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Aims In anticoagulation treatment with warfarin, the risk of thrombo-embolic events must be weighed against the risk of bleeding. Time in therapeutic range (TTR) is an important tool to assess the quality of anticoagulation treatment, and has been shown to correlate with less bleeding and thrombo-embolic complications. AuriculA, the Swedish national quality registry for atrial fibrillation and ant

Energy expenditure, energy intake, body composition and selected biochemical analyses were studied in 14 males and 16 females with a mean age of 83 years (range 68-92) in geriatric long-stay wards. Energy expenditure was predicted from heart rate monitoring, and energy intake was assessed with a 4-day dietary record. Lean body mass (LBM), body fat (BF), and total body water (TBW) were estimated wi

Technical standards often implicate patented technologies. This poses a risk of patent hold-up, whereby a standard essential patent (“SEP”) holder opportunistically exploits its market power conferred by standardization and demands excessive and possibly differential royalties from implementers of the standard. Commitments to license on fair, reasonable, and non- discriminatory (“F/RAND”) terms im

Toxin-producing Staphylococcus aureus can be present in raw milk and therefore in cheese made from raw milk. To determine the number and type of toxin producers in raw milk used for raw milk cheese production in Ireland, 117 samples of raw milk and related products from five raw milk suppliers, to four raw milk cheesemakers in the South of Ireland, were analysed for coagulase positive S. aureus. E

Textile industry is one of the most polluting industries in the world and fast fashion is the unsustainable practice that most consumers are following. Adopting the habit of purchasing secondhand goods can lead to a more sustainable life. However, some people still do not prefer to consume secondhand clothes because of various stigma and barriers attached to it. In order to eliminate the stigma an

Miljoner människor faller årligen offer för människohandel världen över och efterfrågan på framförallt kvinnor och barns sexuella tjänster är stor. Sverige har en unik lagstiftning mot köp av sexuella tjänster med nära koppling till och avskräckande effekt på människohandelsindustrin. För att möjliggöra mer nyanserade bedömningar, exempelvis i fall där den som erbjuder tjänsten är offer för männisEach year millions of people are victim of human trafficking and the demand for women’s and children's sexual services is particularly high. Sweden has a unique law criminalizing the purchase of sexual services, which is closely linked to the human trafficking industry. On July 1st, the maximum penalty for the purchase of sexual services will be raised to imprisonment for one year. This will a

"My memories from Algiers - Between power and trust in Algiers' diplomatic spaces during Henric Gottfrid Brandel's accession to the consular office 1765-1768." In 1764, Henric Gottfrid Brandel was appointed consular secretary to the Swedish consul in Algiers. He would remain as secretary until late 1765 and early 1766, when he was appointed as temporary consul by the then current

The Canadian Arctic currently faces changing coastlines due isostatic rebound and climate change-driven sea-levels rising. This thesis seeks to answer how local coastlines will change over time under different Representative Concentration Pathway (RCP) scenarios, where errors in modelled coastlines come from, and how much of an impact isostatic rebound has on sea-levels compared to climate-change

The aim of this Master´s thesis is to explore how public libraries in a successful way can work in projects with young people. It intends to point out different factors that in a legible way affect the accomplishment and outcome of the project. Another purpose of the study is to uncover the various approaches existing within the projects towards young people and to find out why it is seen as impor

Smoked ham is commonly eaten in Sweden. However, smoked ham consists of a lot of salt (NaCl) which is an important component in the brine. Since a high salt consumption increases the risk of cardiovascular diseases, it is of great interest to decrease salt and other sodium-binding compounds in various food products, especially in smoked ham. Nevertheless, this is a challenge because the salt and o

Background: Swirl sign has previously been described in epidural hematomas as areas of low attenuation, radiolucency or irregular density. The aims of this study were to describe swirl sign in ICH, study its prevalence, study the reliability of the subjective evaluation on computed tomography (CT), and to explore its prognostic value. Methods: CTs of 203 patients with ICH were retrospectively eval

High-grade serous ovarian carcinoma (HGSOC) is the most common subtype of ovarian cancer, often discovered in advanced stages and linked to poor survival. Due to high mortality rates, there is a need for novel treatment strategies. A promising new strategy is induction of ferroptosis, which has recently been shown to synergistically induce cell death in HGSOCs in combination with MTDH-SND1 protein

Ovarian cancer is the most lethal gynecological malignancy, with treatment heavily relying on platinum-based chemotherapy. However, resistance frequently develops, posing a major clinical challenge that underscores the need for new approaches. In this study, we investigated the phosphoproteomic landscape underlying cisplatin resistance, which remains poorly understood. A parental CAOV3 ovarian can

Purpose: Choline is an essential nutrient for fetal and infant growth and development. Parenteral nutrition used in neonatal care lack free choline but contain small amounts of lipid-bound choline in the form of phosphatidylcholine (PC). Here, we examined the longitudinal development of serum free choline and metabolically related compounds betaine and methionine in extremely preterm infants and h

Background: In the laparoscopic Roux-en-Y gastric bypass procedure, the gastrojejunal stoma is constructed with either a circular (CSD) or a linear stapling device (LSD). The diameter of the stoma following stapling with the 21 mm CSD is expected to be approximately 12 mm (diameter of the anvil). Measuring the stoma diameter after linear stapling is a little more complex since the remaining openin