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The human brm (hbrm) protein (homologue of the Drosophila melanogaster brahma and Saccharomyces cervisiae SNF-2 proteins) is part of a polypeptide complex believed to regulate chromatin conformation. We have shown that the hbrm protein is cleaved in NB4 leukemic cells after induction of apoptosis by UV-irradiation, DNA damaging agents, or staurosporine. Because hbrm is found only in the nucleus, w
Although N- and P-type Ca2+ channels predominant in fast-secreting systems, Lc-type Ca2+ channels (C-class) can play a similar role in certain secretory cells and synapses. For example, in retinal bipolar cells, Ca2+ entry through the Lc channels triggers ultrafast exocytosis, and in pancreatic beta-cells, evoked secretion is highly sensitive to Ca2+. These findings suggest that a rapidly release
We investigate the occurrence of water vapour signatures in a total of 10 red giants in the solar neighbourhood at mid-infrared wavelengths (12 pm). With the use of high resolution spectra from TEXES and synthesized spectra based on MARCS model atmospheres, we analyse the differences and discuss plausible causes. These include abundance adjustments, the addition of non-photospheric components (MOL
We show that computation of all-terminal graph reliability requires time exponential in Ω(m/ log2 m) for simple graphs of m edges under the Exponential Time Hypothesis.
How can schools influence the viewpoints students hold on aids and sex? The investigation focused on teaching the subject of aids and sex to secondary school students in grades eight through eleven. Thirteen teachers and their students, in 15 different classes, were studied and compared with a control group; altogether 548 students were included in the investigation. The aim of the study was to de
This article studies the Kyoto Protocol’s CDM as an example of hybrid governance, involving both public and private actors, and uses the concept of agency to explore the influence of public and private actors in the governance of the CDM over time. Even though public actors formally govern the CDM, the delegation of project implementation and supervision to private companies has created ample oppo
Vita brevis, ars longa (or...life is too short for abstracts).
This paper examines the uncovered interest rate parity (UIP) and extends the analysis in Spronk, Verschoor and Zwinkels (2013) by looking at the UIP between Sweden and the United Kingdom. The flaws of the UIP and the reasons for why it does not seem to hold, has been called the UIP puzzle. The thesis tests if the UIP puzzle can be explained by constructing a heterogeneous agent model with a carry
This essay is concerned with whether the progressive aspect is overgeneralized by children, using it with stative verbs. The study targets the age interval 1 to 10 years and adults. The matter was investigated in several child corpora and adult corpora. The interval 1 to 5 years was covered by the Brown (1973b) corpus with Eve, Adam and Sarah. Data for the interval 6 to 10 years were obtained from
The European Commission’s Decisions addressing tax rulings which came into the public domain in November 2014 as constituting State Aid (contrary to Article 107 TFUE) after Lux-Leaks have generated some discussion. Of paramount interest in this thesis is the Commission’s declaration in the Belgium Excess Profits, Fiat and Starbucks Decisions that the European Union has its own ALP (hereinafter cal
This paper analyses the prevalence of populist rhetoric within the South African ruling ANC party by evaluating the speeches of five presidents through an ideational theoretical framework. The grading criteria applied was developed by Hawkins et al. 2019, widely regarded as a pioneers in the field of populism studies. All the evaluated speeches in this paper were State Nation Addresses (SONAs) and
Personal growth as a process remains vaguely understood. We introduce the Personal Growth Process (PGP) model based on Carl Rogers’s organismic valuing process (OVP). The PGP model explains personal growth as a sociocognitive embodied process whereby an individual undergoes multiple mental shifts that make up an ongoing, fluctuating process over the long term, starting from a place of psychologica
The discovery, at the beginning of the 20th century, that elements can transform into other elements, due to the spontaneous decay of an instable to a stable atomic nuclei, gave rise to a powerful source for age information in many fields of earth science. For impact structures, it is crucial to establish well-defined and precise ages in order to understand how impact events affect the Earth’s geo
