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Background: Advanced interatrial block (aIAB), which is associated with incident atrial fibrillation and stroke, occurs in the setting of blocked interatrial conduction. Atrial amyloid deposition could be a possible substrate for reduced interatrial conduction, but the prevalence of aIAB in patients with transthyretin cardiac amyloidosis (ATTR-CA) is unknown. We aimed to describe the prevalence of
Aims: To investigate what NSE levels predict long-term neurological prognosis at 24, 48 and 72 hours after ROSC in a cohort of out-of-hospital cardiac arrest and to validate previously suggested NSE cut-offs, including the latest ERC guidelines (2021). Methods: Patients admitted to intensive care units in four hospitals in Southern Sweden between 2014–2018 were included. Blood samples were handled
The dense accumulation of α-Synuclein fibrils in neurons is considered to be strongly associated with Parkinson’s disease. These intracellular inclusions, called Lewy bodies, also contain significant amounts of lipids. To better understand such accumulations, it should be important to study α-Synuclein fibril formation under conditions where the fibrils lump together, mimicking what is observed in
In this article, a novel vector network analyzer (VNA)-based ultrawideband (UWB) channel sounder using radio-over-fiber (RoF) techniques is presented. Benefiting from the usage of optical fiber cable, the measurement range and the dynamic range are significantly increased compared with the conventional coaxial-based VNA system. Specifically, using RoF increases the dynamic range to a maximum of 11
Immersive virtual reality (IVR) provides great potential to experimentally investigate effects of peers on student learning in class and to strategically deploy virtual peer learners to improve learning. The present study examined how three social-related classroom configurations (i.e., students' position in the classroom, visualization style of virtual avatars, and virtual classmates' performance
Fire behaviour is changing in many regions worldwide. However, nonlinear interactions between fire weather, fuel, land use, management and ignitions have impeded formal attribution of global burned area changes. Here, we demonstrate that climate change increasingly explains regional burned area patterns, using an ensemble of global fire models. The simulations show that climate change increased gl
We report the first large-scale retrospective cohort study on adolescent and young adult (AYA) polycythemia vera (PV) and essential thrombocythemia (ET) in Japan, a subgroup analysis using Japanese multicenter registry data (JSH-MPN-R18). This study included patients with PV (n = 31) or ET (n = 141) aged 20 to 39 years at the initial visit. Hemorrhage-free survival (HFS) was better in AYA ET than
We have previously performed empirical valence bond calculations of the kinetic activation barriers, Δ G‡calc, for the deprotonation of complexes between TIM and the whole substrate glyceraldehyde-3-phosphate (GAP, Kulkarni et al. J. Am. Chem. Soc. 2017 , 139 , 10514 - 10525 ). We now extend this work to also study the deprotonation of the substrate pieces glycolaldehyde (GA) and GA·HPi [HPi = pho
The aim of this study is to investigate the association between self-perceived voice problems and social participation among older adults (65-80 years). A complementary aim was to investigate the association between self-perceived voice problems and physical activity. Method Participants were recruited through social media and asked to complete an online questionnaire. In total, 152 individuals we
Northern peatlands store 300–600 Pg C, of which approximately half are underlain by permafrost. Climate warming and, in some regions, soil drying from enhanced evaporation are progressively threatening this large carbon stock. Here, we assess future CO2 and CH4 fluxes from northern peatlands using five land surface models that explicitly include representation of peatland processes. Under Represen
Railway traffic is growing, resulting in a highly interconnected train network. Due to the interdependence between trains’ activities, a better understanding of train passes and their effects can ensure dispatching decisions made have minimum risk of delays. The impacts of train pass on dwell time delays were investigated using historical Swedish railway operation data. Three scenarios were consid
The hospital morbidity and mortality of 100 patients operated with two internal thoracic arteries with or without additional vein grafts (BITA group) were compared with a matched group of 100 patients operated with one left internal thoracic artery (ITA) on the anterior descending artery with additional vein grafts (LITA control group). In each study group, 3% of the patients had diabetes mellitus
In the Ordovician limestone of the Thorsberg quarry (South Sweden), about 130 meteorites have been found. Among the extraterrestrial material, several terrestrial Cr-spinels and zircons have been found too. In particular, in the interval 416–447 cm above the Arkeologen bed, terrestrial Cr-spinels, compositionally different from previous studied Cr-spinels of the same sequence, are present. Previou
Protected area networks help species respond to climate warming. However, the contribution of a site's environmental and conservation-relevant characteristics to these responses is not well understood. We investigated how composition of nonbreeding waterbird communities (97 species) in the European Union Natura 2000 (N2K) network (3018 sites) changed in response to increases in temperature over 25
We compared, head-to-head, the old generation Actigraph model 7164 with the new generation Actigraph GT1M accelerometer. A total of 15 randomly selected teenagers (eight girls and seven boys) were investigated. They performed a treadmill test wearing the two kinds of accelerometers around the waist simultaneously. The treadmill test consisted of three different levels of speed 4, 6 and 8 km h(-1)
Aim: Acute otitis media (AOM) is a common childhood disease, which often becomes recurrent (rAOM). A small reduction of AOM episodes has been noted in unselected child cohorts after vaccination with heptavalent conjugate pneumococcal vaccine (PCV7). The purpose of this study was to investigate how vaccination affects young children at risk of developing rAOM. Methods: Ninety-six children with an A
Objective: The aim of this study was to assess the incremental cost-effectiveness of on-demand versus prophylactic hemophilia therapy in Iran from a third-party payers’ perspective.Methods: A retrospective chart review of twenty-five type A hemophiliacs who were treated in three hemophilia treatment centers was conducted. The patients were boys 0–9 years old receiving one of two treatments: (i) pr
This paper presents a radio frequency front-end (RFFE) comprised of a cascode low-noise amplifier (LNA) and a reconfigurable Q-enhanced filter. Employing a dual-resonant input matching network, the LNA attains a significantly wide bandwidth. The filter consists of four Q-enhanced resonators enabling three modes of operation: 1) dual-band filter, 2) single band-pass filter (BPF) along with a tunabl
It is universally acknowledged that highly photosensitive transistors are strongly dependent on the high carrier mobility of polymer-based semiconductors. However, the polymer π–π stacking and aggregation, required to increase the charge mobility, conversely inhibit the dissociation of photogenerated charge carriers, in turn accelerating the geminate recombination of electron-hole pairs. To explor
