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One of the best systems for exploring the origin of enzyme catalysis has been the reaction of ketosteroid isomerase (KSI). Studies of the binding of phenolates to KSI have been taken as proof that the electrostatic preorganization effect only makes a minor contribution to the binding of the real, multiring, transition state (TS). However, our simulation study has determined that the difference bet
Purpose: There is a need for a simple, non-invasive, and easily accessible 3D imaging technique for the anophthalmic socket to create imaging data for future 3D printing of prostheses. This study aimed to investigate the feasibility of using a novel handheld tomographic ultrasound for 3D mapping of the anophthalmic socket. Methods: Ten anophthalmic sockets were scanned using a tomographic ultrasou
Background: Preterm and low birth weight infants are at an early stage of development, and do not receive adequate maternal circadian signals. They are often cared for over prolonged periods of hospitalisation in neonatal intensive care units (NICU), where environmental circadian stimuli are lacking. Exposure to artificial light–dark cycles may stimulate the development of the circadian system and
Decarbonization policies require public support to be implemented and to remain in legislation. Examinations of public support for climate policies tend to focus on asmall number of policy instruments and/or use hypothetical instead of real policy proposals. Here, we address these criticisms by examining public support acrossfour distinct policy instruments– command-and-control, market-based, info
This study bridges occupational health and innovation management by proposing psychosocial safety climate (PSC) as a key precondition for employee-driven innovation (EDI). EDI emphasises employees’ unique potential to generate and implement innovative ideas, with conducive working conditions, particularly those supporting psychological health, being crucial. Using a mixed-method explanatory design
This article addresses the issue of how Social Science and Humanities (SSH) researchers frame and argue relevance, where there are no explicit expectations to do so. It uses research project reports submitted to a Swedish research council, to distil and further analyze ‘relevance expressions’. These expressions illustrate some methodological differences along the lines of the long-standing distinc
The installation of a second RF cavity in the UVX electron storage ring at the Brazilian Synchrotron Light Laboratory (LNLS) at the end of 2003 brought about longitudinal instabilities driven by one of the HOMs of the new cavity. Even though the operational difficulties related to these unstable modes were successfully overcome by means of a combination of cavity tuning (using temperature and plun
BackgroundThe impact of season when determining a serum 25-hydroxyvitamin D (S-25OHD) cut-off level for optimal bone health is unknown.ObjectiveTo investigate the relative importance of S-25OHD for bone mineral density (BMD) by season.MethodsA subcohort of 5002 Swedish women (mean age 68 years), randomly selected from a large population-based longitudinal cohort study with repeat dietary and lifes
Guest editors of special issue with Ecology and Society
Precise diagnostic on the electron beam parameters is a very valuable tool and essential in the operation of synchrotron light sources. One possible option is to employ the emitted synchrotron radiation for non-destructive measurements. A tool, which has been used in many ring-based synchrotron light sources is Time-Correlated Single-Photon Counting (TCSPC). It allows to measure the arrival time d
Precarious, flexibilised and informalised work has been a norm rather than the exception. Globally, formal employment, with a job contract, sick leave, vacation, rights to safe workspace, defined working hours, etc., has only been a reality for a minority. Much of the global workforce work outside formalised workspaces which include all types of economic activities deemed as ‘informal’, such as, s
Recent research in evolutionary economic geography addressing radical innovation and grand challenges has advocated for a shift in focus from single technologies and products toward interrelated configurations of technologies and institutions. This suggests moving beyond explaining innovation and industrial dynamics primarily by the existence of appropriate knowledge and capability stocks, to incl
This article investigates the performance of several residuals for the Cox proportional hazards regression model to diagnose the influential observations. The standardized and adjusted forms of residuals are proposed for Cox proportional hazards regression model. In addition, Cook’s distance is proposed for both standardized and adjusted residuals. The assessment of different residuals for the ide
In recent decades there has been an increasing demand in environmental sciences for harmonized climatic data at large spatial scales and long periods. Here we present easyclimate, a software package to obtain daily climatic data at high resolution (0.0083°, ∼1 km) with R. The package facilitates the downloading and processing of precipitation, minimum and maximum temperatures for Europe from 1950
Excessive daytime sleepiness (EDS) is a common complaint in the general population and is associated with cardiovascular disease and increased mortality. We aimed to investigate whether sleep duration is related to excessive daytime sleepiness in the general population, both in itself and in combination with other factors. We performed a cross-sectional analysis in the population-based Swedish CAr
Given that urban planning has served colonial and imperialist purposes, this commentary explores the existing challenges for early-career researchers conducting research designed in the Global North and carried out in/on the Global South. We offer a series of questions and provocations as an invitation to colleagues facing similar dilemmas to reflect on their own research from a decolonial methodo
High-pressure homogenizers are prone to cavitation, which causes wear and influences breakup efficiency. However, the inception point, as well as the extent and intensity, depends on geometry, operation, and fluid properties. While several methods have been previously suggested to characterize cavitation in homogenizer valves (including ultrasonic methods), they have required highly specialized, s
This is a poster presentation of the project RIGHydro for the MissionGreenFuels Annual Meeting 2025. The project RIGHydro is funded by the Innovation Fund Denmark.The Project "Regulatory Innovation to Incentivize Green Hydrogen" (RIGHydro) aims to contribute to the deployment of green hydrogen as a key component of the green transition in Denmark, the EU and beyond. Through an analysis of the late
