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Technical evaluation of a laser-based optical surface scanning system for prospective and retrospective breathing adapted computed tomography.

Background. For breathing adapted radiotherapy, the same motion monitoring system can be used for imaging and triggering of the accelerator. Purpose. To evaluate a new technique for prospective gated computed tomography (CT) and four-dimensional CT (4DCT) using a laser based surface scanning system (Sentinel(™), C-RAD, Uppsala, Sweden). The system was compared to the AZ-733V respiratory gating sys

Functional properties of the four Atlantic salmon (Salmo salar) aryl hydrocarbon receptor type 2 (AHR2) isoforms.

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor through which organochlorine contaminants including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and some polycyclic aromatic hydrocarbons induce toxicity and altered gene expression. Atlantic salmon has multiple AHR genes, of which two belong to the AHR1 clade and four belong to the AHR2 clade. The four AHR2 forms (alph

Within-canopy sesquiterpene ozonolysis in Amazonia

Through rapid reactions with ozone, which can initiate the formation of secondary organic aerosols, the emission of sesquiterpenes from vegetation in Amazonia may have significant impacts on tropospheric chemistry and climate. Little is known, however, about sesquiterpene emissions, transport, and chemistry within plant canopies owing to analytical difficulties stemming from very low ambient conce

Optimizing the Protein Expression of the Cancer Associated Nucleosome Remodeling and Deacetylase Complex: a Study Investigating Both Mammalian and Insect Cells

Hur ser vår inre NuRD ut? NuRD är ett molekylkomplex som arbetar med att slå på och av gener i vårt DNA. Man har upptäckt att NuRD ibland stänger av gener som normalt verkar för att hämma cancer. Om man kunde ta reda på den exakta strukturen av NuRD så skulle man kunna designa läkemedel som hindrar NuRD från att stänga av våra naturliga cancerhämmare. Vår arvsmassa är samlad som en kod i en värThe Nucleosome Remodeling and Deacetylase (NuRD) complex is a transcriptional regulator essential to several normal developmental processes, but also found to have a role in several types of cancer. In order to design cancer therapies targeting this complex, determining the structure and subunit composition is crucial. X-ray crystallography is required for the level of detail desired, demanding la

Personligt betalningsansvar för aktieägare? - En undersökning om ansvarsgenombrott

Ansvarsgenombrott, det vill säga när aktieägare åläggs personligt betalningsansvar för bolagets skulder utan lagstöd, behandlas ingående i denna uppsats. Uppsatsens syfte är att, genom en rättsdogmatisk metod, utreda ansvarsgenombrott som rättsligt institut. Ansvarsgenombrott är ett undantag från huvudprincipen om frihet från personligt ansvar som stadgas i 1 kap. 3§ ABL. Huvudprincipen är ett av This essay investigates ”Piercing the corporate veil”, in other words when the duties of a corporation through a legal decision is treated as a liability of its shareholders. The purpose of the essay is to analyse piercing the corporate veil as a legal institute through a legal dogmatic method. Piercing the corporate veil is an exception from the main principle of shareholders’ limited liability,

Climate governance by experiment? Exploring local climate initiatives through transition theory

Går det att stoppa den globala uppvärmningen genom lokala klimatexperiment? För att begränsa den globala uppvärmningen måste industriländerna till 2050 minska utsläppen med 80-95 %. En sådan omställning är en enorm utmaning, men forskning visar att den är möjlig att genomföra genom nytänkande samhällsstyrning som involverar samhällets samtliga aktörer. Ett nytt spännande sätt att tackla det globaThe response to climate change in cities has proliferated over the last few decades, and progressive climate action at the local level is now ubiquitous. More specifically, local climate action often comes in the shape of ‘climate change experiments’, radical innovations at the local level designed to respond to the imperatives of mitigating and adapting to climate change in the city. This thesis

Mäns konst och menskonst - feministiskt formspråk i en konsthistorisk kontext

The main aim of this study is to answer the hypothesis that Judy Chicago's 1971 photolithograph "Red Flag", along with her academic career, can be seen as an answer to the new approach to art history and what defines art, that Linda Nochlin calls for in her essay "Why have there been no great women artists?". The analysis of "Red Flag", which depicts a bloodfille

Restriktioner vid häktning i svensk gällande rätt - i ljuset av Europakonventionens artikel 3

För att en häktad person inte ska kunna försvåra brottsutredningen går det att ålägga denne restriktioner avseende möjligheterna till kontakt med omvärlden. Det kan emellertid vara mycket påfrestande att vara häktad med restriktioner. Artikel 3 i Europakonventionen innehåller ett förbud mot tortyr samt mot omänsklig eller förnedrande behandling eller bestraffning. Artikeln kan aktualiseras vid anvIn order to prevent a pre-trial detainee from obstructing the criminal investigation it is possible to impose restrictions on the possibilities of contacting the outside world. However, it can be very challenging to be detained with restrictions. Article 3 of the European Convention on Human Rights, which contains a prohibition of torture and inhuman or degrading treatment or punishment, can be ap

