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Background: Breast cancer (BC) and related treatment are associated with the risk of developing a wide range of persistent disabling impairments. Despite extensive research in the field and an enhanced focus on BC rehabilitation, up to 34-43% of these patients are at risk of developing chronic distress. In addition, it is known that these patients repeatedly report unmet needs, which are strongly

Satelliten Gaia har samlat data för ESA sedan den skjöts upp år 2013. Denna data har gett astronomer en ny inblick i hur den galaktiska miljön ser ut i vår närhet. Gaia har varit ett så lyckat projekt att man nu har börjat arbeta med en uppföljare till Gaiasatteliten, GaiaNIR, som står för Gaia Near InfraRed. Planen är att GaiaNIR ska observera i det infraröda spektrumet, något som gör att extinktGaia Near InfraRed, or GaiaNIR for short, is a proposed successor to the original Gaia satellite. Its main improvement over the Gaia satellite is the fact that GaiaNIR will observe in the infrared spectrum. This would allow the telescope to see through the heavy extinction of the Milky Way, as the interstellar gas and dust obstructs light mainly in the visible spectrum. A selection function utiliz

Background and Aims. While the rationale for coronavirus disease 2019 (COVID-19) vaccination is to reduce complications and overall mortality, some cardiovascular complications from the vaccine itself have been demonstrated. Myocarditis and pericarditis are recognized as rare acute adverse events after mRNA vaccines in young males, while evidence regarding other cardiovascular events remains limit

The International Monetary Fund (IMF) is a highly influential financial international organization that will be vital for the success of the Sustainable Development Goals (SDGs). While the IMF has been criticized by civil society actors for its negative impact on sustainable development, it is now focusing on supporting the SDGs. This support is particularly relevant when it comes to ensuring the

Accountability is central for accelerating progress towards achieving the Sustainable Development Goals (SDGs). It means to hold powerful actors answerable for how they turn agreements into action. Governments, who hold the main responsibility for SDG implementation, can in the ideal case be held accountable by voters, parliaments, civil society, and the media, for how they address the SDGs. At th

This study introduces a novel approach for synthesising a surface-imprinted polymer-ordered mesoporous silica adsorbent, known as SiO2@MIPs-CAPcr, with high selectivity for chloramphenicol (CAP) adsorption by employing an activator that was regenerated by electron atom transfer radical polymerisation (ARGET ATRP). Optimal synthesising conditions for SiO2@MIPs-CAPcr have been determined, including

Fastställande av faderskap har historiskt haft stor betydelse i Sverige och varit avgörande för barns rättsliga och sociala ställning. Under lång tid gjordes en tydlig åtskillnad mellan barn födda inom och utom äktenskap, där barn utom äktenskap hade begränsade rättigheter. Sexuella relationer utom äktenskap var länge kriminaliserade och det kvarlevande stigmat kom även att prägla lagstiftningen oThe establishment of paternity has historically been of great significance in Sweden and has been decisive for children’s legal and social status. For a long time, a clear distinction was made between children born within and outside of marriage, where children born outside of marriage had limited rights. Sexual relations outside of marriage were long criminalized, and the lingering stigma also ca

Organic pollutants in aquatic environments pose a threat to ecosystems and human health, a challenge that requires urgent resolution. This urgent threat highlights the need for the development of efficient technologies for pollutant detection and degradation in environmental protection. This study presents the successful fabrication of a composite nanomaterial consisting of Ag nanoparticle-decorat

Det är vedertaget i svensk rätt att avtal om framtida överlåtelse av fast egen- dom, såsom optionsavtal, är ogiltiga. En option är en rätt, men inte skyldighet, att i framtiden köpa eller sälja viss egendom. Även om det inte framgår explicit i lagtext eller förarbeten föreligger alltså i praktiken ett förbud mot option till fast egendom. Uppsatsens syfte är att granska huruvida det föreligger skälAgreements concerning future real estate transactions, such as option agree- ments, are invalid in the Swedish legal system. An option constitutes a right, but not an obligation, to buy or sell certain property in the future. There is a prohibition against option agreements to real estate, although it does not appear explicitly in the text of a law or the legislative history. The purpose of this t

Scientific breakthroughs in the field of cell and gene therapy lay the groundwork for therapeutic innovation, but their translation and integration into routine care is delayed by systemic inefficiencies and limited cross-sector alignment. The Advanced Therapies model of Lund is a proactive and integrated approach designed to accelerate the development of advanced therapies from discovery to reimb

Introduction: It is well known that urinary tract infection (UTI) during pregnancy is associated with preterm birth, but information about the risk of preterm birth depending on gestational week of infection is sparingly described in the literature. Material and Methods: An observational study based on data from Swedish registers including women giving birth 2014–2020 (n = 684 595). Pregnant women

This paper provides an update on the fast-evolving topic of the induced polarization (IP) method applied to biogeophysics. It emphasizes new understandings of the IP phenomena associated with biological activity, pointing out new developments and applications, and identifying existing knowledge gaps. The focus is on the use of IP as related to living organisms, including micro-organisms and plants

Bacteria encode diverse defence systems, including restriction-modification and CRISPR-Cas, that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstrate that many recently identified antiphage defence operons comprise a nuclease and NTPase protein, suggesting that additional nucleic acid-targeting systems remain to be understood. Here we develop large-scale compa

Long RSH enzymes, Rel and RelA, are master regulators of bacterial (p)ppGpp alarmones levels. Bifunctional Rel transitions between a compact hydrolysis-competent (HD ON) state, a relaxed catalytically inactive (HD OFF/SYNTH OFF) state, and an elongated synthesis-competent (SYNTH ON) state, whereas RelA samples only the latter two. The distribution of these states is controlled by starved ribosomes

Premise of research. Selfing rates in mixed-mating plant species are often found to fluctuate greatly across time and space. Environmentally induced changes in floral traits may mediate changes in selfing rates through several mechanisms, including direct effects via changes in traits influencing autofertility rates and indirect effects via changes in traits affecting the rate of pollinator visita

This explorative study investigates the emergence of gray zone markets from search engines amidst the global expansion of online markets. With the analytical approach of infrastructural inversion, we examine how the search infrastructure constructs access to a gray zone market including both authorized online pharmacies and unauthorized vendors. Using Sweden and Google Search as a case, we explore

Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR