2025-12-20
The aim of this study was to examine whether the self‐reported use of analgesics is associated with being a victim of bullying. New publication in Acta Paediatrica
https://www.lupop.lu.se/article/bullying-pain-and-analgesic-use-school-age-children - 2025-12-20
Sibling comparison designs have long been used to assess causal effects of exposures for which randomized studies are impossible and measurement of all relevant confounding is unobtainable. The idea is to utilize the fact that siblings often share a lot of unobserved variables. Therefore, it is proposed that in certain cases, comparing siblings is equivalent to comparing exchangeable individuals,
https://www.lupop.lu.se/article/what-causal-interpretation-sibling-comparison-designs - 2025-12-20
A central element of assimilation theory is that increasing time and number of previous immigrant generations in a host country leaves immigrants and their children more integrated and capable of navigating the host society. However, the underperformance of some immigrant groups in Sweden calls into question this relationship. Additionally, many studies regard intermarriage as an outcome of immigr
