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Healthy eye lenses are transparent and flexible, able to adapt shape in order to focus on far away and close-by objects. With age, however, this flexibility is lost, leading to a condition known as presbyopia. This vision disorder where close-by objects appear blurred commonly starts around the age of 40. The aim of this thesis is to elucidate the molecular origin of the gradual hardening of the c
Methods: Drug-induced interstitial lung disease (ILD) is crucial to detect early to achieve the best treatment outcome. Optimally, non-invasive imaging biomarkers can be used for early detection of disease progression and treatment follow-up. Therefore, reliable in vivo models are warranted in new imaging biomarker development to accelerate better-targeted treatment options. Single-dose bleomycin
Efficient systemic pharmacological treatment of solid tumors is hampered by inadequate tumor concentration of cytostatics necessitating development of smart local drug delivery systems. To overcome this, we demonstrate that doxorubicin (DOX), a cornerstone drug used for osteosarcoma treatment, shows reversible accretion to hydroxyapatite (HA) of both nano (nHA) and micro (mHA) size. nHA particles
This work presents an automated method for comprehensively analyzing EPID images acquired for quality assurance of RapidArc® treatment delivery. In-house-developed software has been used for the analysis and long-term results from measurements on three linacs are presented.
Membrane proteins play several important roles in a cell. Among these proteins are aquaporins (AQPs) and transient receptor potential (TRP) ion channels that mediate water transport, temperature and noxious chemical sensation, respectively. The function of some AQPs, for example the spinach isoform SoPIP2;1 is regulated by pH, phosphorylation and heavy metals such as mercury. However, the mechanis
Oxidation reactions are important in organic chemistry as well as in nature. In industry, oxidations are commonly used for the synthesis of chemicals and pharmaceuticals, however such processes have a number of limitations, they use chlorinated solvents, stoichiometric oxidation reagents, and in some cases the reagents that have risks of explosion during transportation and storage. This has called
Public squares are everyday life-spaces, essential for supporting social interaction and thereby contributing to individuals’ wellbeing and quality of life. The provision of safe, accessible, and inclusive public squares is an imperative for sustainable urban development of cities and communities.After dark, electric lighting is necessary for sustaining activities, including social interaction, in
MILJÖVETENSKAP Preliminärt schema 2022-10-07 Kurs: Styrning och styrmedel för en hållbar ekonomi (MVES02) Kursansvarig: Carl Dalhammar Lärare: Carl Dalhammar (CD), Leonidas Milios (LM), Sofie Sandin (SS), Anna-Riikka Kojonsaari (ARK), Lars Hansson (LH), Cornelia Hartman (CH), Hanna Axelsson (HA) Lokaler: Samtliga lektioner och seminarier hålls på IIIEE. De flesta i rum 133 el rum 139 som ligger på
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2022-10/Schema%20MVES02%20HT22,%20221007.pdf - 2026-07-16
