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Impact of longer term phosphorus control on cardiovascular mortality in hemodialysis patients using an area under the curve approach : results from the DOPPS

BACKGROUND: Serial assessment of phosphorus is currently recommended by the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, but its additional value versus a single measurement is uncertain. METHODS: We studied data from 17 414 HD patients in the Dialysis Outcomes and Practice Patterns Study, a prospective cohort study, and calculated the area under the curve (AUC) by multiplying the

Preterm or early term birth and risk of autism

OBJECTIVES: Preterm birth has been linked with increased risk of autism spectrum disorder (ASD); however, potential causality, sex-specific differences, and association with early term birth are unclear. We examined whether preterm and early term birth are associated with ASD in a large population-based cohort. METHODS: A national cohort study was conducted of all 4 061 795 singleton infants born

Quality Assurance in Radiotherapy - Development and evaluation of new tools for improved patient safety

Popular Abstract in Swedish Strålbehandling är en av de vanligaste behandlingarna mot cancer. Hälften av alla behandlingar syftar till att bota patienten från sjukdomen, men strålbehandling är även en mycket effektiv behandling för att lindra smärta och andra symptom för patienter med en obotlig cancer. Förberedelse inför strålbehandling är en komplicerad procedur, som innefattar många olika teknPreparation for radiotherapy is a complex procedure that involves many different technologies and groups of professionals. The rapid development and introduction of new technologies throughout the last decade have made it possible to deliver highly conformal, individually-shaped dose distributions with high accuracy. However, there is widespread concern that current quality assurance practices hav

Measurements of Function in Children with Cerebral Palsy

Popular Abstract in Swedish Cerebral pares (CP) drabbar drygt 2 barn per 1000 födda och är den vanligaste orsaken till rörelsehinder hos barn och ungdomar. På latin betyder CP "förlamning från hjärnan" och är ett samlingsnamn för ett följdtillstånd efter en skada i den omogna hjärnan under dess utveckling från fosterstadiet t o m 2-års ålder. Skadan är av engångskaraktär men de olika symtomen föräCerebral palsy (CP) is a term for a group of conditions associated with motor disabilities, that are very heterogeneous, i.e. symptoms, severity, associated impairments, functional outcome and needs. The overall purpose of this thesis was to study the prevalence and gross motor function and to evaluate and adapt measurements in children with CP. The prevalence in Southern Sweden was 2.4 per 1000 c

A Comparative Study of Railway Planning, Operations and Delays in Japan and Sweden

Japan is well-renowned in the international community for its expertise in high-capacity, punctual railway operations. Particularly the high-speed trains, the Shinkansen, are very well known and respected internationally, but the knowledge outside Japan is more limited regarding more conventional lines, commuter trains, and the metro. Despite this, during rush hours trains in the Tokyo area can be

External validation of the CREST model to predict early circulatory-etiology death after out-of-hospital cardiac arrest without initial ST-segment elevation myocardial infarction

Background: The CREST model is a prediction model, quantitating the risk of circulatory-etiology death (CED) after cardiac arrest based on variables available at hospital admission, and intend to guide the triage of comatose patients without ST-segment-elevation myocardial infarction after successful cardiopulmonary resuscitation. This study assessed performance of the CREST model in the Target Te

Placenta-associated adverse pregnancy outcomes in women experiencing mild or severe hyperemesis gravidarum – a systematic review and meta-analysis

Background: Nausea and vomiting in pregnancy (NVP) affects 50–80% of pregnant women and is correlated to the level of human chorionic gonadotropin (hCG). Hyperemesis gravidarum (HG) is a severe condition, with an incidence of 0.2–1.5%, characterized by consistent nausea, vomiting, weight loss and dehydration continuing after the second trimester. Aim: The aim of this systematic review was to inves

Deep learning for rapid and reproducible histology scoring of lung injury in a porcine model

Acute respiratory distress syndrome (ARDS) is a life-threatening condition with mortality rates between 30-50%. Although in vitro models replicate some aspects of ARDS, small and large animal models remain the primary research tools due to the multifactorial nature of the disease. When using these animal models, histology serves as the gold standard method to confirm lung injury and exclude other

Risk factors for intracerebral haemorrhage – Results from a prospective population-based study

Introduction: While the relationship between hypertension and incident intracerebral haemorrhage is well established, other risk factors are less clear. This study examined risk factors for primary intracerebral haemorrhage, separately for lobar and non-lobar intracerebral haemorrhage. Patients and methods: Incidence of intracerebral haemorrhage was studied among 28,416 individuals from the popula

The CHEOPS mission

The CHaracterising ExOPlanet Satellite (CHEOPS) was selected on October 19, 2012, as the first small mission (S-mission) in the ESA Science Programme and successfully launched on December 18, 2019, as a secondary passenger on a Soyuz-Fregat rocket from Kourou, French Guiana. CHEOPS is a partnership between ESA and Switzerland with important contributions by ten additional ESA Member States. CHEOPS

Combustion sensitivity to the nozzle hole size in an active pre-chamber ultra-lean heavy-duty natural gas engine

Active pre-chamber configurations are considered a valuable solution for improving the operation of the internal combustion engine, in the view to overcome the many challenges it has been made to face. Combining this technology with the use of natural gas, a fuel that has increasing availability and interest in the market share, it is possible to burn ultra-lean mixtures (with air-to-fuel ratios,

Combining in-cylinder pressure and 1D simulation tools to understand the combustion characteristics of natural gas in pre-chamber ignition systems for energy generation

Recent outlooks suggest a long-term relevance of internal combustion engines for both power generation and transportation. Nonetheless, stringent pollutant reduction requirements combined with new CO2 mandates draws a challenging scenario, requiring intensive research and development activities to develop and optimize combustion modes to fulfill these requirements. Among the recent advancements, t

A FrameNet-based semantic role labeler for Swedish

We present a FrameNet-based semantic role labeling system for Swedish text. As training data for the system, we used an annotated corpus that we produced by transferring FrameNet annotation from the English side to the Swedish side in a parallel corpus. In addition, we describe two frame element bracketing algorithms that are suitable when no robust constituent parsers are available. We evaluated

Lexical and Acoustic Modelling of Swedish Prosody

Popular Abstract in Swedish Prosodi och intonation är viktiga delar i det mänskliga talet. I system för text-till-talomvandling och automatisk taligenkänning måste prosodiska modeller inkluderas för att uppnå acceptabla resultat. Denna avhandling bidrar till modelleringen av svensk prosodi ur lexikalt och akustiskt perspektiv. Tre aspekter av lexikal modellering av prosodi studeras. Vi skisserar Prosody and intonation are very important ingredients of human speech. In speech technology, text-to-speech (TTS) and automatic speech recognition (ASR) systems must incorporate prosodic models in order to reach acceptable performances. We contribute to the modelling of Swedish prosody in a speech technology context from lexical and acoustic angles. Three aspects of lexical prosodic modelling are

The Stockholm Festival, 1966

The article is an introduction to the festival 'Visioner av Nuet' Stockholm, 1966. The article focuses on the historical event, and contextualizes it to both the discussions on art and technology at the time, and to the planned collaborations with the prominent artists from the American group E.A.T. such as Billy Klüver, John Cage, Robert Rauchenberg and Öyvind Fahlström, - collaborations that nev

Preparing for a Digital Twin at Alfa Laval

Problem description: Alfa Laval, a global leader in providing solutions for heat transfer, separation, and fluid handling, seeks to improve production scheduling at their component factory in Lund. They aim to digitalise the process by developing a digital twin (DT), a virtual model of the manufacturing system. The DT will simulate production flow to support decision-making and optimise scheduling