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We present a new experimental method for the measurement of the compressibility of cells by analysis of free flow acoustophoresis separation data.

Background: The Self-Harm Antipathy Scale (SHAS) is a questionnaire designed to measure nurses’ attitudes towards self-harm. This can be useful to improve the quality of care provided to individuals who self-harm. Aim: The purpose of this study was to revise and adapt the SHAS for use in Sweden and evaluate the psychometric properties of this Swedish version (Self-Harm Antipathy Scale–Swedish Revi

Gasoline Partially Premixed Combustion (PPC) is a promising alternative combustion concept that can offer both high indicated efficiency and low exhaust emissions in terms of NOx and soot, compared to conventional diesel combustion (CDC). Previous research has shown that PPC can operate with gasoline-like fuels of varying RON numbers. Some of the most promising results come with the use of gasolin

Background: Psychosocial resources as well as lifestyle habits during pregnancy have been shown to effect the risk of having a small-for-gestational-age (SGA) child. Most previous studies are based on a single assessment of these exposures, which does not take into account the possibility of different effects during early add late stages of pregnancy. Methods: The impact of psychosocial and lifest

Bilden av den traditionella kärnfamiljen som enbart ett heterosexuellt gift par med barn ifrågasätts allt mer och andra familjekonstellationer blir allt vanligare. I detta kan vi se att homosexuella personers relationer och familjer har lyfts fram mer och mer och tidigare fördomar om dessa tolereras i mindre grad. Denna förändring i attityd sker dock i olika takt runtom i Europa, vilket gör EuropaThe traditional family as a heterosexual married couple with children is a norm that is increasingly being questioned and other family constellations are getting more common. In this context the relations and families of homosexual persons are being highlighted and prejudices against them are less tolerated. This change of attitude is occurring at different rates around Europe, which renders the t

Tasquinimod (a quinoline-3-carboxyamide) is a small molecule immunotherapy with demonstrated effects on the tumor microenvironment (TME) involving immunomodulation, anti-angiogenesis and inhibition of metastasis. A target molecule of tasquinimod is the inflammatory protein S100A9 which has been shown to affect the accumulation and function of suppressive myeloid cell subsets in tumors. Given the m

The objective of this thesis is to provide answers to how a method can be designed to gain better knowledge of how collaboration looks between different critical societal activities in a preparing and preventive stage related to the management of transboundary risks. The designed method consists of two parts; a technique for data acquisition, and a method for data analysis. In order to evaluate th

Background: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity. Here, we investigated cerebrospinal fluid (CSF) levels of PDGFR-β in suicide attempters and healthy controls and correlated PDGFR-β to depression symptom severity. Metho

The aim of this thesis is to study the flammability and fire spread for textile membranes for weather protection. This thesis includes literature studies to determine current standards and recommendations available. Main focus however have been on the European classification system EN 13501-1 and construction site safety. Two types of experimental tests have been done, cone calorimeter test and te

Organized human papillomavirus (HPV) vaccination was introduced in Sweden in 2012. On-demand vaccination was in effect from 2006 to 2011. We followed the HPV prevalences in Southern Sweden from 2008 to 2013.

Background: Summary statistics often hide individual patients' suffering, thereby impeding quality improvement efforts. Objectives: We aimed to show the experience of a population with health care toward the end of life while preserving the experience of the individual. Design: We developed a data display method called per-patient illness trajectory analysis. We tested it using a demonstration coh

There is a need of problematizing taken for granted assumptions in the conceptualization of collaborative housing when attempting to link collaborative housing and social integration. What are the difficulties and opportunities that migrants and non-migrants face in accessing collaborative housing projects? Addressing such type of questions will help to capture exclusionary processes affecting old

Background: Out-of-hospital cardiac arrest (OHCA) is a leading cause of death. Even if successfully resuscitated, mortality remains high due to ischemic and reperfusion injury (I/R). The oxygen deprivation leads to a metabolic derangement amplified upon reperfusion resulting in an uncontrolled generation of reactive oxygen species in the mitochondria triggering cell death mechanisms. The understan

Mandatory vaccination interferes with personal integrity but may be necessary to safeguard public health. However, states must consider all relevant factors in context and ensure such policies do not place disproportionate burdens on those hesitant about vaccination.

BACKGROUND: Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and total-tau protein (tau) are novel blood biomarkers of neurological injury, and may be used to predict outcomes in critical COVID-19.METHODS: A prospective multicentre cohort study of 117 consecutive and critically ill COVID-19 patients in six intensive care units (ICUs) in southern Sweden between May and Novem

Background Effective cooperation between B-cells and T-cells within the tumor microenvironment may lead to the regression of established tumors. B-cells and T-cells can recognize tumor antigens with exquisite specificity via their receptor complexes. Nevertheless, whether a diverse intratumoral B-cells and T-cell receptor (BCR, TCR) repertoire affects the tumor immune microenvironment (TIME) and c

INTRODUCTION: The incidence of pancreatic cancer is around 5 in 100,000, and the 5-year survival is poor. Pancreatic cancer patients have a high disease-specific burden of symptoms, and palliative chemotherapy has varying side effects. The American Society of Clinical Oncology (ASCO) suggests integrating specialized palliative care (SPC) with standard oncological treatment for pancreatic cancer pa

Place branding is defined as “the development of brands for geographic locationswith the aim of triggering positive associations about the area and distinguishinga place from other places” (Stevens et al., 2020, p. 752). Like all occupations,place branding is organised by discourses, or talk, that determine best practices andnorms about what constitutes expertise (Loacker and Sullivan, 2016). Expl