Filetype
Patients with depression and suicidality suffer from low-grade neuroinflammation. Pro-inflammatory cytokines activate indoleamine 2,3-dioxygenase, an initial enzyme of the kynurenine pathway. This pathway produces neuroactive metabolites, including quinolinic- and kynurenic acid, binding to the glutamate N-methyl-d-aspartate-receptor, which is hypothesized to be part of the neural mechanisms under
Objective The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of SLE. Methods The classification criteria were derived from
The Minnesota Heart Health Program was a community trial of cardiovascular disease prevention methods that was conducted from 1980 to 1990 in three Upper Midwestern communities with three matched comparison communities. A 5- to 6-year intervention program used community-wide and individual health education in an attempt to decrease population risk. A major hypothesis was that the incidence of vali
Experience curves are used to analyse the prospects for diffusion and adoption of renewable energy technologies, with special emphasis on wind turbines and photovoltaic (PV) modules. The analysis shows that the possibility of cost reductions of renewable energy technologies is greater than for conventional energy technologies. However, large investments are necessary to make wind turbines and PV m
An approach to teaching calorimetry is offered through practical, versatile undergraduate experiments using an isothermal heat conduction calorimeter, which measures a variety of heat changes--enthalpies of phase changes, hydration, dissolution, adsorption and desorption, and reaction--as well as the metabolic rate of living organisms. Isothermal heat-conduction calorimetry is contrasted with adia
Agriculture in many African countries is characterised by large diversity in production and great variation in growing conditions, irrigation potential and access to markets. This variation has proved to be a difficult matter when adjusting national agricultural policies and development projects to local conditions. In the face of the recent trend of less support for agricultural extension servic
Popular Abstract in Swedish I rektorers uppdrag ingår ansvar för den pedagogiska verksamheten förändras och utvecklas. Den fråga som ställs i avhandlingen gäller om det finns en gemensam norm för hur rektorer tänker och handlar när det gäller den utvecklingsinriktade delen av ledaruppdraget. Om så är fallet hur ser den ut och kan den utvecklas? Bakgrund Stora förändringar på ett internationellt This thesis puts a focus on school leadership and school development. The local authorities took over responsibility for public education in 1991. At the same time, steerage by rules was abandoned in favour of steerage by goal-setting and result evaluation. The principal is an important link in this chain of steerage. The question posed by the thesis concerns whether there are common norms for th
Yeast-derived zymosan beads are among the classical agents used to induce sterile inflammatory responses in experimental animals and macrophage activation in cell culture. In macrophages the cytosolic phospholipase A2 becomes activated, leading to mobilization of arachidonate and the generation of prostaglandins and leukotrienes. Although zymosan can interact with several receptors it has not been
The laser-induced incandescence technique (LII) is a laser-based diagnostic technique for measurements of soot volume fraction and particle size. The technique relies on detection of incandescent light from soot particles heated to around 4000 K using nanosecond laser pulses. A theoretical model for LII has been implemented and improved in order to provide a tool for predicting the signal respons
Wastewater treatment plant operators encounter complex operational problems related to the activated sludge process and usually respond to these by applying their own intuition and by taking advantage of what they have learnt from past experiences of similar problems. However, previous process experiences are not easy to integrate in numerical control, and new tools must be developed to enable re-
Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non–insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximately 15–20% of families fitting MODY criteria do not have mutations in any of the known genes. These families provide a rich resource for the identificat
An analytical procedure based on microwave-assisted extraction (MAE) and standard addition was applied for the determination of banned azo dyes in bovine, sheep, and goat leather. Standard addition at four different concentration levels was performed using azo dyes, dissolved either in methanol or water. All dyes were determined indirectly by measuring their corresponding harmful aromatic amines,
Popular Abstract in Swedish Sedimentära bergarter såsom t.ex. sandstenar och lerskiffrar, bildas genom att lösa sediment (t.ex. sand och lera) ”bakas” hårda när de sjunker ned i jordskorpan. Anledningen till att många lagerföljder rör sig nedåt i jordskorpan beror till viss del på de ovanliggande sedimentens tyngd, men är i huvudsak ett resultat av de platt-tektoniska rörelser som hela tiden påverPost-depositional thermal conditions have been investigated throughout the Phanerozoic sedimentary succession in Skåne. Clay mineralogy and illite crystallinity have been the main tools for the Lower Palaeozoic strata. Within the Mesozoic sequence thermal influence was examined using RockEval pyrolysis and vitrinite reflectance analysis. Clay mineralogy of the Lower Palaeozoic shales and mudstone
Purpose: To compare the volume rendering technique (VRT) with maximum intensity projection (MIP) for aortic diameter measurements in MR angiography (MRA) data sets. Material and Methods: Existing contrast-enhanced 3-dimensional MRA and digital subtraction angiography (DSA) data sets from 20 patients were analyzed. In each MRA data set, two aortic diameters were measured using MIP and VRT. Agreemen
