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Background About 30% of cases of chronic lymphocytic leukaemia (CLL) carry quasi-identical B-cell receptor immunoglobulins and can be assigned to distinct stereotyped subsets. Although preliminary evidence suggests that B-cell receptor immunoglobulin stereotypy is relevant from a clinical viewpoint, this aspect has never been explored in a systematic manner or in a cohort of adequate size that wou

Purpose: To characterize the clinical phenotype regarding retinal function and macular appearance in patients with spinocerebellar ataxia type 7 (SCA 7), with an emphasis on electrophysiological findings. Methods: Three patients from two Swedish families were given an ophthalmological examination including visual acuity, fundus inspection, Farnsworth's color vision test, Goldmann perimetry, full-f

Christian Zionism is usually characterized as a theological and political movement grounded in literalist bible hermeneutics and End-time speculations that dedicate unwavering support to the State of Israel and the Jewish people. The prophetic element in Christian Zionism has in later years been downplayed for a more down-to-earth focus on social and political commitment to the well-being of the s

A departing assumption in my work is the idea about a particular kind of conflict inherent in the theatrical line, produced by its situatedness in the specific relational doubt created in the speaking, performing voice and body, a space articulated already in the written line, as writing intended to be spoken. To the inherent self-contradiction in such utterances are added the layers of conscious

Today, 14 years have gone since the whole world turned their backs on Rwanda, the small country in East Africa, during a time when its population needed us the most. These were the same nations that already after the Second World War had made a promise about ''Never Again'', then meaning that they would never again allow another attempt to exterminate an entire ethnic group. It was

The importance of the alluring goal of having the “perfect” or “true” information is more than visible in the financial world. In portfolio management financial correlation matrices measure the unsystematic correlations between assets e.g. stocks. Finding the true correlations between stocks would enable the creation of portfolios with less risk. In reality this information is more than hard to co

This is a study on the young client's encounter 1 with the welfare system which main goal is the transition to work or study. The focus is on the clients experiences of this encounters and if they consider social allowance as a mean of lasting support. The method of data collection has been interviewing five people, two females and three males, all about the age of 20. All five had for some ti

RATIONALE: The alveolar pathology in chronic obstructive pulmonary disease (COPD) involves antigen-driven immune events. However, the induction sites of alveolar adaptive immune responses have remained poorly investigated. OBJECTIVES: To explore the hypothesis that interfaces between the alveolar lumen and lymphoid aggregates (LAs) provide a structural basis for increased alveolar antigen uptake i

The aim of the present study was to test the hypothesis that a prolonged refeeding duration after successful very-low-energy diet (VLED)-induced weight loss beneficially affects weight development and eating behaviour. Patients (it 269) were recruited to a I-year obesity treatment programme with 12 weeks of an initial VLED. After the VLED, patients with 10 % weight loss were randomly allocated to

Instabilities in planetary systems can result in the ejection of planets from their host system, resulting in free-floating planets (FFPs). If this occurs in a star cluster, the FFP may remain bound to the star cluster for some time and interact with the other cluster members until it is ejected. Here, we use N-body simulations to characterize close star-planet and planet-planet encounters and the

Aims/hypothesis Islet autoantibodies, in addition to elevated blood glucose, define type 1 diabetes. These autoantibodies are detectable for a variable period of time before diabetes onset. Thus, the occurrence of islet autoantibodies is associated with the beginning of the disease process. The age at, and order in, which autoantibodies appear may be associated with different genetic backgrounds o

Organometal halide perovskites have attracted tremendous attention for optoelectronic applications. Charge carrier trapping is one of the dominant processes often deteriorating the performance of devices. Here, we investigate the details of trap behavior in colloidal nanoparticles (NPs) of CH3NH3PbBr3 perovskites with mean size of 8 nm and the corresponding bulk crystals (BCs). We use excitation i

Objective To evaluate the psychometric properties of the Fatigue Severity Scale (FSS), the Fatigue Impact Scale (FIS), and the Multidimensional Fatigue Inventory (MFI-20) in persons with late effects of polio (LEoP). More specifically, we explored the data completeness, scaling assumptions, targeting, reliability, and convergent validity. Methods A postal survey including FSS, FIS, and MFI-20 was

The Kurdish economy is today heavily dependent on hydrocarbons exports. Current trends are that hydrocarbons exporting and processing countries, as well as interest groups within these countries, are pushing to expand production and maximise profits while this is still possible. The magnitude and observed acceleration of the present climate emergency - with major impacts both in terms of loss of c

Background: Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are rare diseases with a gradual decline in physical health. Adherence to treatment is crucial in these very symptomatic and life threatening diseases. Objective: To describe PAH and CTEPH patients experience of their self-reported medication adherence, beliefs about medicines and informatio

Here we report an EPR signal that is induced by a pH jump to alkaline pH in the S3 state of the oxygen-evolving complex in photosystem II. The S3 state is first formed with two flashes at pH 6. Thereafter, the pH is changed in the dark prior to freezing of the sample. The EPR signal is 90-100 G wide and centered around g = 2. The signal is reversibly induced with a pK = 8.5 ± 0.3 and is very stabl