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In the last 15 years or so, soft selective sweep mechanisms have been catapulted from a curiosity of little evolutionary importance to a ubiquitous mechanism claimed to explain most adaptive evolution and, in some cases, most evolution. This transformation was aided by a series of articles by Daniel Schrider and Andrew Kern. Within this series, a paper entitled “Soft sweeps are the dominant mode o
In order to produce a more efficient design of a compact turbine driving a cryogenic engine turbo-pump for a satellite delivering rocket, a new supersonic loss model is proposed. The new model was constructed based on high-quality published data, composed of Schlieren photographs and experimental measurements, that combined provided a unique insight into the mechanisms driving supersonic losses. U
Deoxyribonucleoside kinases are feedback inhibited by the final products of the salvage pathway, the deoxyribonucleoside triphosphates. In the present study, the mechanism of feedback inhibition is presented based on the crystal structure of a complex between the fruit fly deoxyribonucleoside kinase and its feedback inhibitor deoxythymidine triphosphate. The inhibitor was found to be bound as a bi
The Iranian Light Source Facility is a fourth-generation low emittance synchrotron light source under development in Iran. The design and in-house fabrication of RF cavities are key elements of this project. The choice of 100 MHz capacity loaded RF cavities offers many advantages compared to other cavity types due to a simpler geometry, ease of fabrication, and lower costs for manufacturing and RF
Fatigue safety verification of existing bridges that uses ''re-calculation'' based on codes, usually results in insufficient fatigue safety, triggering invasive interventions. Instead of “re-calculation”, Structural Health Monitoring (SHM) should be used for the assessment of the existing bridges. Monitoring systems provide data that can reduce uncertainties associated with the fatigue loading pro
To estimate in gynecologically asymptomatic postmenopausal women with and without hormone replacement therapy (HRT) the prevalence at transvaginal ultrasound examination of 1) endometrial thickness ≥5.0mm, 2) intrauterine focal lesions if endometrial thickness ≥5.0mm, and 3) premalignant and malignant changes in the endometrium if endometrial thickness is ≥5.0mm and intrauterine focal lesions are
OBJECTIVES: To determine the agreement between transvaginal ultrasound examinations performed before and at saline contrast sonohysterography (SCSH) with regard to number, size and shape of Cesarean section (CS) scar defects. METHODS: In all, 108 women underwent transvaginal ultrasound examination with SCSH at least 6 months after CS: 68 had undergone one CS, 32 two CSs and eight women had undergo
The Corded Ware Culture complex in Sweden involves a special form of social structure called the Battle Axe Culture. Among well-known features, such as single graves, there are also other forms of expression. A special form of find is illustrated by a place with a significant accumulation of deliberately burned or otherwise destroyed objects. This mass deposit includes both well-known object forms
As we become increasingly conscious of the entangled nature of human existence, we need to become more attuned to the needs of other species, and things on this planet we are bound to. This presents us with an opportunity to rethink in whose interest we approach architectural design, and to bring vital voices into the process that have – until now – been unable to make themselves heard. We conduct
In 2022 and 2023, the Large Hadron Collider produced approximately two billion hadronic interactions each second from bunches of protons that collide at a rate of 40 MHz. The ATLAS trigger system is used to reduce this rate to a few kHz for recording. Selections based on hadronic jets, their energy, and event topology reduce the rate to Ô(10) kHz while maintaining high efficiencies for important s