Elektrifiering av vägtrafik - Tre fallstudier i Malmö

Elbilars utveckling går fort framåt och fler väljer att investera i en. Vilka olika laddningstekniker finns det? Hur kommer laddningen av elbilar påverka våra elnät? Kraftdistribution till en elvägssträcka modelleras för att påvisa kapacitetskrav och kostnader. Studien visar även hur hemmaladdning och arbetsplatsladdning kan påverka belastningen i elnätet om reglering uteblir.Sweden’s road traffic is responsible for a great part of the emissions of greenhouse gases in the country. Conventional vehicles, driven by fossil fuels, have low efficiency and emits environmentally destructive particles. Electric vehicles can be the solution! Electric vehicles have no local emissions while driving and the electric motors of today have an efficiency of above 90 %. But there are s

Öresundsidentitet - En studie om regional identitet och identitetsskapande i en transnationell kontext

The Öresund region, or Greater Copenhagen as it also is represented as, is a cross-border region connecting Skåne with Copenhagen. Political initiatives have forced development towards a more integrated region with one regional identity. This has been complicated by border controls, redefining the national borders in an inconvenient way, especially for everyday transnational commuters. Through sem

"Ofta lägger man krut på helt fel saker" - En kvalitativ studie om socialsekreterares syn på barns delaktighet i socialtjänstens barnavårdsutredningar.

Children’s participation could seem to be an obvious ingredient in social services child protection investigations. Children’s rights to make their voice and opinion heard and to affect the decisions that involve them is stated in law, conventions and other regulations. Despite this, a lot of previous studies show that children’s rights often are forgotten or non-prioritized in social services. Th

Litteraturstudie över BDT-vattens miljö- och hälsopåverkan, lagstiftning och lämpliga lösningar för två utvalda koloniområden i Malmö

Hur ska vi ta hand om diskvattnet från kolonin? I Malmö finns en lång tradition av koloniträdgårdar som sträcker sig mer än 100 år tillbaka. Användningen av kolonierna har ändrat sig från att vara till för att odla grönskaer och för stadens arbetare att få möjlighet till återhämtning i lugn och hälsosam miljö, till att idag i stort sätt användas som fullt utrustade sommarstugor som familjen bor iPhosphorus and nitrogen causes eutrophication in the lakes and seas. One source for phosphorous and nitrogen is wastewater from households. To reduce the impact to the seas it is important to purify the wastewater sufficient.In my literature study I have investigated if the greywater (wastewater from bath/shower, dish och wash) has any environmental and health influence on the surroundings. I have

Automated 3D Bone Segmentation using Deep Learning in Scoliosis

Background: Scoliosis is a condition where a person's spine is curved and rotated in three dimensions. In severe cases, surgery is needed to straighten the spine. Before such complex procedures, meticulous planning is needed. By performing a CT-scan, images of the spine can be acquired. From these images, it is possible to segment the spine in three dimensions to facilitate the preparation. Ho

Winter is coming - Investigating urban design in a Winter city

All around the world is the form of the built environment playing a significant role in either enabling or inhibiting outdoor activities. When it comes to winter and Winter cities, it is a challenge how to enable and encourage outdoor activities and soft mobility as the harsh conditions often make it uncomfortable to spend longer periods of time outdoors. A major urban design challenge in Winter

BIM i Trafikverket - En kvalitativ undersökning av möjligheter och hinder för implementering

BIM, byggnadsinformationsmodellering, är ett arbetssätt som blir allt vanligare. Det innebär att olika objekt bygger upp en övergripande 3D-modell där man kan finna mängder av information om dessa objekt. Ett objekt kan vara allt ifrån en bropelare till en elstolpe. Syftet med denna rapport är att utifrån Trafikverkets roll som beställare undersöka vilka för- och nackdelar det skulle innebära med BIM, Building Information Modeling, is an increasingly common way of working. This means that different objects build up an overall 3D-model where you can find lots of information about these objects. An object can be anything from a bridge pillar to an electric pole. The purpose of this report is to, based on the Swedish Transport Administrations’ as a client, investigate the advantages and disad

A Child's Garden City: An Exploration of Child-Friendly Design in Today's Urban Spaces

Children do not have many spaces designed entirely for their needs in our world. This has inspired the concept of ‘A Child’s Garden City’. The idea includes research of how children can be included in design and the process of creating safer cities with their considerations in the center. This Master’s Thesis can inspire the relationship between growing natural vegetation, self-sustaining infrastr

Towards Establishment of an Ex Vivo Bladder Tumor Model using Precision Cut Tumor Slices (PCTS) for Evaluation of Existing and Novel Treatments

To continue the development of novel therapeutics to treat bladder cancer, a reliable model for preclinical testing of treatments and studying of the disease mechanism is essential. Ex vivo culturing of precision cut tumor slices (PCTS) provides a model that can retain the tumor architecture and its tumor microenvironment including the immune cell compartment, but data on PCTS based on bladder tum