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There is a growing scientific consensus that limiting the increase in global average temperature to around 2 C above pre-industrial levels is necessary to avoid unacceptable impact on the climate system. This requires that the developed countries' emissions are radically reduced during the next 40 years. Energy scenario studies provide insights on the societal transitions that might be implied by
Rheumatoid arthritis (RA) is a highly disabling disease affecting all structures of the joint. Understanding the pathology behind the development of RA is essential for developing targeted therapeutic strategies as well as for developing novel markers to predict disease onset. Several molecules normally hidden within the cartilage tissue are exposed to complement components in the synovial fluid u
A concept for time-sensitive optical detectors is described that shows how to confirm whether the detection device is operating in the linear response regime. By evaluating the recorded time decay of a thermographic phosphor, even weak saturation effects far from obvious situations can be identified and further related to either optical or electrical saturation. The concept has been validated by r
A means for noninvasive measurement of transverse and longitudinal characteristics of bunched beams in synchrotrons has been developed based on high sensitivity slotted waveguide pickups. The pickups allow for bandwidths exceeding hundreds of MHz while maintaining good beam sensitivity characteristics. Wide bandwidth is essential to allow bunch-by-bunch measurements by means of a fast gate. The Sc
Background: Proteins can be used in drug delivery systems to improve pharmacological properties of an active substance. Differences in pH between tissues can be utilized in order to achieve a targeted drug release at a specific location or tissue, such as a tumor. The enamel matrix protein amelogenin has a pH dependent solubility profile and self-assemble to form aggregates at neutral pH. This cou
Background: Critical needs for treatment trials in gastroesophageal reflux disease (GERD) include assessing response to treatment, evaluating symptom severity, and translation of symptom questionnaires into multiple languages. We evaluated the previously validated Reflux Disease Questionnaire (RDQ) for internal consistency, reliability, responsiveness to change during treatment and the concordance
Stable isotope analysis provides a powerful tool for describing the energetic pathways in a variety of ecosystems. However, isotope ratios of animal tissues can be altered by preservation methods, potentially leading to biased estimates of energy pathways when they are not taken into account. Here, we investigated the direct preservation effects of formalin, ethanol, NaCl, and drying on the delta
To test the hypothesis that dissolved organic nitrogen (DON) is important for sustaining primary production by the microphytobenthos (MPB) in nitrogen-limited conditions, we measured the uptake of (15)N-labelled urea, the amino acids glycine (GLY) and glutamic acid (GLU), and nitrate and ammonium under simulated in situ light and temperature conditions. Microphytobenthic primary production and chl
Background: Animal experimental studies and previous randomized trials suggest an improvement in mortality and neurological function with temperature regulation to hypothermia after cardiac arrest. According to a systematic review, previous trials were small, had a risk of bias, evaluated select populations, and did not treat hyperthermia in the control groups. The optimal target temperature manag
We consider steady symmetric gravity water waves on finite depth with constant vorticity and a monotone surface profile between crests and troughs. The problem is transformed into one concerning the vertical velocity. A representation formula for the stream function in terms of the surface and the vorticity is presented, and we show that the surface can be determined from the vertical velocity.
In this article an operator theoretic interpretation of the generalized Titchmarsh-Weyl coefficient for the Hydrogen atom differential expression is given. As a consequence we obtain a new expansion theorem in terms of singular generalized eigenfunctions.
We consider the effect of signaling rate (baud rate) on the information rate of single carrier linear transmission systems with Gaussian inputs. Several different communication scenarios are investigated: correlated or uncorrelated symbols, a fixed modulation pulse or a modulation pulse varying with the signaling rate and frequency selective or flat channels. For uncorrelated symbols, we show that
The model for permanent deformation in asphalt concrete (AC) layers used in the Mechanistic-Empirical Pavement Design Guide (MEPDG) was evaluated. Two instrumented flexible pavements were subjected to heavy vehicle simulator testing at three constant temperatures. Permanent deformation modelling was carried out using the MEPDG software v1.003 at the highest accuracy level. The nationally calibrate
Pickering emulsions are emulsions that are stabilized by fine particles. They have been the focus of considerable research in the past decade due to their properties such as high stability with respect to coalescence and Ostwald ripening, as well as due to advances in nanotechnology that allows us to create and characterize nano-scale structures in new ways. This work reviews some of the recent wo
In the Swedish context Swedish language skills are considered to be a crucial factor for an individual's ability to establish him/herself in society as well as on the labour market. Despite this, the Swedish organisation Swedish for Immigrants (SFI) has been exposed to extensive critique: Not enough students manage to establish themselves on the labour market, but get trapped in SFI. The purpo
HR indicators are increasingly used as a method for analysis in the work with human rights. However, the concept of HR indicators is often subject to confusion due to the lack of a common and universal theoretical framework. This study focuses on the elaboration of HR indicators for state reporting within the UN treaty monitoring bodies and argues that an extended and more coherent use of HR indic
In 1991 the African Union established a plan for creating a monetary union for the whole continent. The plan, the Abuja Treaty, aim to unify the continent, creating stability and improving economic welfare. Several regional economic communities (RECs) are the foundation of this plan which means that the progress is primary dependent on their successful development. This essay studies Africa’s prog
