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Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

06032016 679 07 richesson jms 2010

ORIGINAL PAPER Achieving Standardized Medication Data in Clinical Research Studies: Two Approaches and Applications for Implementing RxNorm Rachel L. Richesson & Susan B. Smith & Jamie Malloy & Jeffrey P. Krischer Received: 16 December 2008 /Accepted: 15 March 2009 /Published online: 3 April 2009 # Springer Science + Business Media, LLC 2009 Abstract The National Institutes of Health has proposed

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_07_richesson_jms_2010.pdf - 2026-05-23

Evolutionary and functional studies of protein H: a surface molecule of Streptococcus pyogenes

Popular Abstract in Swedish Protein H - ett bakteriellt ytprotein med förmåga att binda till olika proteiner hos människa Bakgrund I vårt dagliga liv omges vi av bakterier av många olika slag. Flertalet av dessa är normalt ofarliga och många utgör den så kallade normalfloran hos människa. En del bakterier kan under vissa förhållanden ge upphov till infektion och sjukdom, men för att åstadkomma d

Anna Lundberg

Head of department Contact details Email: anna [dot] lundberg [at] soclaw [dot] lu [dot] se Mobile: +46 70 946 62 30Organisation Sociology of Law Department Service point: 31 WebpageAnna Lundbergs profile in Lund University research portalOther affiliations Professor Sociology of Law Department Profile area member LU Profile Area: Human rights Publications Displaying of publications. Sorted by yea

https://www.humanrights.lu.se/anna-lundberg - 2026-05-22

MartinaA Caretta CV 210308

Curriculum vitae MARTINA ANGELA CARETTA, PHD Birth date : 29th April 1986 Citizenships : Sweden and Italy martina_angela.caretta@keg.lu.se PROFESSIONAL EXPERIENCE January 2021- Senior Lecturer Human Geography Department, Lund University, Sweden August 2016 – December 2020 Assistant Professor of Geography Dept. of Geology and Geography, West Virginia University, USA December 2016 – November 2017 UN

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/2021-03/MartinaA_Caretta_CV_210308.pdf - 2026-05-23

MartinaA Caretta CV 210726

Curriculum vitae MARTINA ANGELA CARETTA, PHD Birth date : 29th April 1986 Citizenships : Sweden and Italy martina_angela.caretta@keg.lu.se PROFESSIONAL EXPERIENCE January 2021- Senior Lecturer Human Geography Department, Lund University, Sweden August 2016 – December 2020 Assistant Professor of Geography Dept. of Geology and Geography, West Virginia University, USA December 2016 – November 2017 UN

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/2021-08/MartinaA_Caretta_CV_210726.pdf - 2026-05-23

Produktkatalog2

Produkt- och tjänstekatalog LU SERVICE | MEDIA-TRYCK | LUNDS UNIVERSITET 2018 PRODUKT & TJÄNSTEKATALOG 2018 Med reservation för prisändringar och eventuella tryckfel Copyright Media-Tryck Typsnitt Adobe Garamond Pro och Frutiger Papper i inlagan Scandia smooth white 130 gr Omslagspapper Scandia smooth white 300 gr Tryck Media-Tryck, Lund 2018 Efterbehandling Media-Tryck Webb www.mediatryck.lu.se L

https://www.mediatryck.lu.se/en/sites/mediatryck.lu.se.en/files/2023-05/produktkatalog2.pdf - 2026-05-23

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Språk- och litteraturcentrum Franska Litteraturlista FRAA12, franska, fortsättningskurs, 30 högskolepoäng Fastställd av Styrelsen för Sektion 3 2025-12-11 att gälla från VT25 Referenslitteratur för samtliga delkurser Wall, Kerstin; Béhar, Dennis; Ekman, Monika & Kronning, Hans (2014). Den franska grammatiken. Stockholm: Sanoma utbildning, ISBN 9789152327166 (336 sidor). NEs stora franska ordbok (s

https://www.sol.lu.se/media/utbildning/dokument/kurser/FRAA12/20261/FRAA12_2.pdf - 2026-05-21

An R package of maximum entropy production model to estimate 41 years of global evapotranspiration

An accurate estimation of evapotranspiration (ET) is vital for understanding the global hydrological cycle. However, large uncertainties in the present global ET products originate from the distinct model structures, assumptions, and inputs. The maximum entropy production (MEP) model provides a novel method for modeling ET based on parsimonious inputs and energy conservation. In this study, an R p

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The aim of this article is to show that at the end of the 13th century there’s a change of approach to the sophistical syllogism, going from a definition based on its formal features to a definition based on its pragmatic features. The first position is put forward by Simon of Faversham, during the 1280s, probably during his stay in Paris. The second position is put forward by Radulphus Brito, the