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Defects in the mitochondrial protein frataxin are responsible for Friedreich ataxia, a neurodegenerative and cardiac disease that affects 1:40,000 children. Here, we present the crystal structures of the iron-free and iron-loaded frataxin trimers, and a single-particle electron microscopy reconstruction of a 24 subunit oligomer. The structures reveal fundamental aspects of the frataxin mechanism.
Evaluating the trade interdependence among countries is the key to understanding critical metal minerals security. By constructing a novel interdependence network, this paper reveals a more comprehensive world hierarchy and risk system of critical metals, and focuses on the interdependencies between China and the US-led MSP countries before and after the Sino-US trade disputes. The results indicat
This paper presents a comparison of horizontal equity in health care utilization in 10 European countries and the US. It does not only extend previous work by using more recent data from a larger set of countries, but also uses new methods and presents disaggregated results by various types of care. In all countries, the lower-income groups are more intensive users of the health care system. But a
Despite the initial promise of immunotherapy for CNS disease, multiple recent clinical trials have failed. This may be due in part to characteristically low penetration of antibodies to cerebrospinal fluid (CSF) and brain parenchyma, resulting in poor target engagement. We here utilized transcranial macroscopic imaging to noninvasively evaluate in vivo delivery pathways of CSF fluorescent tracers.
Application fee or proof of fee exemptionIn order to have your application processed, non-EU citizens must pay the application fee by the deadline (early February if you are applying to autumn studies). If you have an EU citizenship or other exemption from the application fee, you must have submitted proof of this by the same deadline. Please note that your application will not be processed until
https://www.lunduniversity.lu.se/study/admission-degree-studies/applying-studies-when-apply/documentation - 2026-06-25
Here you’ll find key information about the nomination and application procedures for university-wide exchange agreements for the academic year 2026/2027. This Fact Sheet includes information on: Nomination and Application ProceduresCourse and Study RequirementsStudent AccommodationPreparations to ComeAdditional InformationKey Facts and VisionFind all relevant information about exchange studies on
