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Association between obstructive sleep apnoea and cancer : a cross-sectional, population-based study of the DISCOVERY cohort

Objectives Nocturnal hypoxia in obstructive sleep apnoea (OSA) is a potential risk factor for cancer. We aimed to investigate the association between OSA measures and cancer prevalence in a large national patient cohort. Design Cross-sectional study. Settings 44 sleep centres in Sweden. Participants 62 811 patients from the Swedish registry for positive airway pressure (PAP) treatment in OSA, link

Breathlessness and exercise performance to predict mortality in long-term oxygen therapy - The population-based DISCOVERY study

BACKGROUND: Patients with chronic respiratory failure treated with long-term oxygen therapy (LTOT) often have severe breathlessness, impaired exercise performance, and high but variable mortality that is difficult to predict. We aimed to evaluate breathlessness and exercise performance upon starting LTOT as predictors of overall and short-term mortality.METHODS: This was a longitudinal, population

Impact of trigeminal nerve and/or olfactory nerve stimulation on activity of human brain regions involved in the perception of breathlessness

Breathlessness is a centrally processed symptom, as evidenced by activation of distinct brain regions such as the insular cortex and amygdala, during the anticipation and/or perception of breathlessness. Inhaled L-menthol or blowing cool air to the face/nose, both selective trigeminal nerve (TGN) stimulants, relieve breathlessness without concurrent improvements in physiological outcomes (e.g., br

Reference equations for breathlessness during incremental cycle exercise testing

Background Exertional breathlessness is commonly assessed using incremental exercise testing (IET), but reference equations for breathlessness responses are lacking. We aimed to develop reference equations for breathlessness intensity during IET. Methods A retrospective, consecutive cohort study of adults undergoing IET was carried out in Sweden. Exclusion criteria included cardiac or respiratory

Oral Methadone versus Morphine IR for Patients with Cervical Cancer and Neuropathic Pain : A Prospective Randomised Controlled Trial

Objectives: In India, cervical cancer is the most common cancer among women and makes up for up to 29% of all registered cancer in females. Cancer-related pain is one of the major distressing symptoms for all cancer patients. Pain is characterised as somatic or neuropathic, and the total pain experience is often mixed. Conventional opioids are the backbone of analgesic treatment but are most often

Materialising Modern Cemeteries : Archaeological narratives of Assistens cemetery, Copenhagen

This doctoral thesis examines the encounter between the dead and the living within 19th and 20th century landscape cemeteries. It shows how the relationship unfolds through the materiality and practices occurring within them.Landscape cemeteries were established from the late 18th century and with their garden-inspired design, location outside of the city and increasing secular administration were

Variable resolution images and their effects on eye-movements during free-viewing

Earlier studies have shown that while free-viewing images people tend to gaze at regions with a high local density of bottom up features such as contrast and edge density. In particular, this tendency seems to be more emphasized during the first few fixations after image onset. In this paper, we present a new method to investigate how gaze locations are chosen by introducing varying image resoluti

Hypertension, blood pressure, cognition and cerebral blood flow in the cohort of "Men born 1914"

Popular Abstract in Swedish Flertal studier talar för att såväl vaskulär demens som demens av Alzheimers typ är relaterade till blodtrycksnivå tidigare under livet. En studie har visat att redan blodtrycket vid 50- årsåldern är relaterat till kognitiva (intellektuella) funktioner vid 70-års ålder. En annan studie har visat att hypertoni i 70-årsåldern föregår utveckling av demens i ålder 80-85 år."Men born 1914" is a population based cohort study of the epidemiology of cardiovascular disease. Five hundred men, born 1914, were examined at the age of 68 and 185 of them were re-examined at 81 years of age. Examination included a medical and a psychological investigation, ultrasonographic measurement of carotid arteries, 24-hour ambulatory blood pressure monitoring, regional cerebral blood flo

Examples as Crucial Arguments on 'others'

In this article we take the classic meaning of exemplum as a point of departure to show how examples are marked and used in oral discourse on 'others'. The empirical material is a transcribed focus group interview with Swedish students talking about a trip to Warsaw. Examples may be marked in explicit ways but also in implicit ways. Some examples seem recognizable by their allusive nature, others

Species and gene divergence in Littorina snails detected by array comparative genomic hybridization

