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Negotiating Control : From Recognizing a Need to Making a Decision to Apply for a Housing Adaptation

A housing adaptation (HA) can enable independent living in one's own home, but deciding to change the home environment can be a thought-provoking matter. The aim of this study was to explore the applicant's perspective and decision-making process when applying for an HA grant. Seventeen persons were interviewed about their application for such a grant, and the data were analyzed using a constant c

Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2)

Structural technologies are an essential component in the design of precision therapeutics. Precision medicine entails the development of therapeutics directed toward a designated target protein, with the goal to deliver the right drug to the right patient at the right time. In the field of oncology, protein structural variants are often associated with oncogenic potential. In a previous proteogen

Blue straggler stars : Formation channels

I review formation channels for blue stragglers. I consider how they may be produced via collisions between two single main-sequence stars, or via collisions during encounters involving binary stars. Further, I discuss how blue stragglers may be produced via the evolution of isolated binaries. Observations of globular clusters suggest that both mechanisms are contributing.

Psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer : a population-based cohort study in Skåne, Sweden

BACKGROUND: An increasing number of women are evaluated for potential breast cancer and may experience mental distress during evaluation. We aim to assess the risks of psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer.METHODS: All women with a new diagnosis of unspecified lump in breast (N = 15,714), benign tumor or breast cancer in situ (N =

Cardiovascular Diseases And Psychiatric Disorders During The Diagnostic Workup Of Suspected Hematological Malignancy

Background: Little attention has been given to the risk of cardiovascular and psychiatric comorbidities during the clinical evaluation of a suspected hematological malignancy.Methods: Based on Skåne Healthcare Register, we performed a population-based cohort study of 1,527,449 individuals residing during 2005-2014 in Skåne, Sweden. We calculated the incidence rate ratios (IRRs) of cardiovascular d

Causes of Regional Change—Land Cover

Anthropogenic land-cover change (ALCC) is one of the few climate forcings for which the net direction of the climate response over the last two centuries is still not known. The uncertainty is due to the often counteracting temperature responses to the many biogeophysical effects and to the biogeochemical versus biogeophysical effects. Palaeoecological studies show that the major transformation of

Improving serious illness communication : a qualitative study of clinical culture

OBJECTIVE: Communication about patients' values, goals, and prognosis in serious illness (serious illness communication) is a cornerstone of person-centered care yet difficult to implement in practice. As part of Serious Illness Care Program implementation in five health systems, we studied the clinical culture-related factors that supported or impeded improvement in serious illness conversations.

Picosecond z-scan measurements of the two-photon absorption in beta-carotene solution over the 590-790 nm wavelength range

The two-photon absorption (TPA) properties of β-carotene (beta-carotene) in chloroform solution were investigated over the 590-790 nm wavelength range. The TPA was characterized using the open-aperture z-scan technique with picosecond pulses provided by a widely traveling-wave optical parametric amplifier (OPA) pumped with a Ti:sapphire laser amplifier. We found the 0.2-1 cm/GW values of two photo

Operationalizing the requirements selection process with study selection procedures from systematic literature reviews

Context: Software organizations working in a market-driven environment have to select requirements from a large pool to be prioritized and put into backlogs for the development organization. Objective: This paper proposes an approach based on study selection in systematic literature reviews and translates the concept to requirements engineering. The rational for doing so is that the selection proc

Health service utilisation associated with chronic breathlessness : Random population sample

Background Most health service utilisation studies are of people with specific diagnoses or demographic characteristics, and rarely of specific chronic symptoms. The aim of this study was to establish whether population-level health service utilisation increases in people with chronic breathlessness. Methods A cross-sectional analysis was carried out of the South Australian Health Omnibus Survey 2

The influence of “bad news” and “neutral/good news” on patients' perception of physician empathy during oncology consultations

ObjectivesBeing met with empathy increases information sharing, treatment coherence, and helps patients to recover faster. However, we do not know how the content of the conversation about disease progression, new treatments, or other issues concerning serious illness affects patients' perceptions of the physician's empathy, and thus, the quality of the conversation. This study aimed to test the h

Attitudes Toward Medical Assistance in Dying Among Swedish Palliative Care Professionals

Background: The debate over legalizing medical assistance in dying (assisted dying) is ongoing, also in Nordic countries such as Sweden where assisted dying is illegal. A 2020 survey by the Swedish Medical Association highlighted varied perspectives, with 41% of physicians supporting and 34% opposing legalization. Professionals in palliative care were more negative toward it. Objective: To ass

Should Benzodiazepines be Used for Reducing Dyspnea in Patients with Advanced Illnesses?

Dyspnea is a common and highly distressing symptom in patients with advanced illnesses. Many patients continue to experience chronic dyspnea despite optimal management of underlying disease(s) and various non-pharmacologic interventions, necessitating the consideration of pharmacologic therapies for palliation of dyspnea. One commonly asked question by clinicians is whether benzodiazepines have a

Compact Fluorosensor for Close-Range Remote-Sensing Characterization of Fruits

The ripeness of fruits is commonly assessed by the visual appearance, but this method is not very accurate and there can be a large variability. We have developed a hand-held sensor based on laser-induced fluorescence to provide more objective guidance. The instrument incorporates a 412 nm continuous wave semiconductor laser and a miniature spectrometer. It was used for monitoring of tropical frui

Uppsägning på grund av personliga skäl enligt lagen om anställningsskydd efter 2022 års ändringar

Lagen (1982:80) om anställningsskydd (LAS) genomgick år 2022 en reform som bland annat innebar en förändring av regleringen för uppsägning på grund av personliga skäl i 7 § LAS. Syftet var att öka förutsebarheten för både arbetsgivare och arbetstagare vid uppsägningar. Med hjälp av rättsdogmatisk metod syftar uppsatsen till att analysera och kartlägga reformen i förhållande till uppsägning på gruThe Employment Protection Act (LAS) underwent a reform in 2022 which, among other things, involved a change in the regulation regarding dismissals on personal grounds in Section 7. The purpose of the reform was to increase predictability for both employers and employees in cases of dismissals. Using a legal dogmatic method, the thesis aims to analyse and map the reform in relation to dismissal on

Engineering Design Integration & Non-Destructive Testing for the ESS accelerator

The ESS linac is under construction by the ESS partner institutes (socalled In-Kind Contributors - IKC) and will operate the most powerful proton beam ever for neutron spallation source. The linac delivers 5 MW via 2 GeV protons at a repetition rate of 14 Hz at the He-cooled solid tungsten target. The pulsed neutrons, result of the spallation, will reach the science instruments after having been m

Multi-beam ptychography with coded in-line Fresnel zone plates

X-ray ptychography is often implemented for nanoimaging at synchrotron radiation sources and extensions are being developed to make experiments faster. This work is on multi-beam ptychography with Fresnel zone plates that have a small lateral separation, enabling the imaging of an extended field of view without increasing exposure time. Sectional zone inversion is implemented for coding respective