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Determination of 3′-phosphoadenosine-5′-phosphosulfate in cells and Golgi fractions using hydrophilic interaction liquid chromatography–mass spectrometry

3′-Phosphoadenosine-5′-phosphosulfate (PAPS) is a key player in the sulfation of biomolecules, but methods for selective measurements are lacking. A liquid chromatography–mass spectrometry (LC–MS) approach for measuring PAPS was developed. A central feature of the method was employing hydrophilic interaction liquid chromatography (HILIC), which is highly suited for separating very polar/charged co

Reversible size of shear-induced multi-lamellar vesicles

We have investigated the reversibility in the shear-induced multi-lamellar vesicle (MLV) size during stepwise cycling of the shear rate by employing common rheometry, polarized light microscopy and rheo-optic techniques. We thus address the question whether there is a true MLV steady state, irrespective of history. The system studied, was the nonionic surfactant triethylene glycol decyl ether (C10

Low-Molecular Weight Inhibitors of Galectins

The galectins are known to be able to recognize and cross-link beta-D-galactopyranoside-containing glycoconjugates as a result of presenting multiple binding sites. This review summarizes efforts in our group for the last ten years towards low-molecular weight chemically modified carbohydrate derivatives. In addition to providing an avenue for improved affinity and galectin-selectivity, we have fo

Early increase in serum-COMP is associated with joint damage progression over the first five years in patients with rheumatoid arthritis

Background: Currently available biomarkers for the early tissue process leading to joint damage in rheumatoid arthritis are insufficient and lack prognostic accuracy, possibly a result of variable activity of the disease over time. This study represents a novel approach to detect an altered activity of the disease process detected as increasing serum-COMP levels over a short time and whether this

The Global War On Terrorism as Meta-Narrative: An Alternative Reading of Recent Chinese History

When we speak of the “Cultural Revolution” in China, we actually refer not to the past but to a narrative interpretation of the past, a particular organization of knowledge which has gone unquestioned for a long time. This paper attempts to develop an alternative narrative scope from which to view the final ten-plus years of politics in the People’s Republic under Mao Zedong. It looks at that same

Influence of the Electron-Cation Interaction on Electron Mobility in Dye-Sensitized ZnO and TiO2 Nanocrystals: A Study Using Ultrafast Terahertz Spectroscopy

Charge transport and recombination in nanostructured semiconductors are poorly understood key processes in dye-sensitized solar cells. We have employed time-resolved spectroscopies in the terahertz and visible spectral regions supplemented with Monte Carlo simulations to obtain unique information on these processes. Our results show that charge transport in the active solar cell material can be ve

Improved Key Recovery Attack on the BEAN Stream Cipher

BEAN is a newly proposed lightweight stream cipher adopting Fibonacci FCSRs. It is designed for very constrained environments and aims at providing a balance between security, efficiency and cost. A weakness in BEAN was first found by Ågren and Hell in 2011, resulting in a key recovery attack slightly better than brute force. In this paper, we present new correlations between state and keystream w

Risk of thromboembolic diseases in men with prostate cancer: results from the population-based PCBaSe Sweden

Background Cancer is associated with an increased risk of thromboembolic diseases, but data on the association between prostate cancer and thromboembolic diseases are scarce. We investigated the risk of thromboembolic disease in men with prostate cancer who were receiving endocrine treatment, curative treatment, or surveillance. Methods We analysed data from PCBaSe Sweden, a database based on the

A model for the development of Aedes (Stegomyia) aegypti as a function of the available food

We discuss the preimaginal development of the mosquito Aedes aegypti from the point of view of the statistics of developmental times and the final body-size of the pupae and adults. We begin the discussion studying existing models in relation to published data for the mosquito. The data suggest a developmental process that is described by exponentially distributed random times. The existing data s

Modelling of mineral dust for interglacial and glacial climate conditions with a focus on Antarctica

The mineral dust cycle responds to climate variations and plays an important role in the climate system by affecting the radiative balance of the atmosphere and modifying biogeochemistry. Polar ice cores provide unique information about deposition of aeolian dust particles transported over long distances. These cores are a palaeoclimate proxy archive of climate variability thousands of years ago.

Headache in Systemic Lupus Erythematosus Results From a Prospective, International Inception Cohort Study

ObjectiveTo examine the frequency and characteristics of headaches and their association with global disease activity and health-related quality of life (HRQOL) in patients with systemic lupus erythematosus (SLE). MethodsA disease inception cohort was assessed annually for headache (5 types) and 18 other neuropsychiatric (NP) events. Global disease activity scores (SLE Disease Activity Index 2000

Critical evaluation of factors affecting chloride initiated reinforcement corrosion in concrete

This licentiate study has been completed as a part of a larger experimental program "Durability of Reinforced Concrete Structures in Marine Environment" carried out in Sweden and Denmark. The aim of this work has been to identify and critically evaluate some major parameters influencing the onset of active reinforcement corrosion in concrete in marine environment. Since the topic is naturally very

Vesicular-arbuscular mycorrizae for dating multiple paleosols and carbon loss rate determination

A promising technique for dating paleosols is reported based on radiocarbon (C-14) dating of asexual spores from vesicular-arbuscular mycorrizae (VAM). The soils are dispersed in water and some 6000-8000 spores separated by hand picking under a low power microscope. The dried spores are then dated by accelerator mass spectroscopy (AMS). A chronosequense of closely superimposed paleosols from an ar

Quadrupole moments of wobbling excitations in Lu-163

Lifetimes of states in the triaxial strongly deformed bands of Lu-163 have been measured with the Gammasphere spectrometer using the Doppler-shift attenuation method. The bands have been interpreted as wobbling-phonon excitations from the characteristic electromagnetic properties of the transitions connecting the bands. Quadrupole moments are extracted for the zero-phonon yrast band and, for the f

HCCI Combustion Phasing with Closed-Loop Combustion Control Using Variable Compression Ratio in a Multi-Cylinder Engine

This study applies Closed-Loop Combustion Control (CLCC) using Variable Compression Ratio (VCR) and cylinder balancing using variable lambda to solve the problem. Step changes of set points for combustion phasing, Compression Ratio (CR), and load together with ramps of engine speed and inlet air temperature are investigated. Performances of the controllers are investigated by running the engine at

Capital Shares and Income Inequality: Evidence from the Long Run

This paper investigates the relationship between the capital share in national income and personal income inequality over the long run. Using a new historical cross-country database on capital shares in 19 countries and data from the World Wealth and Income Database, we find strong long-run links between the aggregate role of capital in the economy and the size distribution of income. Over time, t

NMR Studies of Gel-Emulsions; Diffusometry and Applications of Novel Field Gradient Techniques

Popular Abstract in Swedish Avsikten med detta arbetet har varit att utveckla kärnmagnetisk resonans, NMR, tekniken, applicerat på gel-emulsioner. Gel-emulsioner är viktiga i många tekniska formuleringar så som i livsmedel, i kosmetika, i läkemedelsformuleringar och i sprängmedel för att nämna några applikationer. Vi har arbetat med en teknik som kallas NMR diffusometri, som utvecklats av StejskalThe aim of these studies has been to investigate what information that can be obtained on gel-emulsions with nuclear magnetic resonance, NMR, as the investigating tool. The gel-emulsions are important in many technical applications such as in food products, in cosmetic and pharmaceutical formulations, and in emulsion explosives, just to name a few applications. We have worked with the NMR diffusom