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Background Lactobacillus reuteri converts glycerol to 3-hydroxypropionic acid (3HP) and 1,3-propanediol (1,3PDO) via 3-hydroxypropionaldehyde (3HPA) as an intermediate using enzymes encoded in its propanediol-utilization (pdu) operon. Since 3HP, 1,3PDO and 3HPA are important building blocks for the bio-based chemical industry, L. reuteri can be an attractive candidate for their production. However
FKBP12 serves a dual role as a peptidyl-prolyl cis-trans isomerase and as a modulator of several cell signaling pathways. The macrolide FK506 is a transition-state analog of the catalyzed reaction and displaces FKBP12 from its natural target proteins. We compared the conformational exchange dynamics of the backbone and methyl-bearing side chains of FKBP12 in the free and FK506-bound states using N
OBJECTIVES: This is the first nationwide study with the aim to analyze whether there is an association between country of birth in first-generation immigrants and hospitalization for type 2 diabetes (T2D), and to study whether any such association remains in second-generation immigrants. DESIGN: In this follow-up study, the Swedish Hospital Discharge Register was used to identify all hospital
The term gastrointestinal neuromuscular disease describes a clinically heterogeneous group of disorders of children and adults in which symptoms are presumed or proven to arise as a result of neuromuscular, including interstitial cell of Cajal, dysfunction. Such disorders commonly have impaired motor activity, i.e. slowed or obstructed transit with radiological evidence of transient or persistent
In this work the synthesis of waterborne polyurethane/nanosilica nanocomposites by using two differ-ent strategies is presented, starting from a vinyl terminated polyurethane prepolymer (PUP) based onisophorone diisocyanate and polypropylene glycol, and varying the nanosilica content. In one case, thePUP was dispersed in an aqueous solution containing glycerol-functionalized colloidal nanosilica p
Background: Mass screening for celiac disease (CD) as a public health intervention is controversial. Prior to implementation, acceptability to the targeted population should be addressed. We aimed at exploring adolescents' and parents' experiences of having the adolescents' CD detected through mass screening, and their attitudes towards possible future mass screening. Methods: All adolescents (n =
Offentligrättsliga sanktioner av EU:s konkurrensrätt är ett välutvecklat område. Detsamma gäller dock inte för civilrättsliga sanktioner. Kommissionen har antagit en Grönbok, som beskriver flera problem som behöver lösas för att uppnå att privata sanktioner i framtiden fungerar som ett naturligt komplement till de offentligrättsliga. Skadeståndsanspråk framförs i nationell domstol i en medlemsstat
Phenological vegetation characteristics are valuable inputs to several ecosystem-related models: including carbon exchange and climate change. Phenological characteristics are effective measures of changes in vegetation in an area and are subject to the seasonal and inter-annual climatic variations. In arid and semi-arid ecosystems, precipitation is the main driving factor for changes in vegetatio
Striving to contribute to research on child- and youth spirituality and African theology with a contextually grounded, non-western, qualitative youth perspective, the aim of this study is to seek an understanding of the spirituality of male youth that live on the streets in Nairobi. To fulfil this aim, the research task carried out is an analysis of the source material from six focus group intervi
The so-called capitalist crisis of care has been theorized starting since the 80s. It has been and explored by two literature streams: the ‘feminist’ and the ‘mainstream’. New social and economic challenges in relation to welfare state systems trigger the interest of scholars and policy makers who are looking for sustainable responses to care needs. Welfare states have been repeatedly grouped into
Insects have been recommended by the FAO as a sustainable food alternative to meat. Despite their nutritional quality and sustainability, most Western countries still see insects as belonging far away from the dinner table. Although still a niche market, Denmark has been at the forefront of innovation and adoption of edible insects. I used integral theory to map out the structural, cultural and pe
Here a lung-on-a-chip device was developed and fabricated using 3D-printing of molds. The lung-on-a-chip device was used as a lung injury model by overstretching of murine lung epithelial cells (MLE-12) monolayers, resembling the injury during mechanical ventilation. The cells were exposed to 25% strain, representing pathological conditions seen in ventilator induced lung injury of patients with
How does anti-tourism affect support for the EU? This question has gained a newly found relevance in recent years, as anti-tourism protests have appeared in many European cities with high levels of tourism. Despite this relevance, some elements of these protests have not received as much attention as they deserve. This thesis will aim to fill one of the gaps in the literature: how anti-tourism soc
Studiens syfte är att få förståelse för hur vitt nikotin-snus påverkar unga tjejers sociala liv genom att förstå vilken statussymbol snuset har fått i ungdomskulturen. Detta var av intresse på grund av den stora ökade användning av vitt nikotin-snus bland unga tjejer, mellan åldrarna 16-29, i Sverige de senaste åren. För att förstå detta valde författarna att jämföra insamlad empiri, vilken samlad
The rise of China and 1978-market reforms contrasts other post-socialist economies process of institutional and economic change. President Deng Xiaoping announced China’s continued commitment to socialism, yet his leadership is by some viewed to be the most radical social and economic transformation in contemporary Chinese history. One of the most extraordinary aspects of the Chinese reform period
The occurrence of climate change will have a significant impact on society and adapting to a more sustainable environment is of key importance. The dangers of climate change will include temperature and precipitation patterns becoming more extreme creating a substantial impact on society. Greece’s location and climate make it particularly vulnerable to a changing climate and climate impact assessm
Popular summary The environmental and social consequences of predicted climate change are expected to be amplified in urban environments due to their elevated temperatures, which are attributable to a phenomenon known as the Urban Heat Island. As most types of vegetation can provide for cooler air temperatures due to their natural cooling effect, increasing amounts of vegetation in urban areas mig
Large quantities and numbers of organic compounds (OCs) from industries and domestic sources enter the wastewater treatment plants (WWTPs) everyday, which is an ever-increasing issue in modern society. In WWTPs, the pollutants are either degraded or emitted to the air, the effluent (water) or the sludge (biosolids). Even though the sludge may contain toxic contaminants and heavy metals, there is a
Restored salt marsh; topography, hydrology and vegetation Coastal salt marshes are shaped through a combination of physical (i.e., sediment accumulation/erosion) and biological (i.e., vegetation) processes. They are characterized by fine sediments and halophytic vegetation. The accretion rate and elevation change has been indicated as one of the most important factors in ecology of the marshes. T
