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Development of the ClinESSDAI : A clinical score without biological domain. A tool for biological studies

Objective To develop and validate ClinESSDAI (Clinical European League Against Rheumatism Sjögren's Syndrome Disease Activity Index), ie, ESSDAI without the biological domain. Patients and methods The 702 fictive vignettes derived from 96 real cases of primary Sjögren's syndrome of the ESSDAI development study were used. As for ESSDAI development, the physician assessment of disease activity (0-10

Solar assisted pervaporation (SAP) for preserving and utilizing fruits in developing countries

The purpose of this work is to develop and implement a simple and robust preservation technology that can enhance food and economic security and thereby improve the lives of people in developing countries. The technique under development is termed “solar assisted pervaporation (SAP)”. It is a sustainable technology whereby fruit juices or purées are concentrated using reusable pouches made of “bre

Sexköpsförbuden i Norden – (o)lika regleringar En rättspolitisk analys med fokus på skyddsvärden

Uppsatsen syftar till att utreda de kriminalpolitiska skälen bakom de nordiska sexköpslagstiftningarna och gör detta utifrån att besvara vad motiven bakom de olika lagarna är samt vilka skyddsvärden de olika lagarna skyddar. De olika lagarnas resultat i form av gällande rätt men även deras förarbeten och skyddsvärden jämförs och analyseras. Även Danmark diskuteras trots att de saknar ett sexköpsföThe purpose of this essay is to investigate the criminal policy beneath the Nordic countries’ sex purchase bans and does so by answering what the motives are for the different bans and also which the protective values are for the laws. The current prohibitions, but also their preliminary works and protective values are analyzed and compared. The case of Denmark is also discussed even though they l

Stochastic Event-Based Control and Estimation

Digital controllers are traditionally implemented using periodic sampling, computation, and actuation events. As more control systems are implemented to share limited network and CPU bandwidth with other tasks, it is becoming increasingly attractive to use some form of event-based control instead, where precious events are used only when needed. Forms of event-based control have been used in prac

Decision-Analytic Models: Current Methodological Challenges

Modelers seeking to help inform decisions about insurance (public or private) coverage of the cost of pharmaceuticals or other health care interventions face various methodological challenges. In this review, which is not meant to be comprehensive, we cover those that in our experience are most vexing. The biggest challenge is getting decision makers to trust the model. This is a major problem bec

Low-Molecular Weight Inhibitors of Galectins

The galectins are known to be able to recognize and cross-link beta-D-galactopyranoside-containing glycoconjugates as a result of presenting multiple binding sites. This review summarizes efforts in our group for the last ten years towards low-molecular weight chemically modified carbohydrate derivatives. In addition to providing an avenue for improved affinity and galectin-selectivity, we have fo

Architecture of the global land acquisition system: applying the tools of network science to identify key vulnerabilities

Global land acquisitions, often dubbed 'land grabbing' are increasingly becoming drivers of land change. We use the tools of network science to describe the connectivity of the global acquisition system. We find that 126 countries participate in this form of global land trade. Importers are concentrated in the Global North, the emerging economies of Asia, and the Middle East, while exporters are c

The Shortcut Index

With a novel path index design, called the Shortcut Index, we partially solve the problem of executing traversal queries on dense neighborhoods in a graph database. We implement our design on top of the graph database Neo4j but it could be used for any graph database that uses the labeled property graph model. By using a B+ tree, the Shortcut Index can achieve what we call neighborhood locality a

Skada i följd av trafik/Skade som motorvogn gjer – en jämförande analys

Denna uppsats analyserar och jämför legal reglering av motorfordons ansvar vid uppkommen skada i Sverige och Norge, med fokus på rekvisiten ”skada i följd av trafik” i Sverige respektive skade som motorvogn gjer i Norge. Dessa rekvisit är de som definierar omfånget av fordons ansvar vid uppkommen skada och därmed de skador som ska ersättas av fordonets trafikförsäkring. Uppsatsen visar att syftThis essay analyzes and compares the legal regulation of motor liability insurance in Sweden and Norway with emphasis on the primary legal requirements for the Laws to apply, namely “skada till följd av trafik” (damage as a result of motor vehicle traffic) in Sweden and “skade som motorvogn gjer” (damage caused by motor vehicle) in Norway. These are the primary requirements that define the scope

Does a long-term oscillation in nitrogen concentration reflect climate impact on submerged vegetation and vulnerability to state shifts in a shallow lake?

Various ecosystems, including shallow lakes, are suggested to possess alternative stable state dynamics. The response of such systems to environmental change is non-linear and not fully reversible, which calls for identification of feedback mechanisms and subtle changes connected to structural stability. Here, we used a 25-year data series on water chemistry to make inferences on processes prior t

From Trade Preferences to Trade Facilitation

Popular Abstract in Swedish Populärvetenskaplig sammanfattning: Det genomgående temat i avhandlingen är hur handeln mellan den Europeiska Unionen (EU) och utvecklingsländer kan öka. Två olika policyalternativ utvärderas: så kallade handelspreferenser samt förenklingar av handelsprocedurer. Handelspreferenser innebär i sin enklaste form att höginkomstländer kräver lägre tullar på importvaror somThe main theme of the thesis is how to increase trade between the European Union (EU) and developing countries. Two available policy options are assessed: trade preferences and trade facilitation. Chapter 1 offers a broad discussion of these policies, and concludes that while trade preferences, which once dominated North-South trade relations, are at a risk of becoming obsolete, trade facilitation

Design and Development of a Multifunctional Test Rig

In this project, the several steps in a product development process can be followed, from the first brainstorming of basic concepts to the final implementation of the manufactured product in the factory. The project was assigned by Faiveley Transport Nordic AB and its aim was to design a well functioning test rig for testing of their train brake units. The new rig’s advantages compared to old exi

The Compatibility of Limitation on Benefits Provisions in Tax Treaties with EC Law

Most bilateral tax treaties contain provisions with the objective of preventing different types of treaty abuse. Limitation on benefits clauses are an example of such provisions, and are generally found in United States tax treaties. These include various tests, which need to be fulfilled by a taxpayer wishing to enjoy the benefits of a tax treaty. Most of the United States tax treaties with EU Me

Modelling and analysis of multi-scale networks

The broad goal of this thesis is to develop a deeper mathematical understanding of the processes at work in the neuronal network of a brain by rigorously examining very fundamental elements of the processes involved. Paper I considers the flow of discrete signals on a graph and Paper II the complexity arising from the interplay of simple units. The concrete probabilistic investigations of such mod

Design and Control of Long-Pulse High-Power Klystron Modulators

The European Spallation Source (ESS) is an under-construction material science research facility in Lund, Sweden, and will upon completion host the most powerful superconducting linear accelerator (linac) in the world. The ESS linac is powered by klystron modulators required to deliver long high-power pulses (pulse amplitude 115 kV/100 A, pulse length 3.5 ms, pulse repetition rate 14 Hz) of very h