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Hybrid SSF/SHF Processing of SO2 Pretreated Wheat Straw—Tuning Co-fermentation by Yeast Inoculum Size and Hydrolysis Time

Wheat straw is one of the main agricultural residues of interest for bioethanol production. This work examines conversion of steam-pretreated wheat straw (using SO2 as a catalyst) in a hybrid process consisting of a short enzymatic prehydrolysis step and a subsequent simultaneous saccharification and fermentation (SSF) step with a xylose-fermenting strain of Saccharomyces cerevisiae. A successful

Midterm results of the Ross procedure in children : An appraisal of the subannular implantation with interrupted sutures technique

OBJECTIVES: The support of the pulmonary autograft root by the fibromuscular left ventricular outflow tract is emphasized to address the concern related to the dilatation of the pulmonary autograft structures in the paediatric population. METHODS: This retrospective study analyses the outcomes of 75 children who were operated between 1998 and 2012 with the subannular interrupted sutures technique

Can System Truncation Speed up Ligand-Binding Calculations with Periodic Free-Energy Simulations?

We have investigated whether alchemical free-energy perturbation calculations of relative binding energies can be sped up by simulating a truncated protein. Previous studies with spherical nonperiodic systems showed that the number of simulated atoms could be reduced by a factor of 26 without affecting the calculated binding free energies by more than 0.5 kJ/mol on average (Genheden, S.; Ryde, U.

Rosiglitazone reduces office and diastolic ambulatory blood pressure following 1-year treatment in non-diabetic subjects with insulin resistance

Objective. Rosiglitazone (RSG) has been reported to reduce blood pressure (BP) in patients with type-2 diabetes, but similar effects in non-diabetic people with insulin resistance is less clear. Our aim was to test the long-term BP-lowering effects of RSG compared with placebo. Methods. We recruited participants for BP evaluation of RSG treatment from a larger intervention trial. Office BP was rec

How does sampling methodology influence molecular detection and isolation success in influenza a virus field studies?

Wild waterfowl are important reservoir hosts for influenza A virus (IAV) and a potential source of spillover infections in other hosts, including poultry and swine. The emergence of highly pathogenic avian influenza (HPAI) viruses, such as H5N1 and H5N8, and subsequent spread along migratory flyways prompted the initiation of several programs in Europe, North America, and Africa to monitor circula

Late mortality and morbidity among long-term leukemia survivors with Down syndrome : A nationwide population-based cohort study

Background: Late health consequences of treatment for childhood leukemia are well documented. Although individuals with Down syndrome (DS) have a substantially increased risk of leukemia, information on late effects in this group is almost nonexistent. The aim of this study was to evaluate the mortality and morbidity among 5-year leukemia survivors with DS. Procedure: We compared 5-year leukemia s

Introducing micro-finance in Sweden

The case describes the first year of efforts to introduce microfinance as a tool to work with vulnerable groups in Sweden, more particularly ex-convicts, former drug-addicts and long-term unemployed women of immigrant background. The teaching objective is to discuss whether micro-finance can be seen as a tool to catalyze social change in developed welfare states such as Sweden, or if it rather rei

Direct measurement of fluorescence lifetime using high speed data acquisition

Time-correlated single photon counting (TCSPC) is commonly used to measure the lifetime of fluorescence from dye molecules. In TCSPC, the sample is excited by a pulsed laser and the arrival time of each of the emitted photons at the detector relative to a trigger is recorded. An important criterion of the technique is that the excitation intensity of the laser has to be low enough such that the de

Small Scale Monoclonal Antibody Purification Platform

Småskalig plattform för upprening av monoklonala antikroppar Utvecklingen av en uppreningsplatform för antikroppar visar en 30% ökning i produk-tivitet med hjälp av parallella flödesbanor. Det är nu också möjligt att upprena ännu fler prov per körning än tidigare. Utvecklingen av nya antikroppar blir allt mer viktigare i dagens samhälle för att kunna förbättra vår analytiska och diagnostiska fö

Hemma bra men borta bäst? - Tvångsomhändertagande av barn och intresseavvägningar vid vårdens upphörande

Varje år tvångsomhändertas tusentals barn av socialnämnden och placeras för vård enligt LVU i ett familjehem. Att tvångsvårda ett barn är mycket ingripande, men vad innebär egentligen ett sådant omhändertagande? Vad kan barnets familj göra och vad har socialnämnden för skyldigheter för att möjliggöra ett upphörande av vården? Ställs barnkonventionen mot EKMR i någon del av processen och vad innebäEach year, the social service forcibly places thousands of children for care within LVU in a foster home. To forcibly place a child for care is a very intrusive measure, but what does this placement really mean? What can the child’s family do and what obligations do the social service have for the care to cease? Is the convention on the rights of the child put against ECHR at any moment and what d

Jump Estimation of Hidden Markov Models with Time-Varying Transition Probabilities

En Dold Markovmodell (HMM) kan användas för modellera tidsserier på ett sätt som beskriver olika beteenden under olika perioder; till exempel kan den beskriva finansiella tidsseriers benägenhet att plötsligt ändra riktning då marknadssentimentet förändras, exempelvis på grund av en pandemi. Givet en tidsserie, tänker man sig att den antar olika tillstånd som ej går att observera men som reflekteraThe Hidden Markov model is applicable to a wide variety of fields. Applied to financial time series, its assumed underlying state sequence can reflect the time series' tendency to behave differently over different periods of time. In many situations, models could be improved by including exogenous data. However, that may in some cases be inappropriate in practice as the model could get too mat

The future of Hästbergadammen - Restoration and re-purposing of an abandoned hydroelectric powerplant

This thesis work is an academic study investigating how to transform and re-purpose the abandoned hydroelectric powerplant, Hästbergadammen. The powerplant has been abandoned since the dam collapsed in 2010, and the case of rebuilding it has been in the Land and Environment Court since 2016. The thesis proposes a new purpose for the site. It suggests giving back a public monumental place where t