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Objective: Intrapartum antibiotic prophylaxis (IAP) reduces the incidence of neonatal early onset group B streptococcal infections. The present study investigated if an automated PCR-assay, used bedside by the labor ward personnel was manageable and could decrease the use of IAP in a setting with a risk-based IAP strategy. Methods: The study comprises two phases. Phase 1 was a multicenter, randomi

Vår grupp studerar olika höftsjukdomar med debut i barndomen och deras association med framtida höftbesvär och artros. 1) Höftdysplasi är en omogenhet i höftleden som innefattar patientgrupper från nyfödda till vuxna. 2) Femuroacetabulärt impingement (FAI) är en anatomisk avvikelse i höftleden. 3) Fysiolys, är en glidning i höftkulans tillväxtzon hos tonåringar som oftast är: a. kronisk eller Our group investigates hip joint diseases that start during childhood but may result in impaired function and OA in adulthood. 1) Hip dysplasia ranges from congenital dislocation to dysplasia in adults. 2) Femuroacetabulärt impingement (FAI) is developmental anatomical deformity. 3) Slipped Capital Femoral Epiphysis (SCFE) is a slip in the growth plate of the femoral head, most commonly: a. Chro

Systemisk skleros, SSc, är en ovanlig reumatologisk sjukdom där immunologisk aktivering leder till kärlskada och fibros i hud och inre organ. Hälften av patienterna avlider av komplikationer från hjärta eller lungor, ofta fibros i lungor eller pulmonell arteriell hypertension (PAH). Projekten rör kartläggning av tidiga mekanismer kring patogenes och biomarkörer för tidig diagnos och monitorering aSystemic sclerosis, SSc, is a rare rheumatologic disease where immun activation leads to vascular damage and fibrosis in skin and internal organs. Half of the population will die from complications from heart or lungs, mostly lung fibrosis or pulmonary arterial hypertension (PAH). Our projects aim at early pathogenic mechanisms and biomarkers for early diagnosis and to monitor the disease and the

Sepsis (när en infektion blir livshotande) är en bortglömd folksjukdom som drabbar lika många som cancer och har högre dödlighet än hjärtinfarkt och är mycket dyrt. Sepsis är ett komplext syndrom och borde precis som cancer inte klassas som en sjukdom utan många olika beroende på vilken bakterie som orsakar infektionen, vilket organ infektionen först drabbar och kanske viktigast av allt i vilket iSepsis (when an infection becomes life threatening) is a neglected public health problem affecting as many as cancer, with a higher mortality rate than myocardial infarction and is very expensive. Sepsis is a complex syndrome, akin cancer and should not be classified as a single disease, rather many different depending on 1. the bacteria causing the infection, 2. Organ focus of the infection, and

Introduction: Flexible Assertive Community Treatment (FACT) is implemented in Swedish general Mental Health Services. While FACT focuses on supporting the participation and personal recovery of individuals with complex mental health needs, critical components enabling these aspects are poorly understood. The aim of this study was to understand the critical components of FACT delivery supporting pa

The Swedish Stroke Register (Riksstroke) was founded in 1994. Riksstroke includes registration of acute stroke, with a follow up after 3 months and 1 year. The Stroke policy and quality register research group has several ongoing projects based on data from Riksstroke, and in many studies also using data record linkage to other national registers and data bases. The thesis of Teresa Ullberg expl

Purpose We describe the key elements of early palliative care (PC) across the illness trajectory and examine whether visit content was associated with patient-reported outcomes and end-of-life care. Methods We performed a secondary analysis of patients with newly diagnosed advanced lung or noncolorectal GI cancer (N = 171) who were randomly assigned to receive early PC. Participants attended at le