Background: Array comparative genomic hybridization (aCGH) is commonly used to screen different types of genetic variation in humans and model species. Here, we performed aCGH using an oligonucleotide gene-expression array for a non-model species, the intertidal snail Littorina saxatilis. First, we tested what types of genetic variation can be detected by this method using direct re-sequencing and

Från Jernverk till Hjärnverk : Ungdomstidens omvandling i Ronneby under tre generationer

Popular AbstractAvsikten med denna avhandling är att utveckla en teori om de försvårade villkor som män ur arbetarklassen och den lägre medelklassen upplevt i Ronneby sedan början av 1900-talet; om hur traditionen att snabbt komma ut i arbetslivet — som bland män i Ronneby i det närmaste har varit likvärdigt med att bli vuxen — ersatts av ett behov att senarelägga vuxenblivandet. Bakgrunden är attThe place is Ronneby, a smallish town in southern Sweden. My subjects are working class and lower middle class men in Ronneby, men who — since the beginning of the century — have encountered changing conditions for reaching adulthood. In this dissertation, I will analyse these changing and increasingly difficult conditions and try to explain how the tradition of starting to work early in life, and

Large Eddy Simulation of Turbulent Flows in Combustor Related Geometries

Numerical simulations using Large Eddy Simulation (LES) are applied to turbulent swirling flow fields. The swirling motion is often introduced into combustors to act as flame holders or enhance the mixing between species. Different turbulence models capture the swirling motion more or less accurately. LES is well suited for understanding details of swirling flows. It resolves all the large scales

Contrast-enhanced magnetic resonance angiography.

Contrast-enhanced magnetic resonance angiography (CE-MRA) is a diagnostic method for imaging of vascular structures based on nuclear magnetic resonance. Vascular enhancement is achieved by injection of a contrast medium (CM). Studies were performed using two different types of CM: conventional paramagnetic CM, and a new type of CM based on hyperpolarized (HP) nuclei. The effects of varying CM con

Fire, Poison, and Black Tears : Metaphors of Emotion in Rebétiko

Popular Abstract in Swedish Avhandlingen Fire, Poison, and Black Tears – Metaphors of Emotion in Rebétiko är som titeln anger en studie av metaforer för känslouttryck i rebétikomusikens texter. Den populärmusikaliska genren rebétiko är en utbredd musikstil i det moderna Grekland. Dess rötter kan spåras till det grekiska fastlandet, Mindre Asien, och de grekiska öarna, men den musikaliska formen haThis dissertation is a study of metaphors of emotion in rebétiko song texts. Rebétiko is a major popular-music style of modern Greece, consisting mostly of melancholic songs full of sorrow, disappointment, and misfortune, as well as passion and romance, but also of cheerful songs of revelry and a carefree attitude to life. Rebétiko as a music style developed in the Greek-speaking world and its dia

Diabetic Blood Glucose Control via Optimization over Insulin and Glucose Doses

The proposed algorithm aims at helping diabetic patients which use multi-dose injection (MDI) therapy to determine the dose and time of insulin and glucose intakes to stabilize their blood glucose (BG) concentration. The objective is to spend most of the time in normal BG range (70-180 mg/dl). The control was done by minimizing the risk of hypo- and hyperglycemia over the doses and times of insuli

Contact Allergy to Acrylates

Popular Abstract in Swedish Akrylatallergi Plastmaterial består av stora molekyler som kallas polymerer samt tillsatsämnen som tillsätts för att modifiera materialets egenskaper. Polymerer bildas när det sker en stegvis reaktion mellan monomerer så att större molekyler bildas. Allergiframkallande ämnen i plastsystem kan vara monomererna, härdarna, modifierarna eller andra tillsatsämnen. AkrylaterAcrylate contact allergy has been frequently reported since the 1970s, with hundreds of articles published in dermatology journals so far. The purpose of this thesis was to investigate the frequency of contact allergy to acrylates / methacrylates in patients with exposure to industrial, dental and nail uses of these substances. We also aimed to investigate the clinical and chemical aspects of pa

Nag Hammadi-sabbaten och den platslösa kategorin: Religiös förändring och självbildens transformation under senantiken

Many scholars and philosophers inspired by Antiquity, have commented upon a transformation of lived religion and a changing picture and technology of the Self during Late Antiquity. The Nag Hammadi Library contains a diverse body of thought and it is here argued that these texts are found in the epicentre of Late Antique conversion of religion and Self, containing important illustrations of new em