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Clofarabine has been shown to effectively induce remission in children with refractory leukemia. We conducted a prospective trial (clinicval.trials.gov NCT01025778) to explore the use of clofarabine-based chemotherapy as a bridge-to-transplant approach. Children with refractory acute leukemia were enrolled to receive two induction courses of clofarabine, etoposide, and cyclophosphamide (CloEC). Re
I den offentlege debatten om høgare utdanning er undervisarane påfallande fråverande. Dei sterkaste stemmene tilhøyrar politikarane, studentane, institusjonsleiarane og pedagogane. Når undervisarane melder seg på er det oftast i ein klagesong over høgt arbeidspress, krevjande studentar og mangel på tid og ressursar til forsking. Kvifor oppfattar brorparten av undervisarar i hI den offentlege debatten om høgare utdanning er undervisarane påfallande fråverande. Dei sterkaste stemmene tilhøyrar politikarane, studentane, institusjonsleiarane og pedagogane. Når undervisarane melder seg på er det oftast i ein klagesong over høgt arbeidspress, krevjande studentar og mangel på tid og ressursar til forsking. Kvifor oppfattar brorparten av undervisarar i h
Acute leukemia, myelodysplastic syndromes (MDS), myeloproliferative neoplasms and lymphomas are the most prevalent diagnoses in adults presenting with new onset cytopenia. Here, we describe two 10-color panels of surface markers (screening and comprehensive panel) applied at the Flow Cytometry Laboratory, University Health Network, Toronto, ON, Canada. A 10-color flow cytometry is applied using th
A search for a narrow scalar resonance decaying into an opposite-sign muon pair produced in events with and without b-tagged jets is presented in this paper. The search uses 36.1 fb−1 of s=13 TeV proton-proton collision data recorded by the ATLAS experiment at the LHC. No significant excess of events above the expected Standard Model background is observed in the investigated mass range of 0.2 to
Despite controversies, flu vaccine programs targeted to the older people are highly recommended and represent a common public health policy in industrialized Countries. Although demographic aging will increase the share of population at higher risk of influenza, today economic recession is putting public budgets under pressure. Underfunding of prevention is becoming a larger problem, as prevention
Sweden is a country that traditionally respects the freedom of association and the large number of existing trade unions confirms this statement.On the other hand, however, the Swedish trade union system is structured in a way that eliminates almost every sort of competition between different organizations. In fact, for every sector of the economy there is approximately one union for blue collars
Searches for new heavy resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons, are presented using a data sample corresponding to 36.1 fb-1 of pp collisions at s=13 TeV collected during 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting bosonic decay modes in the qqqq, ννqq, ℓνqq, ℓℓqq, ℓνℓν, ℓℓνν, ℓνℓℓ, ℓℓℓℓ,
Skolarbete på särskilda ungdomshem har seglat upp på dagordningen de senaste åren. Det är ingen överdrift att säga att skolans status har stärkts. I riktlinjer från 2014 anger Statens institutionsstyrelse att 'skola och utbildning ska vara i fokus'. Lärare och behandlingsassistenter ska bilda team kring den unge och arbeta tillsammans. Samtidigt är det heller ingen överdrift att säga att skolan ha
This Letter presents a search for new light resonances decaying to pairs of quarks and produced in association with a high-pT photon or jet. The dataset consists of proton–proton collisions with an integrated luminosity of 36.1 fb−1 at a centre-of-mass energy of s=13 TeV recorded by the ATLAS detector at the Large Hadron Collider. Resonance candidates are identified as massive large-radius jets wi
BACKGROUND: The role of sleeping problems in the causal pathway between job strain and musculoskeletal pain is not clear. Purpose: To investigate the impact of sleeping problems and job strain on the one-year risk for neck, shoulder, and lumbar pain. METHOD: A prospective study, using self-administered questionnaires, of a healthy cohort of 4,140 vocationally active persons ages 45-64, residing in
Histopathology Analysis of sentinel node biopsy - a single-institution experience supporting the use of serial sectioning and immunohistochemistry for detection of micrometastases by comparing four different histopathological laboratory protocols Aims: Detecting micrometastases (>0.2 and ≤2 mm/>200 cells) and isolated tumour cells (ITCs; ≤0.2 mm/<200 cells) is important for staging of breast canc
Sammanfattning Digitala övervakningskameror har tidigare använts inom fenologisk forskning för att kunna mäta grönskan i trädkronor. Man har under en längre tid kunnat koppla lövträdets årscykel till klimatförändringar och på så sätt haft ett starkt incitament att studera sambandet. I denna uppsats utforskas möjligheten att applicera metoden med digitalkameror på ett nyligen kalhugget område för aAbstract The use of inexpensive digital cameras in phenological research has been acclaimed since results in previous research have shown that they are reliable and precise in measuring greenness of vegetation. The work of this thesis aims to broaden the applicability by studying how well the method performs when measuring the regrowth of a clear-cut area. This is needed to complement existing res
Denna text undersöker de offentliga rättshjälpsmodellerna för icke-straffrättsliga frågor i Sverige och British Columbia (BC), Kanada. Den Svenska rättshjälpsmodellen karaktäriseras av att offentlig rättshjälp är subsidiär till privat rättsskyddsförsäkring. Undersökningen ger underlag för en komparativ analys. Med beaktande av utvecklingen sedan mitten av 1990-talet och den kritik som riktats mot This text examines the public legal aid models for non-criminal legal matters in Sweden and British Columbia (BC), Canada. The Swedish legal aid model is characterized by making public legal aid subsidiary to private Legal Expenses Insurance. The examination provides data for a comparative analysis. Considering developments since the mid 1990s, and the critique aimed at the legal aid models in bot
Under de senaste åren har uppmärksamheten kring Corporate Social Responsibility (CSR) utvecklats (Grankvist, 2009) i enlighet med den ökade köpintentionen för etiska attribut som konsumenter uttrycker (Becker-Olsen et al, 2006; Lee et al, 2010, 2005; Mai, 2014). Forskare har funnit att den höga köpintentionen (avsikten att köpa) för etiska attribut återspeglas inte i det faktiska köpbeteendet (utfCorporate Social Responsibility (CSR) has been gaining more attention in recent years (Grankvist, 2009) as consumers have indicated a strong support intention for ethical attributes (Becker-Olsen et al, 2006; Lee et al, 2010, 2005; Mai, 2014). Researchers have found that this support intention does not imply a strong correlation to purchase behavior (Carrigan and Attalla, 2001). In fact, the purch
A growing world population confronts humanity and the planet with several challenges due to its increased demand for food, space and energy, implying changes in land use. While agriculture currently provides enough food, it is destroying biodiversity and hence aggravates the planet ́s vulnerability to climate change. A paradigm shift might therefore be needed. Applying a political ecology lens, co
Head-and-neck tumors are often situated at an air-tissue interface what may result in an underdosage of part of the tumor in radiotherapy treatments using megavoltage photons. especially for small fields. In addition to effects of transient electronic disequilibrium, for these small fields, an increased lateral electron range in air will result in an important extra reduction of the central axis (
OBJECTIVE: To study the possibility of improving blood lipids, glucose tolerance and insulin sensitivity in women with impaired glucose tolerance and a history of gestational diabetes by merely changing the glycaemic index (GI) and dietary fibre (DF) content of their bread. DESIGN: Randomized crossover study where test subjects were given either low GI/high DF or high GI/low DF bread products duri
