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BACKGROUND: Melanoma, the deadliest form of skin cancer, exhibits resistance to conventional therapies, particularly in advanced and metastatic stages. Mitochondrial pathways, including oxidative phosphorylation and mitochondrial translation, have emerged as critical drivers of melanoma progression and therapy resistance. This study investigates the mitochondrial proteome in melanoma to uncover no
Molnens roll i klimatsystemet har studerats och deras påverkan på solens inverkan på jordens energibalans. Jordens albedo påverkar energibalansen genom att den påverkar hur mycket av solens instrålning som reflekteras eller absorberas. Moln påverkar jordens albedo och spelar därför en viktig roll i denna balans. Molnbildning sker till nära 100% i troposfären och där finns allt det vi kallar väder.The role of clouds in the climate system has been studied and their impact on the Sun's impact on the Earth's energy balance. The Earth's albedo affects the energy balance by influencing how much of the Sun’s radiation is reflected or absorbed. Clouds affect the Earth's albedo and therefore play an important role in this balance. Cloud formation occurs almost 100% in the tropospher
This thesis investigates the impact of U.S. sanctions imposed between 2010 and 2012 on Iran’s non-oil exports. Using the Synthetic Control Method (SCM) as the baseline strategy, complemented by an Event Study and a standard Difference-in-Differences (DiD) model, the analysis shows that sanctions led to a sharp and persistent decline in Iran’s export performance relative to a counterfactual scenari
BACKGROUNDThe accuracy of estimation of kidney function with the use of routine metabolic tests, such as measurement of the serum creatinine level, has been controversial. The European Kidney Function Consortium (EKFC) developed a creatinine-based equation (EKFC eGFRcr) to estimate the glomerular filtration rate (GFR) with a rescaled serum creatinine level (i.e., the serum creatinine level is divi
AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and
With the development of new radiopharmaceutical therapies, quantitative SPECT/CT has progressively emerged as a crucial tool for dosimetry. One major obstacle of SPECT is its poor resolution, which results in blurring of the activity distribution. Especially for small objects, this so-called partial-volume effect limits the accuracy of activity quantification. Numerous methods for partial-volume c
The complex dynamics of protein expression in plasma during hyperacute HIV-1 infection and its relation to acute retroviral syndrome, viral control, and disease progression are largely unknown. Here, we quantify 1293 blood plasma proteins from 157 longitudinally linked plasma samples collected before, during, and after hyperacute HIV-1 infection of 54 participants from four sub-Saharan African cou
Two photoactive iron N-heterocyclic carbene complexes [FeII(btz)2(bpy)]2+ and [FeIII(btz)3]3+, where btz is 3,3’-dimethyl-1,1’-bis(p-tolyl)-4,4’-bis(1,2,3-triazol-5-ylidene) and bpy is 2,2’-bipyridine, have been investigated by Resonant Photoelectron Spectroscopy (RPES). Tuning the incident X-ray photon energy to match core-valence excitations provides a site specific probe of the electronic struc
Background: Previous population-based studies investigating the relationship between physical activity and the gut microbiota have relied on self-reported activity, prone to reporting bias. Here, we investigated the associations of accelerometer-based sedentary (SED), moderate-intensity (MPA), and vigorous-intensity (VPA) physical activity with the gut microbiota using cross-sectional data from th
Objectives Better understanding of societal factors associated with COVID-19 vaccination can have important implications for public health policy to increase uptake.Methods This study investigated sociodemographic determinants of COVID-19 vaccine uptake with ≥2 doses vs 0 doses, and ≥3 doses vs 2 doses, among adults (≥18 years) in a general population from Sweden followed from 27 December 2020 (n=
BACKGROUND: Melanoma is a highly heterogeneous disease, and a deeper molecular classification is essential for improving patient stratification and treatment approaches. Here, we describe the histopathology-driven proteogenomic landscape of 142 treatment-naïve metastatic melanoma samples to uncover molecular subtypes and clinically relevant biomarkers.METHODS: We performed an integrative proteogen
Objective To investigate the relationship between active commuting and atherosclerosis in middle age using state-of-the-art coronary CT angiography (CCTA). Methods This cross-sectional study used data from the Swedish CArdioPulmonary bioImage Study (SCAPIS) and included 23 722 randomly recruited individuals aged 50–64 years from six different regions in Sweden. The exposure was commuting mode, ass
The human influence on Earth's ecosystems is omnipresent. Artificial light at night (ALAN), anthropogenic noise, and air pollution are inherent features of human activities and infrastructure and pose novel environmental challenges to urban-dwelling wildlife. So far, most of the studies investigating the impacts of exposure to urban pollutants on animals have either investigated the effects of urb
Japan’s problem of vacant homes has drawn global media attention, but the situation may not be as dire as once predicted. While a 2015 report estimated a vacancy rate of 20.1 per cent by 2023, the actual figure was 13.8 per cent, thanks in part to policy reforms, awareness campaigns and grassroots efforts. Yet challenges remain amid an ageing population. Japan’s evolving approach offers valuable l
This study presents an example of when the government introduced a regulation that did not coincide research, professional ethics, responsibility or commitments, and led to a conflict between professionals and rulers.In the Swedish statutes regulating opioid maintenance treatment (OMT), a unique definition of the term opiate-dependency, the opiate rule, was introduced in 2010—restricting the targe
Microsoft Word - Self-evaluation SASNET 2.doc SASNET Self-evaluation 2000 - 2004 14 April 2005 Staffan Lindberg Lars Eklund Jan Magnusson SASNET – Swedish South Asian Studies Network Lund University Scheelevägen 15B (House Alfa 1) SE-223 70 Lund Sweden Phone: +46 46 222 73 49 Fax: +46 46 222 30 41 E-mail: sasnet@sasnet.lu.se Website: http://www.sasnet.lu.se 2 Executive summary A major aim of SASNE
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/self_evaluation_2005.pdf - 2026-06-26
200212. D€. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start. # Session Required readings Session focus Module 1: Setting the stage 1 Money today, theory and practice April 20, 13.00-16.00 Anders Ögren, Ester Barinaga, Paul Stankovski & Christian Gehrmann Readings: • Werner, R.2014. Can
https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200212._deu._schedule_syllabus.pdf - 2026-06-26
Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report https://doi.org/10.2337/dc18-2282 OBJECTIVE Assessment of the predictive power of TEDDY-identified risk factors for islet autoimmunity (IA), the type of autoantibody appearing first, and type 1 diabetes (T1D). RE
https://www.teddy.lu.se/sites/teddy.lu.se/files/105_mp221_krischer_diab_care_2019.pdf - 2026-06-26
Uppsatsmall MELLAN DELTAGANDE OCH INFLYTANDE En kartläggning av brukarråd i Skånes kommuner HÅKAN JOHANSSON, LINN JOHANSSON & ROBERTO SCARAMUZZINO MEDDELANDE FRÅN SOCIALHÖGSKOLAN, LUNDS UNIVERSITET, 2011:3 Mellan deltagande och inflytande: En kartläggning av brukarråd i Skånes kommuner Håkan Johansson, Linn Johansson & Roberto Scaramuzzino Meddelande från Socialhögskolan, Lunds universitet, 2011:3
https://www.soch.lu.se/sites/soch.lu.se/files/ms2011-3_0.pdf - 2026-06-26
