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An efficient numerical method for nearly simultaneous computation of all conditional moments needed for quasi maximum likelihood estimation of parameters in discretely observed stochastic differential equations is presented. The method is not restricted to any particular dynamics of the stochastic differential equation and is virtually insensitive to the sampling interval. The key contribution is
Intermodality or combining more than one transport mode during a single trip has been put forward to facilitate a modal shift from private car to more environmentally friendly modes such as public transport, cycling or walking. Bike-and-ride – that is, integrating cycling and public transport in one trip – is an attractive combination, as cycling as an active and clean mode is faster than walking
Background: Brief screening instruments focusing on autism spectrum disorder (ASD) that can be administered in primary care are scarce; there is a need for shorter and more precise instruments. The Autism-Tics, AD/HD and other Comorbidities inventory (A-TAC) has previously been validated for ASD reporting excellent validity. This study aims to determine the psychometric properties of each item in
INTRODUCTION: Fetal cardiovascular magnetic resonance (CMR) imaging is used clinically and for research, but has been previously limited due to lack of direct gating methods. A CMR-compatible Doppler ultrasound (DUS) gating device has resolved this. However, the DUS-gating method is not validated against the current reference method for fetal phase-contrast blood flow measurements, metric optimize
Modal choice is a prominent concept within transport studies. However, the term is often used quite loosely, with little known about the factors lying behind the choice, the alternatives available to a person, and whether the person had a ‘choice’ to begin with. This study draws on a travel survey among older people living in Sweden’s large metropolitan regions. The questions posed as part of this
Lean Startup has been impacting how startups and incumbents innovate their business models. However, academic understanding of Lean Startup and the associated experimentation process is only emerging. Recent academic critique of Lean Startup by Felin and colleagues (in press) highlights the inadequate guidance provided for hypotheses generation; limits of experiential learning from customer feedba
In the present paper, linear substructures with nonlinearities localized at their interfaces, such as the joints in a beam structure, are studied. By subdivision of the total structure into substructures, reduced subsystems are obtained by component mode synthesis. Nonlinear elements are introduced at supports or between substructures. A numerical example is presented where a beam subjected to bla
Deficiency of ornithine-δ-aminotransferase (OAT) in humans results in gyrate atrophy. Early diagnosis may allow initiation of treatment before irreversible damage has occurred. However, diagnosis is commonly delayed well into adulthood because of the nonspecific character of initial symptoms. Here, we report findings in a neonate who was evaluated because of a positive family history of OAT defici
Event-based sampling has been proposed as a general technique for lowering the average communication rate, energy consumption and computational burden in remote state estimation. However, the design of the event trigger is critical for good performance. In this paper, we study the combination of innovation-based triggering and state estimation of nonlinear dynamical systems using the particle filt
Background: OncoMasTR is a new multigene prognostic test that was discovered via a novel transcriptional network analysis method that identified upstream Master Transcription Regulators (MTRs), which regulate previously identified prognostic biomarkers. The optimised OncoMasTR signature incorporating clinicopathological information has been shown to be significantly prognostic for predicting dista
Vehicle-to-vehicle (V2V) wireless communications can improve traffic safety at road intersections and enable congestion avoidance. However, detailed knowledge about the wireless propagation channel is needed for the development and realistic assessment of V2V communication systems. We present a novel geometry-based stochastic MIMO channel model with support for frequencies in the band of 5.2-6.2 G
Running-in process of low metallic brake pads and cast iron discs are investigated using full scale inertia brake dynamometer designed for particle emission studies. The airborne particles are measured using ELPI+ and collected on filters. The pads and disc contact surfaces are studied using microscopy techniques. It is observed that the particle emissions from the new pads and discs are significa
This report describes the methodology for performing a quantitative risk analysis for a unidirectional road tunnel. By using representative accident scenarios, a basic queue model and performing an evacuation analysis the amount of casualties for each scenario can be estimated. By using the described methodology it gives the decision-makers a good idea of the risk level in the tunnel. The results
Due to the multiple benefits of biogas systems, the Chinese Government has made great efforts to promote the development of biogas systems in rural China, especially household biogas plants and medium and large scale biogas plants to treat manure and waste water from intensive livestock and poultry farms. This thesis conducts a comprehensive literature review to understand the current situation of
Nynas Petroleum is one of the world´s largest producers of naphthenic specialty oils. They have refineries in several parts of the world and their largest production facility is situated in Nynäshamn, Sweden. They also have oil depots in all continents and their largest depot is located in Antwerp, Belgium. In the beginning of 2007 Nynas introduced a new type of transformer oils, called Nova grade
