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The Events Research Programme (ERP) was a multi-disciplinary study undertaken during the COVID-19 pandemic to investigate SARS-CoV-2 transmission risks and mitigations around the reopening of mass events in the UK in 2021 – including a behavioural study, exploring how non-pharmaceutical interventions (NPIs), such as social distancing, pre-event virus testing, and the use of face coverings might en
The bone marrow (BM) niche is a complex cellular, molecular, and physical microenvironment capable of homing and supporting hematopoiesis. It is characterized by its ability both maintain and to drive hematopoietic stem and progenitor cells (HSPCs) self-renewal and differentiation which ultimately generate all blood cell types. However, how the niche elements interact in a human context remains la
As a research domain, the smart city keeps growing, despite the remaining contradictions and ambiguity related to its conceptual aspects. We propose to dig deeper into the complex socio-technical nature of the smart city and examine the concept through the lens of different public governance paradigms, therefore aligning it with the sustainability outcomes. Embracing interrelated dimensions of hum
We present a method that allows enabling matrix element corrections (MECs) in Pythia8 with MC@NLO matching, without incurring double counting. MECs are an interesting feature that may contribute to the accuracy of theoretical predictions, alongside matching and merging. We directly compare our method to a specific choice of settings in Pythia8, which can remove double-counting for MECs in certain
Tetrodotoxin (TTX) is a marine toxin responsible for many intoxications around the world. Its presence in some pufferfish species and, as recently reported, in shellfish, poses a serious health concern. Although TTX is not routinely monitored, there is a need for fast, sensitive, reliable, and simple methods for its detection and quantification. In this work, we describe the use of an automated pa
Objective: Emerging research suggests that rheumatoid arthritis (RA) is associated with intestinal dysbiosis. This prospective pilot study evaluates changes in intestinal microbial composition in patients with RA initiating treatment with either methotrexate (MTX) or a tumor necrosis factor inhibitor (TNFi). Methods: Consecutive patients, fulfilling the 2010 American College of Rheumatology/EULAR
Ethylene is one of the most important products in the emissions-intensive petrochemical industry. Decarbonizing the ethylene industry is thus important for achieving global carbon neutrality. This study is the first to explore future long-term zero-emissions production pathways for the ethylene industry in China, the world's biggest ethylene producer. An optimization model was built in the context
In this Perspective, we discuss thermal imbalance and the associated electron-mediated thermal transport in quantum electronic devices at very low temperatures. We first present the theoretical approaches describing heat transport in nanoscale conductors at low temperatures, in which quantum confinement and interactions play an important role. We then discuss the experimental techniques for genera
In this paper, a factor-augmented version of the New Keynesian Phillips curve (NKPC) is assessed using a data set comprised of a large panel of European Union (EU) member countries. The factor-augmentation is natural given that country-level inflation rates are highly co-moving. The presence of unattended common factors is important because it raises the issue of omitted variables bias, as the rea
The introduction of autonomous machines (AMs) in human domains has raised challenging questions about the attribution of responsibility; referred to as the responsibility gap. In this paper, we address the gap by arguing that entities should not be granted the freedom of action unless they can also recognise the same right for others—and be subject to blame or punishment in cases of undermining th
Microbial, algal, plant and animal cells have been immobilized, with preserved viability, by entrapment in various matrices according to a new bead polymerization technique. The cell polymer/monomer mixture is kept suspended in a hydrophobic phase such as soy, paraffin, or silicon oil, tri-n-butylphosphate, or dibutyphtalate, which is compatible with the cells. The various monomers or polymers tes
Parkinson's disease (PD) is characterized by the loss of the dopaminergic nigrostriatal pathway which has led to the successful development of drug therapies that replace or stimulate this network pharmacologically. Although these drugs work well in the early stages of the disease, over time they produce side effects along with less consistent clinical benefits to the person with Parkinson's (PwP)
In this project I investigate how architecture can give form to an institution that creates the conditions for negotiation between competing narratives. It is situated at Sillhovstomten, the contested site behind the Nationalmuseum in central Stockholm. The failed Nobel Center proposal on this site revealed that it is not an empty void awaiting to be filled, but a place where different political,
Background: Dietary management of phenylketonuria (PKU) focuses on restricting phenylalanine (Phe) intake. The European PKU guidelines and the PKU Dietary Handbook recommend a simplified PKU diet, allowing unrestricted consumption of many low-Phe foods, called free foods. While this approach may reduce the treatment burden for patients, its implementation varies. This study investigated practi
Recent advances in the field of wild avian microbiome research have significantly deepened our understanding of the eco-evolutionary dynamics of bird–microbe interactions. Consequently, the field is now approaching a pivotal moment in uncovering the ultimate factors shaping avian microbiome structure, especially in relation to birds' ecological, evolutionary, and dietary diversity. Yet, avian micr
Global manufacturing companies operate in increasingly uncertain and complex environments where changes in sourcing strategies, supplier structures and logistics networks create significant challenges for decision- making. Traditional analytical methods often struggle to capture the dynamic and interconnected nature of modern supply chains, limiting their ability to support proactive evaluation
we present rearing records of Eulophidae resulting from five years of collecting leafminers and other herbivorous insects throughout the United States. These include the first documented hosts for Chrysocharis beckeri Yoshimoto, C. minuta (hansson), Closterocerus damastes walker (identification tentative), Diaulinopsis albiscapus (girault), Elasmus borrowi girault, Neochrysocharis cyaneoviridis ha
Studying successional processes and related factors in salt marshes encompasses both fundamental (community structuration) and applied (biodiversity conservation and restoration) issues. Current managed realignment projects and sites where, in the past, large storm events led to breaches in embankments create unique experimental conditions for such challenges by re-instating tidal inundation and s
Often in clinical practice, a diagnosis of alcohol dependence or abuse does not provide enough information to establish an adequate treatment plan. Hence, multidimensional instruments have been constructed better to describe the extent and character of a patient's alcohol problem. The purpose of the current article is to present the AVI-R2, a self-report test that provides a standardized and diffe
